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Alkaliphilic Prokaryotes

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The Prokaryotes

1 Introduction and Definitions

Alkaliphilic prokaryotes offer a wealth of opportunities for the isolation of natural products that can be advantageously applied to diverse industrial processes (Horikoshi and Akiba, 1982; Horikoshi, 1991; Horikoshi, 1996). Alkaliphiles also offer a wealth of opportunities to understand the mechanisms by which organisms thrive at pH 10–11.5, often present with other environmental challenges, such as high salt and high temperature (Krulwich, 1995; Krulwich et al., 1998). The diversity of alkaliphiles, which occur among aerobic and anaerobic archaea and prokaryotes as well as eukaryotic fungi (Grant et al., 1990; Jones et al., 1994; Horikoshi, 1991), likely broadens their industrial application. All alkaliphiles confront protein structure and function problems that involve catalysis at the external pH and regulation of cytoplasmic pH. However, among different alkaliphile groups, such as anaerobes, aerobes, ammonium-requiring sulfate-reducing thermophiles,...

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Krulwich, T.A. (2006). Alkaliphilic Prokaryotes. In: Dworkin, M., Falkow, S., Rosenberg, E., Schleifer, KH., Stackebrandt, E. (eds) The Prokaryotes. Springer, New York, NY. https://doi.org/10.1007/0-387-30742-7_10

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