Structure-based design, synthesis, and anticonvulsant activity of isatin-1-N-phenylacetamide derivatives Chao XieLi-Ming TangSi-Hong Wang Original Research 10 October 2013 Pages: 2161 - 2168
Design, synthesis, and evaluation of novel 1-methyl-3-substituted quinazoline-2,4-dione derivatives as antimicrobial agents Qing-Gang JiDan YangLv-Jiang Yuan Original Research 10 October 2013 Pages: 2169 - 2177
Design, synthesis and biological evaluation of 4-(1-(4(sulphanilamide)phenyl)-3-(methyl)-1H-pyrazol-5-yl)dine urea and N-acyl derivatives as a soluble epoxide hydrolase inhibitors Vijaykumar D. NimbarteHadianawala MurtuzaKrishnam Raju Atcha Original Research 10 October 2013 Pages: 2178 - 2197
Molecular docking- and genetic algorithm-based approaches to produce robust 3D-QSAR models Reaz UddinMaria SaeedZaheer Ul-Haq Original Research 13 October 2013 Pages: 2198 - 2206
Synthesis, characterization antibacterial and antifungal activity of some transition metal complexes Wajid RehmanZonera HassanMuhammad Waseem Original Research 13 October 2013 Pages: 2207 - 2211
Synthesis of halogenated derivatives of thymol and their antimicrobial activities Ranjeet KaurMahendra P. DarokarAteeque Ahmad Original Research 15 October 2013 Pages: 2212 - 2217
Discovery of new antitubercular agents by combining pyrazoline and benzoxazole pharmacophores: design, synthesis and insights into the binding interactions Dharmarajsinh N. RanaMahesh T. ChhabriaPathik S. Brahmkshatriya Original Research 15 October 2013 Pages: 2218 - 2228
3D QSAR and docking studies of a series of histone deacetylase inhibitors Xiaoguang LiYingjie ZhangWenfang Xu Original Research 15 October 2013 Pages: 2229 - 2241
Phosphorylated ganciclovir derivatives: design, synthesis and in vitro and in vivo immunomodulatory activity Kuruva Chandra SekharDevineni Subba RaoChamarthi Naga Raju Original Research 15 October 2013 Pages: 2242 - 2251
Molecular docking and 3D-QSAR studies on the MAPKAP-K2 inhibitors Eslam PourbasheerRoya BazlMassoud Amanlou Original Research 15 October 2013 Pages: 2252 - 2263
QSAR study of Nav1.7 antagonists by multiple linear regression method based on genetic algorithm (GA–MLR) Eslam PourbasheerReza AalizadehConstantinos Methenitis Original Research 15 October 2013 Pages: 2264 - 2276
Cytotoxicity and DNA-binding property of water-soluble naphthalene diimide derivatives bearing 2-oligoethoxy ethanamine side chain end-labeled with tertiary amino groups Haiying WeiMengjiao LvHua Chen Original Research 15 October 2013 Pages: 2277 - 2286
Discovery of new lead pyrimidines derivatives as potential cannabinoid CB1 receptor antagonistic through molecular modeling and pharmacophore approach Mukesh C. Sharma Original Research 16 October 2013 Pages: 2287 - 2311
Identification of irreversible protein splicing inhibitors as potential anti-TB drugs: insight from hybrid non-covalent/covalent docking virtual screening and molecular dynamics simulations Lauren BlakeMahmoud E. S. Soliman Original Research 16 October 2013 Pages: 2312 - 2323
Thrombin inhibitory activity of some polyphenolic compounds M. BijakR. ZiewieckiP. Nowak Original Research Open access 16 October 2013 Pages: 2324 - 2337
Synthesis and biological evaluation of novel quinazoline derivatives obtained by Suzuki C–C coupling Amit B. PatelKishor H. ChikhaliaPremlata Kumari Original Research 16 October 2013 Pages: 2338 - 2346
Synthesis of water soluble copper(II) complexes: crystal structures, DNA binding, oxidative DNA cleavage, and in vitro anticancer studies Tan Yi HanTeoh Siang GuanA. M. S. Abdul Majid Original Research 17 October 2013 Pages: 2347 - 2359
