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Calcium Regulation by EF-hand Protein in the Brain

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Handbook of Neurochemistry and Molecular Neurobiology

Abstract

The EF-hand containing calcium-binding proteins (CaBP) form a large family of proteins that is continuously growing, adding more complexity to calcium-dependent cellular processes. In this review, we give an overview of the different classes of EF-hand containing CaBP that play important roles in the CNS. We have indicated the cellular function, when known, of each protein, as well as its main target proteins in relation to the function.

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Abbreviations

CaM:

Calmodulin

DAPK:

death-associated protein kinase

GCAP:

Guanylate Cyclase-Activating Protein

KChIPs:

potassium channel interacting proteins

NCS:

neuronal calcium sensors

VILIP:

Visinin-like Protein

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Acknowledgments

This work was supported in part by NCCR on Neural Plasticity and Repair and the Transregio Sonderforschungsbereich TR SFB 11 Konstanz/Zürich.

Authors
  1. E. Leclerc
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  2. E. Sturchler
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  3. C. W. Heizmann
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Editors and Affiliations

  1. Center for Neurochemistry, Nathan S. Kline Institute for Psychiatric Research, 10962, 140 Old Orangeburg Road, Orangeburg, New York, USA

    Abel Lajtha (Director) (Director)

  2. Group Director of Neuro-Developmental Disorder Research Group, RIKEN Brain Science Institute, 351-0198, 2-1 Hirosawa Wako-shi, Saitama, Japan

    Katsuhiko Mikoshiba

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Leclerc, E., Sturchler, E., Heizmann, C.W. (2009). Calcium Regulation by EF-hand Protein in the Brain. In: Lajtha, A., Mikoshiba, K. (eds) Handbook of Neurochemistry and Molecular Neurobiology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-30370-3_27

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