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Analgesic Rebound Headache

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Encyclopedia of Ophthalmology
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Synonyms

Analgesic rebound headache; Drug-induced headache; Medication misuse headache; Medication overuse headache; Rebound headache

Definition

Analgesic rebound headache may be caused by any medications used to treat headache including triptans, ergotamines, opioids, and other analgesics. Analgesic rebound headache typically results from the chronic overuse of analgesics for headache relief and is defined as a headache that has started or has worsened from the use of analgesic medications. This condition is primarily seen in individuals who have a chronic headache disorder, such as migraine, and take analgesics for pain relief more than two to three times per week for a period of more than 3 consecutive months. Analgesic rebound headache may even interfere with the proper treatment of an underlying chronic headache disorder.

Etiology

The exact mechanism for analgesic rebound headaches is not understood. There are a number of factors that may contribute, including sensitization to the...

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Further Reading

  • Diener HC, Limmroth V (2004) Medication-overuse headache: a worldwide problem. Lancet Neurol 3(8):475–483

    Article  PubMed  Google Scholar 

  • Gipponi S, Venturelli E, Rao R, Liberini P, Padovani A (2010) Hypertension is a factor associated with chronic daily headache. Neurol Sci 31(Suppl 1):S171–S173

    Article  PubMed  Google Scholar 

  • Nappi G, Perrotta A, Rossi P, Sandrini G (2008) Chronic daily headache. Expert Rev Neurother 8(3):361–384

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  • Rapoport AM (2006) Acute treatment of headache. J Headache Pain 7(5):355–359

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Andrew G. Lee .

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Lee, A.G., Khan, K., Almarzouqi, S.J., Morgan, M.L. (2015). Analgesic Rebound Headache. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_1156-1

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_1156-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-35951-4

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