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Age-Related Changes in Skin Mechanical Properties

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Textbook of Aging Skin

Abstract

Skin aging is accompanied by a variety of epidermal, dermal, and subcutaneous alterations including changes in pigmentation, volume, skin barrier function and mechanical properties. Although most of these signs of skin aging are somehow linked, the changes in mechanical properties are of special interest as they directly contribute to the development of wrinkles. While skin laxity is often seen first and most prominent at cheeks and neck, the loss of firmness is more general and becomes evident even in sun-protected areas. Although these signs of aging become visible lately, much later than wrinkles, the changes in skin elasticity begin early in life and progress continuously. To treat them most effectively, it is mandatory to understand the underlying dermal processes and how the skin mechanical properties change with aging. In addition, it is important to understand that skin ages differently in men and women due to the gender-related differences in the morphological distinction of dermal tissue. It is further of importance to understand the mechanical properties of the skin as a multiparametric function, influenced by a myriad of factors. It is inevitable to not only recognize all parameters as a whole but also to be able to relate to the measurement technique used to assess skin elasticity.

New data shows that the mechanical properties of the skin progressively decline with aging. This aging process affects the elastic ability of the skin to recover after stretching differently than the firmness of the skin. Furthermore, the mechanical properties not only vary significantly between the sexes, they also alter differently in men and women over lifetime. This knowledge can be helpful for a better understanding of the clinical genesis of facial wrinkles and age-related skin laxity as well as for the development and evaluation of effective treatment options for skin aging.

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References

  1. Tzaphlidou M. The role of collagen and elastin in aged skin: an image processing approach. Micron. 2004;35(3):173–7.

    Article  CAS  PubMed  Google Scholar 

  2. Callaghan TM, Wilhelm K-P. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: cellular and molecular perspectives of skin ageing. Int J Cosmet Sci. 2008;30(5):313–22.

    Article  CAS  PubMed  Google Scholar 

  3. Farage MA, Miller KW, Elsner P, Maibach HI. Intrinsic and extrinsic factors in skin ageing: a review. Int J Cosmet Sci. 2008;30(2):87–95.

    Article  CAS  PubMed  Google Scholar 

  4. Friedman O. Changes associated with the aging face. Facial Plast Surg Clin North Am. 2005;13(3):371–80.

    Article  PubMed  Google Scholar 

  5. Kligman AM, Zheng P, Lavker RM. The anatomy and pathogenesis of wrinkles. Br J Dermatol. 1985;113(1):37–42.

    Article  CAS  PubMed  Google Scholar 

  6. Luebberding S, Krueger N, Kerscher M. Life-time development of facial wrinkles of men and women: using three-dimensional fringe projection method and validated assessment scales. Dermatol Surg. 2014;40(1):22–32.

    Google Scholar 

  7. Akiba S, Shinkura R, Miyamoto K, Hillebrand G, Yamaguchi N, Ichihashi M. Influence of chronic UV exposure and lifestyle on facial skin photo-aging – results from a pilot study. J Epidemiol Jpn Epidemiol Assoc. 1999;9(6 Suppl):S136–42.

    Article  CAS  Google Scholar 

  8. Vitellaro-Zuccarello L, Cappelletti S, Dal Pozzo Rossi V, Sari-Gorla M. Stereological analysis of collagen and elastic fibers in the normal human dermis: variability with age, sex, and body region. Anat Rec. 1994;238(2):153–62.

    Article  CAS  PubMed  Google Scholar 

  9. Shuster S, Black MM, McVitie E. The influence of age and sex on skin thickness, skin collagen and density. Br J Dermatol. 1975;93(6):639–43.

    Article  CAS  PubMed  Google Scholar 

  10. Quaglino DJ, Bergamini G, Boraldi F, Pasquali Ronchetti I. Ultrastructural and morphometrical evaluations on normal human dermal connective tissue – the influence of age, sex and body region. Br J Dermatol. 1996;134(6):1013–22.

    Article  PubMed  Google Scholar 

  11. Rodrigues L. EEMCO guidance to the in vivo assessment of tensile functional properties of the skin. Skin Pharmacol Physiol. 2001;14(1):52–67.

