Abstract
Endoscopic retrograde cholangiopancreatography (ERCP) is a complex and invasive procedure that is associated with adverse events including pancreatitis, bleeding, infection, perforation, cardiopulmonary complications, and rarely death. Technical success of this procedure relies on accessing the bile (and/or pancreatic) duct and being able to perform sphincterotomy safely. Standard cannulation methods are successful in the majority of cases; however, there are times when difficult biliary cannulation is encountered. In this setting advanced techniques for completion are required. Methods for biliary access include double guidewire technique, precut sphincterotomy, transpancreatic sphincterotomy, and others (endoscopic ultrasound or percutaneous transhepatic guided biliary drainage). In this chapter, we aim to review the standard and advanced techniques for biliary cannulation, predictors of difficult cannulation and methods for performing biliary sphincterotomy.
References
McCune WS et al (1968) Endoscopic cannulation of the ampulla of vater: a preliminary report. Ann Surg 167(5):752–756
Moffatt DC et al (2014) Trends in utilization of diagnostic and therapeutic ERCP and cholecystectomy over the past 25 years: a population-based study. Gastrointest Endosc 79(4):615–622
Adler DG et al (2005) ASGE guideline: the role of ERCP in diseases of the biliary tract and the pancreas. Gastrointest Endosc 62(1):1–8
Loperfido S et al (1998) Major early complications from diagnostic and therapeutic ERCP : a prospective multicenter study. Gastrointest Endosc 48(1):1–10
Freeman ML (2012) Complications of endoscopic retrograde cholangiopancreatography: avoidance and management. Gastrointest Endosc Clin N Am 22(3):567–586
Freeman ML et al (2001) Risk factors for post-ERCP pancreatitis: a prospective, multicenter study. Gastrointest Endosc 54(4):425–434
Williams EJ et al (2007) Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy 39(9):793–801
Freeman ML (2002) Adverse outcomes of ERCP. Gastrointest Endosc 56(6 Suppl):S273–S282
Testoni PA et al (2010) Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study. Am J Gastroenterol 105(8):1753–1761
Liao WC et al (2017) International consensus recommendations for difficult biliary access. Gastrointest Endosc 85(2):295–304
Halttunen J et al (2014) Difficult cannulation as defined by a prospective study of the Scandinavian Association for Digestive Endoscopy (SADE) in 907 ERCPs. Scand J Gastroenterol 49(6):752–758
Testoni PA et al (2016) Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline. Endoscopy 48(7):657–683
Ismail S et al (2019) Criteria for difficult biliary cannulation: start to count. Eur J Gastroenterol Hepatol 31(10):1200–1205
Jowell PS et al (1996) Quantitative assessment of procedural competence. A prospective study of training in endoscopic retrograde cholangiopancreatography. Ann Intern Med 125:983–989
Ekkelenkamp VE et al (2014) Competence development in ERCP: the learning curve of novice trainees. Endoscopy 46:969–955
Verma D et al (2007) Establishing a true assessment of endoscopic competence in ERCP during training and beyond: a single-operator learning curve for deep biliary cannulation in patients with native papillary anatomy. Gastrointest Endosc 65:394–400
Wani S et al (2016) Variation in learning curves and competence for ERCP among advanced endoscopy trainees by using cumulative sum analysis. Gastrointest Endosc 83(4):711–719.e11
Cortas GA et al (1999) Selective cannulation of the common bile duct: a prospective randomized trial comparing standard catheters with sphincterotomes. Gastrointest Endosc 50:775–779
Schwacha H et al (2000) A sphincterotome-based technique for selective transpapillary common bile duct cannulation. Gastrointest Endosc 52:387–391
