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Acute Radiation Injuries

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Critical Care Toxicology

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Abstract

Acute exposure to ionizing radiation can cause acute injuries in a variety of settings or during a number of scenarios (Table 1). Because these incidents are infrequent, health-care providers may not be familiar with the evaluation and management of the resulting potentially life-threatening illnesses. This chapter will discuss the evaluation and management of acute radiation syndrome (ARS) and will include a concise discussion of internal contamination with radioactive materials and its clinical consequences.

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Author information

Authors and Affiliations

  1. Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA

    Ziad N. Kazzi

Authors
  1. Ziad N. Kazzi
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Corresponding author

Correspondence to Ziad N. Kazzi .

Editor information

Editors and Affiliations

  1. University of Colorado School of Medicine, Toxicology Associates, Denver, Colorado, USA

    Jeffrey Brent

  2. Office of New Drugs Drug Evaluation and Research, FDA, Silver Spring, Maryland, USA

    Keith Burkhart

  3. Clinical Toxicology, St Thomas' Hospital, London, United Kingdom

    Paul Dargan

  4. University of Colorado School of Medicine, Toxicology Associates, Denver, Colorado, USA

    Benjamin Hatten

  5. Med & Toxicological Intensive Care Unit, Lariboisière Hospital Paris-Diderot University, Paris, France

    Bruno Megarbane

  6. University of Colorado School of Medicine, Toxicology Associates, Denver, Colorado, USA

    Robert Palmer

Grading System for Levels of Evidence Supporting Recommendations in Critical Care Toxicology, 2nd Edition

Grading System for Levels of Evidence Supporting Recommendations in Critical Care Toxicology, 2nd Edition

  1. I

    Evidence obtained from at least one properly randomized controlled trial.

  2. II-1

    Evidence obtained from well-designed controlled trials without randomization.

  3. II-2

    Evidence obtained from well-designed cohort or case–control analytic studies, preferably from more than one center or research group.

  4. II-3

    Evidence obtained from multiple time series with or without the intervention. Dramatic results in uncontrolled experiments (such as the results of the introduction of penicillin treatment in the 1940s) could also be regarded as this type of evidence.

  5. III

    Opinions of respected authorities, based on clinical experience, descriptive studies, and case reports, or reports of expert committees.

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Kazzi, Z.N. (2016). Acute Radiation Injuries. In: Brent, J., Burkhart, K., Dargan, P., Hatten, B., Megarbane, B., Palmer, R. (eds) Critical Care Toxicology. Springer, Cham. https://doi.org/10.1007/978-3-319-20790-2_32-1

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  • DOI: https://doi.org/10.1007/978-3-319-20790-2_32-1

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  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-20790-2

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