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Measuring Mitochondrial Reactive Oxygen Species (ROS) Production

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Systems Biology of Free Radicals and Antioxidants

Abstract

We review the major classical approaches to measuring the rates of ROS emission in suspensions of isolated mitochondria and the most essential features of mitochondrial ROS metabolism. The purpose of this review is to assist in designing workable and scientifically sound assays of mitochondrial ROS generation and to help in understanding the accumulated experimental data on this subject.

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Authors and Affiliations

  1. Weill Medical College Cornell University, 585 E 68th street A501, New York, NY, 10021, USA

    Anatoly A. Starkov

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  1. Anatoly A. Starkov
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Correspondence to Anatoly A. Starkov .

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Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, University of British Colombia, Vancouver, British Columbia, Canada

    Ismail Laher

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Starkov, A.A. (2014). Measuring Mitochondrial Reactive Oxygen Species (ROS) Production. In: Laher, I. (eds) Systems Biology of Free Radicals and Antioxidants. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30018-9_8

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