Laasch HU et al (2003) Comparison of standard and steerable catheters for bile duct cannulation in ERCP. Endoscopy 35:669–674
Karamanolis G et al (2005) A prospective cross-over study using a sphincterotome and a guidewire to increase the success rate of common bile duct cannulation. World J Gastroenterol 11:1649–1652
Kitamura K et al (2015) 0.025-inch vs 0.035-inch guide wires for wire-guided cannulation during endoscopic retrograde cholangiopancreatography: a randomized study. World J Gastroenterol 21(30): 9182–9189188
Vihervaara H et al (2013) Angled- or straight-tipped hydrophilic guidewire in biliary cannulation: a prospective, randomized, controlled trial. Surg Endosc 27:1281–1286
TsuchiyaT et al (2015) J-Tip guidewire for selective biliary cannulation compared to conventional guidewires (the JANGLE study). Dig Dis Sci 60:2502–2508
Cheung J et al (2009) Guidewire versus conventional contrast cannulation of the common bile duct for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. Gastrointest Endosc 70:1211–1229
Tse F et al (2013) Guidewire-assisted cannulation for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. Endoscopy 45:605–618
Shao LM et al (2009) Can wire-guided cannulation reduce the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis? A meta-analysis of randomized controlled trials. J Gastroenterol Hepatol 24:1710–1715
Herreros de Tejada A et al (2009) Double-guidewire technique for difficult bile duct cannulation: a multicenter randomized, controlled trial. Gastrointest Endosc 70:700–709
Angsuwatcharakon P et al (2012) Success rate and cannulation time between precut sphincterotomy and double-guidewire technique in truly difficult biliary cannulation. J Gastroenterol Hepatol 27:356–3561
Coté GA et al (2012) Use of a pancreatic duct stent or guidewire facilitates bile duct access with low rates of precut sphincterotomy: a randomized clinical trial. Dig Dis Sci 57:3271–3278
Maeda S et al (2003) Prospective randomized pilot trial of selective biliary cannulation using pancreatic guide-wire placement. Endoscopy 35:721–724
Yoo YW et al (2013) Double guidewire technique vs transpancreatic precut sphincterotomy in difficult biliary cannulation. World J Gastroenterol 19:108–114
Ito K et al (2010) Can pancreatic duct stenting prevent postERCP pancreatitis in patients who undergo pancreatic duct guidewire placement for achieving selective biliary cannulation? A prospective randomized controlled trial. J Gastroenterol 45:1183–1191
Ito K et al (2014) Clinical usefulness of double-guidewire technique for difficult biliary cannulation in endoscopic retrograde cholangiopancreatography. Dig Endosc 26:442–449
Navaneethan U et al (2014) Early precut sphincterotomy and the risk of endoscopic retrograde cholangio-pancreatography related complications: an updated meta-analysis. World J Gastro-intest Endosc 6:200–208
Choudhary A et al (2014) Effect of precut sphincterotomy on post-endoscopic retrograde cholangio-pancreatography pancreatitis: a systematic review and meta-analysis. World J Gastroenterol 20:4093–4101
Mavrogiannis C et al (1999) Needle-knife fistulotomy versus needle-knife papillotomy for the treatment of common bile duct stones. Gastrointest Endosc 50:334–339
Katsinelos P et al (2012) Comparison of three types of precut technique to achieve common bile duct cannulation: a retrospective analysis of 274 cases. Dig Dis Sci 57:3286–3292
Zang J et al (2014) Guidewire-assisted transpancreatic sphincterotomy for difficult biliary cannulation: a prospective randomized con- trolled trial. Surg Laparosc Endosc Percutan Tech 24:429–433
Chun CG et al (2012) DGT vs. TPS in patients with initial PD cannulation by chance: prospective randomized multicenter study. Gastrointest Endosc 75:–AB141
