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Parkinson’s Disease and Deep Brain Stimulation

Encyclopedia of Computational Neuroscience

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Synonyms

Chronic electrical stimulation; Deep brain stimulation; High-frequency stimulation; Idiopathic Parkinson’s disease; Neuromodulation; Paralysis agitans; Shaking palsy

Definitions

Chronic electrical stimulation also called deep brain stimulation (DBS) of specific nuclei in the basal ganglia is currently used to treat patients with movement disorders related to Parkinson’s disease (PD). This entry reviews the clinical uses of, and mechanisms of, DBS to treat symptoms developed by patients with PD. The hope is that computational studies will lead to the development of better stimulation protocols which have better efficacy and involve DBS closed-loop stimulators with prolonged battery life.

Parkinson’s Disease

Parkinson’s disease (PD), the second most common neurodegenerative disease of the central nervous system after Alzheimer’s disease, affects more than six million people in the world and 1.2 million in Europe. This represents about 1 % of the global population over 50 years...

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Authors and Affiliations

  1. Institut Polytechnique de Bordeaux, 1 avenue du Dr Albert Schweitzer, 33402, Talence, France

    Anne Beuter Ph.D.

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  1. Anne Beuter Ph.D.
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Correspondence to Anne Beuter Ph.D. .

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Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Beuter, A. (2013). Parkinson’s Disease and Deep Brain Stimulation. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_510-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_510-1

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  • Online ISBN: 978-1-4614-7320-6

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Chapter history

  1. Latest

    Parkinson’s Disease: Deep Brain Stimulation
    Published:
    06 July 2018

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_510-3

  2. Parkinson’s Disease: Deep Brain Stimulation
    Published:
    08 May 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_510-2

  3. Original

    Parkinson’s Disease and Deep Brain Stimulation
    Published:
    08 February 2014

    DOI: https://doi.org/10.1007/978-1-4614-7320-6_510-1

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