Optimization of enzyme-based ultrasonic/microwave-assisted extraction and evaluation of antioxidant activity of orcinol glucoside from the rhizomes of Curculigo orchioides Gaertn. Xin LiuYan HuDongfeng Wei Original Research 17 October 2013 Pages: 2360 - 2367
Synthesis of new indazole derivatives as potential antioxidant agents Majal SapnakumariBadiadka NarayanaLeelavathi Narayana Madhu Original Research 17 October 2013 Pages: 2368 - 2376
A comparative study of antimicrobial properties of cyclo(l-Pro- l-Asp) with its 2-ketopiperazine analog Chandrasekhar ChallaNishanth KumarRavi S. Lankalapalli Original Research 17 October 2013 Pages: 2377 - 2385
Withanolides isolated from Withania somnifera with α-glucosidase inhibition Murad Ali KhanHaroon KhanTahir Ali Original Research 17 October 2013 Pages: 2386 - 2390
Structural and energetic insights into the selective interactions of monoacylglycerol lipase with its natural substrate and small-molecule inhibitors Huayou ChenTengyun SunZhong Ni Original Research 18 October 2013 Pages: 2391 - 2404
Reversible redox system-based drug design, synthesis, and evaluation for targeting nitrogen mustard across brain Rajesh K. SinghSahil KumarT. R. Bhardwaj Original Research 18 October 2013 Pages: 2405 - 2416
An efficient synthesis, characterization, and antimicrobial screening of tetrahydropyrimidine derivatives Dinesh R. GodhaniPurvesh B. DobariyaJignasu P. Mehta Original Research 20 October 2013 Pages: 2417 - 2425
Synthesis and anticancer activity evaluation of new 1,2,3-triazole-4-carboxamide derivatives Nazariy PokhodyloOlga ShyykaVasyl Matiychuk Original Research 20 October 2013 Pages: 2426 - 2438
Synergistic effects of berberines with antibiotics on clinical multi-drug resistant isolates of methicillin-resistant Staphylococcus aureus (MRSA) Guo-Ying ZuoYang LiJun Han Original Research 20 October 2013 Pages: 2439 - 2444
Virtual screening based on pharmacophoric features of known calpain inhibitors to identify potent inhibitors of calpain Arumugam Ramachandran MuralidharanChandrabose SelvarajPhilip A. Thomas Original Research 22 October 2013 Pages: 2445 - 2455
Molecular modeling studies of JNK3 inhibitors using QSAR and docking Xiang-Xiang WuDa-Shun DaiChun-Lei Zhao Original Research 23 October 2013 Pages: 2456 - 2475
Spectroscopic, antiproliferative and antiradical properties of Cu(II), Ni(II), and Zn(II) complexes with amino acid based Schiff bases Zuhal Karagoz GencSibel SelcukMustafa Karatepe Original Research 23 October 2013 Pages: 2476 - 2485
Comparative QSAR and pharmacophore analysis for a series of 2,4-dihydro-3H-1,2,4-triazol-3-ones derivatives as angiotensin II AT1 receptor antagonists Mukesh C. SharmaSmita SharmaKamlendra Singh Bhadoriya Original Research 23 October 2013 Pages: 2486 - 2502
Microwave-assisted synthesis and anticonvulsant activity of 5,6-bisaryl-1,2,4-triazine-3-thiol derivatives Hamid IrannejadNima NaderiSakineh Dadashpour Original Research 23 October 2013 Pages: 2503 - 2514
Pharmacological evaluation of some novel synthesized compounds derived from spiro(cyclohexane-1,2′-thiazolidines) Eman M. FlefelHayam H. SayedFarouk M. E. Abdel-Megeid Original Research 24 October 2013 Pages: 2515 - 2527
In silico identification of the active conformation of open-chain enaminones with anticonvulsant activity Juan C. Garro MartinezEsteban G. Vega-HissiMario R. Estrada Original Research 26 October 2013 Pages: 2528 - 2535