Catalano MF et al (2004) Endoscopic transpancreatic papillary septotomy for inaccessible obstructed bile ducts: comparison with standard pre-cut papillotomy. Gastrointest Endosc 60:557–561
Kahaleh M et al (2004) Prospective evaluation of pancreatic sphincterotomy as a precut technique for biliary cannulation. Clin Gastroenterol Hepatol 2:971–977
Lee YJ et al (2015) Different strategies for transpancreatic septotomy and needle knife infundibulotomy due to the presence of unintended pancreatic cannulation in difficult biliary cannulation. Gut Liver 9:534–539
Halttunen J et al (2009) Pancreatic sphincterotomy versus needle knife precut in difficult biliary cannulation. Surg Endosc 23:745–749
Wang P et al (2010) Success and complication rates of two pre- cut techniques, transpancreatic sphincterotomy and needle-knife sphincterotomy for bile duct cannulation. J Gastrointest Surg 14:697–704
Kim J et al (2012) Results of repeat endoscopic retrograde cholangiopancreatography after initial biliary cannulation failure following needle-knife sphincterotomy. J Gastroenterol Hepatol 27:516–520
Burdick JS et al (2002) Intramural incision technique. Gastrointest Endosc 55:425–427
Misra SP, Dwivedi M (2008) Intramural incision technique: a useful and safe procedure for obtaining ductal access during ERCP. Gastrointest Endosc 67:629–633
Thomas R et al (2009) Biliary access in technically difficult biliary cannulation: the mucosal bridge technique. HPB (Oxford) 11:176–180
Geonke MK, Rai VK (2015) Burdick’s technique for biliary access revisited. Clin Endoscopy 48(1):20–23
Boix J et al (2006) Impact of periampullary duodenal diverticula at endoscopic retrograde cholangiopancreatography: a proposed classification of periampullary duodenal diverticula. Surg Laparosc Endosc Percutan Tech 16:208–211
Elmunzer BJ, Boetticher NC (2015) Reverse guidewire anchoring of the papilla for difficult cannulation due to a periampullary diverticulum. Gastrointest Endosc 82:957
Huang CH et al (2010) Endoscopic retrograde cholangiopancreatography (ERCP) for intradiverticular papilla: endoclip-assisted biliary cannulation. Endoscopy 42(Suppl 2):E223–E224
Fujita N et al (1998) ERCP for intradiverticular papilla: two-devices-in-one-channel method. Endoscopic retrograde Cholangiopancreatography. Gastrointest Endosc 48:517–520
Tóth E et al (1999) An alternative approach to the inaccessible intradiverticular papilla. Endoscopy 31:554–556
Myung DS et al (2014) Cap-assisted ERCP in patients with difficult cannulation due to periampullary diverticulum. Endoscopy 46:352–355
Külling D, Haskell E (2005) Double endoscope method to access intradiverticular papilla. Gastrointest Endosc 62:811–812
Leng J-J et al (2014) Percutaneous transhepatic and endoscopic biliary drainage for malignant biliary tract obstruction: a meta-analysis. World J Surgical Oncol 12:272
Kawai K et al (1974) Endoscopic sphincterotomy of the ampulla of Vater. Gastrointest Endosc 20(4):148–151
Classen M, Demling L (1974) Endoscopic sphincterotomy of the papilla of vater and extraction of stones from the choledochal duct (author's transl). Dtsch MedWochenschr 99(11):496–497. German
Raymondos K et al (2002) Evaluation of endoscopic retrograde cholangiopancreatography under conscious sedation and general anesthesia. Endoscopy 34(9):721–726. PubMed PMID: 12195330
Behrens A et al (2018) Acute sedation-associated complications in GI endoscopy (ProSed 2 study) results from the prospective multicentre electronic registry of sedation-associated complications. Gut 3. pii: gutjnl-2015-gutjn311037. https://doi.org/10.1136/gutjnl-2015-311037
Wang D et al (2013) The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis. PLoS One 8(1):e53311. https://doi.org/10.1371/journal.pone.0053311. Epub 2013 Jan 8. PubMed PMID: 23308191; PubMed Central PMCID: PMC3540096