    Article  CAS  Google Scholar 

  12. Wlaschek M, Tantcheva-Poór I, Naderi L, Ma W, Schneider LA, Razi-Wolf Z, et al. Solar UV irradiation and dermal photoaging. J Photochem Photobiol B. 2001;63(1–3):41–51.

    Article  CAS  PubMed  Google Scholar 

  13. Schneider LA, Wlaschek M, Scharffetter-Kochanek K. Skin aging. Clinical aspects and pathogenesis. J Dtsch Dermatol Ges. 2003;1(3):223–32; quiz 233–4.

    Article  PubMed  Google Scholar 

  14. Gniadecka M, Serup J. Suction chamber method for measuring skin mechanical properties: the Dermaflex®. In: Serup J, Jemec G, Grove G, editors. Non-invasive methods and skin. Boca Raton/New York/London: Taylor & Francis; 2006. p. 571–7.

    Chapter  Google Scholar 

  15. Oomens CW, van Campen DH, Grootenboer HJ. A mixture approach to the mechanics of skin. J Biomech. 1987;20(9):877–85.

    Article  CAS  PubMed  Google Scholar 

  16. Barel A. Suction chamber method for measurement of skin mechanics. The new digital version of the Cutometer. In: Serup J, Jemec GB, Grove GL, editors. Non-invasive methods and the skin. 2nd ed. Boca Raton/London/New York: Taylor & Francis; 2006. p. 583–91.

    Chapter  Google Scholar 

  17. Oxlund H. Changes in connective tissues during corticotrophin and corticosteroid treatment. Biomechanical and biochemical studies on muscle tendon, skin and aorta in experimental animals. Dan Med Bull. 1984;31(3):187–206.

    CAS  PubMed  Google Scholar 

  18. Oxlund H, Manschot J, Viidik A. The role of elastin in the mechanical properties of skin. J Biomech. 1988;21(3):213–8.

    Article  CAS  PubMed  Google Scholar 

  19. Vieira ACT, Vieira WT, Michalany N, Enokihara M, Freymüller E, Cestari SCP. Elastoderma of the neck in a teenage boy. J Am Acad Dermatol. 2005;53(2 Suppl 1):S147–9.

    Article  PubMed  Google Scholar 

  20. Kolácná L, Bakesová J, Varga F, Kostáková E, Plánka L, Necas A, et al. Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix. Physiol Res Acad Sci Bohemoslov. 2007;56 Suppl 1:S51–60.

    Google Scholar 

  21. Wan Abas WA, Barbenel JC. Uniaxial tension test of human skin in vivo. J Biomed Eng. 1982;4(1):65–71.

    Article  CAS  PubMed  Google Scholar 

  22. Agache P. Twistometry measurement of skin elasticity. In: Serup J, Jemec GBE, editors. Handbook of noninvasive methods and the skin. 1st ed. Boca Raton: CRC-Press; 1995. p. 319–28.

    Google Scholar 

  23. Hargens C. Ballistometry. In: Serup J, Jemec GBE, editors. Handbook of non-invasive methods and the skin. 1st ed. Boca Raton: Informa Healthcare; 1995. p. 359–66.

    Google Scholar 

  24. Agache P, Varchon D. Mechanical behaviour assessment. In: Agache P, Humbert P, editors. Measuring the skin: non-invasive investigations, physiology, normal constants. 1st ed. Berlin: Springer; 2004. p. 446–67.

    Chapter  Google Scholar 

  25. Cooper EP, Missel PJ, Hannon DP, Albright GB. Mechanical properties of dry, normal, and glycerol-treated skin as measured by the gas-bearing electrodynamometer. J Soc Cosmet Chem. 1985;36:335–48.

    Google Scholar 

  26. Bazin R, Fanchon C. Equivalence of face and volar forearm for the testing of moisturizing and firming effect of cosmetics in hydration and biomechanical studies. Int J Cosmet Sci. 2006;28(6):453–60.

    Article  CAS  PubMed  Google Scholar 

  27. Adhoute H, Berbis E, Privat Y. Ballistometric properties of aged skin. In: Leveque J-L, editor. Aging skin: properties and functional changes. Illustrated ed. Abingdon (UK): Informa Healthcare; 1993. p. 39–48.