Synthesis, characterization, and anti-rheumatic potential of phthalazine-1,4-dione and its Cu(II) and Zn(II) complexes Yousery E. SherifNasser M. Hosny Original Research 26 October 2013 Pages: 2536 - 2542
Optimization of phage heptapeptide library-screening process for developing inhibitors of the isocitrate lyase homologue from Mycobacterium tuberculosis Xintao LiuYang ZangYuhe Yin Original Research 26 October 2013 Pages: 2543 - 2553
Descriptors requirement for QSAR analysis of pyrazolo-triazolo-pyrimidine derivative as human A3 receptor antagonists: design of novel furan derivatives and validation by docking Laxman M. PrajapatiJimish R. PatelVijay K. Parmar Original Research 26 October 2013 Pages: 2554 - 2563
Design, synthesis, and evaluation of 4-(substituted)phenyl-2-thioxo-3,4-dihydro-1H-chromino[4,3-d]pyrimidin-5-one and 4-(substituted)phenyl-3,4-dihydro-1H-chromino[4,3-d]pyrimidine-2,5-dione analogs as antitubercular agents Premlata K. AmbreRaghuvir R. S. PissurlenkarEvans C. Coutinho Original Research 26 October 2013 Pages: 2564 - 2575
3D-QSAR and docking studies of piperidine carboxamide derivatives as ALK inhibitors Peng WangJin CaiMin Ji Original Research 26 October 2013 Pages: 2576 - 2583
Synthesis and antitumor properties of novel curcumin analogs Hui LuoShengjie YangHongmei Xiang Original Research 26 October 2013 Pages: 2584 - 2595
Novel metal complexes, their spectrophotometric and QSAR studies Güzin AslanZülbiye Onal Original Research 27 October 2013 Pages: 2596 - 2607
DABCO-promoted one-pot synthesis of heteroaryl-substituted benzenes and their biological evaluation G. Neelaiah BabuHaile Micheal AyalewShubha Jain Original Research 27 October 2013 Pages: 2608 - 2614
New synthetic approach to coumarino[4,3-b]pyridine systems and potential cytotoxic evaluation Wafaa S. HamamaMona E. IbrahimHanafi H. Zoorob Original Research 27 October 2013 Pages: 2615 - 2621
Analysis of surface area features of structurally diverse molecules for Bcr/Abl kinase inhibitory activity and antiproliferative activity N. S. Hari Narayana MoorthyC. KarthikeyanP. Trivedi Original Research 27 October 2013 Pages: 2622 - 2632
Synthesis, characterization, and antimicrobial evaluation of novel trichalcones containing core s-triazine moiety Firdous G. KhanManjusha V. YadavAshok D. Sagar Original Research 29 October 2013 Pages: 2633 - 2638
QSAR study of active human glucagon receptor antagonists by SW-MLR and SW-SVM methods Javad ShadmaneshAiyoub Parchehbaf JadidMahdi Shahmohammadi Aghbolagh Original Research 29 October 2013 Pages: 2639 - 2650
A new pipeline to discover antimycotics by inhibiting ergosterol and riboflavin synthesis: the inspirations of Siddha medicine G. PrasannaA. UjwalN. T. Saraswathi Original Research 30 October 2013 Pages: 2651 - 2658
Synthesis, characterization, DNA interaction, and antitumor activities of mixed-ligand metal complexes of kaempferol and 1,10-phenanthroline/2,2′-bipyridine Qin WangMin HuangXin-Bin Yang Original Research 30 October 2013 Pages: 2659 - 2666
Synthesis of novel bioactive pyrazolothiazoles S. YuvarajMonica MendonManju Girish Original Research 31 October 2013 Pages: 2667 - 2675
Synthesis, characterization, and computational studies on phthalic anhydride-based benzylidene-hydrazide derivatives as novel, potential anti-inflammatory agents Anu KajalSuman BalaVipin Saini Original Research 31 October 2013 Pages: 2676 - 2689
Design, synthesis, and PASS-assisted evaluation of novel 2-substituted benzimidazole derivatives as potent anthelmintics Kamalpriya GargYogita BansalR. K. Goel Original Research 31 October 2013 Pages: 2690 - 2697