Petersen BT et al (2007) Technology assessment committee. Endoscopy in patients with implanted electronic devices. Gastrointest Endosc 65(4):561–568. Review. PubMed PMID: 17383453
Veitch AM et al (2016) Endoscopy in patients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines. Endoscopy 48(4):c1. https://doi.org/10.1055/s-0042-122686
Verma D et al (2007) Pure versus mixed electrosurgical current for endoscopic biliary sphincterotomy: a meta-analysis of adverse outcomes. Gastrointest Endosc 66(2):283–290. Review
Ryozawa S et al (2018) Japan gastroenterological endoscopy society guidelines for endoscopic sphincterotomy. Dig Endosc 30(2):149–173. https://doi.org/10.1111/den.13001. Epub 2018 Jan 18
Mirjalili SA, Stringer MD (2011) The arterial supply of the major duodenal papilla and its relevance to endoscopic sphincterotomy. Endoscopy 43(4):307–311. https://doi.org/10.1055/s-0030-1256229. Epub 2011 Mar 31
Leung JW et al (1990) Precut (needle knife) papillotomy for impacted common bile duct stone at the ampulla. Am J Gastroenterol 85(8):991–993
Joo KR et al (2010) Case review of impacted bile duct stone at duodenal papilla: detection and endoscopic treatment. Yonsei Med J 51(4):534–539. https://doi.org/10.3349/ymj.2010.51.4.534
Park DH et al (2006) A novel method for estimating the safe margin and the adequate direction of endoscopic biliary sphincterotomy in choledocholithiasis with complications (with videos). Gastrointest Endosc 64(6):979–983
Siegel JH et al (1994) Stent-guided sphincterotomy. Gastrointest Endosc 40(5):567–572
Mavrogiannis C et al (2003) Safety of extension of a previous endoscopic sphincterotomy: a prospective study. Am J Gastroenterol 98(1):72–76
Ersoz G et al (2003) Biliary sphincterotomy plus dilation with a large balloon for bile duct stones that are difficult to extract. Gastrointest Endosc 57(2):156–159
Heo JH et al (2007) Endoscopic sphincterotomy plus large-balloon dilation versus endoscopic sphincterotomy for removal of bile-duct stones. Gastrointest Endosc 66(4):720–726. quiz 768, 771
Liao WC et al (2012) Balloon dilation with adequate duration is safer than sphincterotomy for extracting bile duct stones: a systematic review and meta-analyses. Clin Gastroenterol Hepatol 10(10):1101–1109. https://doi.org/10.1016/j.cgh.2012.05.017. Epub 2012 May 27
Zhao HC et al (2013) Meta-analysis comparison of endoscopic papillary balloon dilatation and endoscopic sphincteropapillotomy. World J Gastroenterol 28(19):24.):3883-91. https://doi.org/10.3748/wjg.v19.i24.3883.
Cochrane J, Schlepp G (2016) Comparing endoscopic intervention against fully covered self-expanding metal stent placement for post-endoscopic sphincterotomy bleed (CEASE study). Endosc Int Open 4(12):E1261–E1264. Epub 2016 Nov 24
Canard JM, Lennon AM, Letard J et al. (2011) Endoscopic retrograde cholangiopancreatography. In: Canard JM (ed) Gastrointestinal Endoscopy in Practice. Churchill Livingstone, London, p370-465
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this entry
Cite this entry
Williams, E.J., Krishnan, B., Lau, S.Y. (2021). Difficult Biliary Cannulation and Sphincterotomy: What to Do. In: Testoni, P.A., Inoue, H., Wallace, M.B. (eds) Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-29964-4_65-2
Download citation
DOI: https://doi.org/10.1007/978-3-030-29964-4_65-2
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-29964-4
Online ISBN: 978-3-030-29964-4
eBook Packages: Springer Reference MedicineReference Module Medicine
Publish with us
Chapter history
-
Latest
Difficult Biliary Cannulation and Sphincterotomy: What to Do- Published:
- 10 August 2021
DOI: https://doi.org/10.1007/978-3-030-29964-4_65-2
-
Original
Difficult Biliary Cannulation and Sphinterotomy: What to Do- Published:
- 09 June 2021
DOI: https://doi.org/10.1007/978-3-030-29964-4_65-1