    Google Scholar 

  28. Ahn S, Kim S, Lee H, Moon S, Chang I. Correlation between a Cutometer and quantitative evaluation using Moire topography in age-related skin elasticity. Skin Res Technol. 2007;13(3):280–4.

    Article  PubMed  Google Scholar 

  29. Cua AB, Wilhelm KP, Maibach HI. Elastic properties of human skin: relation to age, sex, and anatomical region. Arch Dermatol Res. 1990;282(5):283–8.

    Article  CAS  PubMed  Google Scholar 

  30. Ryu HS, Joo YH, Kim SO, Park KC, Youn SW. Influence of age and regional differences on skin elasticity as measured by the Cutometer. Skin Res Technol. 2008;14(3):354–8.

    Article  PubMed  Google Scholar 

  31. Grahame R. A method for measuring human skin elasticity in vivo with observations of the effects of age, sex and pregnancy. Clin Sci. 1970;39(2):223–9.

    Article  CAS  PubMed  Google Scholar 

  32. Choi JW, Kwon SH, Huh CH, Park KC, Youn SW. The influences of skin visco-elasticity, hydration level and aging on the formation of wrinkles: a comprehensive and objective approach. Skin Res Technol. 2013;19(1).

    Google Scholar 

  33. Mine S, Fortunel NO, Pageon H, Asselineau D. Aging alters functionally human dermal papillary fibroblasts but not reticular fibroblasts: a new view of skin morphogenesis and aging. PLoS One. 2008;3(12):e4066.

    Article  PubMed  PubMed Central  Google Scholar 

  34. O’goshi K-I. Suction chamber method for measurements of mechanics: the Cutometer. In: Serup J, Jemec G, Grove G, editors. Non-invasive methods and skin. Boca Raton/New York/London: Taylor & Francis; 2006. p. 579–82.

    Chapter  Google Scholar 

  35. Agache PG, Monneur C, Leveque JL, De Rigal J. Mechanical properties and Young’s modulus of human skin in vivo. Arch Dermatol Res. 1980;269(3):221–32.

    Article  CAS  PubMed  Google Scholar 

  36. Krueger N, Luebberding S, Oltmer M, Streker M, Kerscher M. Age-related changes in skin mechanical properties: a quantitative evaluation of 120 female subjects. Skin Res Technol. 2011;17(2):141–8.

    Article  PubMed  Google Scholar 

  37. Boyer G, Laquièze L, Le Bot A, Laquièze S, Zahouani H. Dynamic indentation on human skin in vivo: ageing effects. Skin Res Technol. 2009;15(1):55–67.

    Article  CAS  PubMed  Google Scholar 

  38. Luebberding S, Krueger N, Kerscher M. Mechanical properties of human skin in vivo: a comparative evaluation in 300 men and women. Skin Res Technol. 2014;20(2):127–35.

    Article  CAS  PubMed  Google Scholar 

  39. Braverman IM, Fonferko E. Studies in cutaneous aging: I. The elastic fiber network. J Invest Dermatol. 1982;78(5):434–43.

    Article  CAS  PubMed  Google Scholar 

  40. Frances C, Branchet MC, Boisnic S, Lesty CL, Robert L. Elastic fibers in normal human skin. Variations with age: a morphometric analysis. Arch Gerontol Geriatr. 1990;10(1):57–67.

    Article  CAS  PubMed  Google Scholar 

  41. Hillebrand GG, Liang Z, Yan X, Yoshii T. New wrinkles on wrinkling: an 8-year longitudinal study on the progression of expression lines into persistent wrinkles. Br J Dermatol. 2010;162(6):1233–41.

    Article  CAS  PubMed  Google Scholar 

  42. Phillips TJ, Symons J, Menon S. Does hormone therapy improve age-related skin changes in postmenopausal women? A randomized, double-blind, double-dummy, placebo-controlled multicenter study assessing the effects of norethindrone acetate and ethinyl estradiol in the improvement of mild to moderate age-related skin changes in postmenopausal women. J Am Acad Dermatol. 2008;59(3):397–404.e3.

    Article  PubMed  Google Scholar 

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Correspondence to Nils Krueger .

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Krueger, N., Luebberding, S. (2015). Age-Related Changes in Skin Mechanical Properties. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27814-3_116-1

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  • DOI: https://doi.org/10.1007/978-3-642-27814-3_116-1

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