Volume 20, Issue 9 | Medicinal Chemistry Research

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Volume 20, Issue 9

December 2011

Special Issue: Current Trends In Drug Discovery Research; 17th-21st February, 2010 at Lucknow, India

Issue Editor:

Anil Kumar Saxena

44 articles in this issue

Current trends in drug discovery research “CTDDR-2010”
Anil K. Saxena
Guest Editorial - CTDDR-2010 03 December 2010 Pages: 1421 - 1421
3D-pharmacophore model based virtual screening to identify dual-binding site and selective acetylcholinesterase inhibitors
Shikhar Gupta
C. Gopi Mohan
Original Research 30 May 2010 Pages: 1422 - 1430
Antihyperglycemic, α-glucosidase inhibitory and DPPH free radical scavenging activity of 5-bromosalicylaldehyde and schiff bases
Sristicheta Misra
Krishna Bihari Pandeya
Kuncha Madhusudana
Original Research 10 June 2010 Pages: 1431 - 1437
Zn(Proline)₂-catalyzed Knoevenagel condensation under solvent-free/aqueous conditions and biological evaluation of products
Zeba N. Siddiqui
T. N. Mohammed Musthafa
Farheen Farooq
Original Research 17 June 2010 Pages: 1438 - 1444
Drug discovery against H1N1 virus (influenza A virus) via computational virtual screening approach
Ashwani Sharma
Ashish V. Tendulkar
Pramod P. Wangikar
Original Research 15 June 2010 Pages: 1445 - 1449
Identification of important structural features of thiazolo[4,5-d]pyrimidines required for potent antifungal activity
Mahesh Chhabria
Ishwarsinh Rathod
Paulomi Patel
Original Research 27 June 2010 Pages: 1450 - 1454
3D-QSAR CoMFA and CoMSIA studies on a set of diverse α_1a-adrenergic receptor antagonists
Amit K. Gupta
Anil K. Saxena
Original Research 13 July 2010 Pages: 1455 - 1464
Synthesis of analogues of antihyperglycemic lead karanjin
Akanksha
Prem P. Yadav
Rakesh Maurya
Original Research 18 July 2010 Pages: 1465 - 1472
Microwave-assisted solvent-free synthesis of biologically active novel heterocycles from 3-formylchromones
T. N. Mohammed Musthafa
Zeba N. Siddiqui
Iqbal Ahmad
Original Research 20 July 2010 Pages: 1473 - 1481
Novel GABA-AT inhibitors: QSAR and docking based virtual screening of phenyl substituted β-phenyl ethylidene hydrazine analogues
S. K. Bansal
B. N. Sinha
A. J. Olson
Original Research 25 July 2010 Pages: 1482 - 1489
Synthesis characterization and biological evaluation of some alkoxyphthalimide derivatives of 3-(4-substituted phenyl)-6,6-diphenyl-3,3a-dihydro-2H-imidazo[2,1-b]pyrazolo[3,4-d][1,3]thiazol-7(6H)-one
Raja Ram Dangi
Nasir Hussain
Ganpat Lal Talesara
Original Research 31 July 2010 Pages: 1490 - 1498
Nicotinic acid hydrazones: a novel anticonvulsant pharmacophore
Reema Sinha
U. V. Singh Sara
Jainendra Jain
Original Research 03 August 2010 Pages: 1499 - 1504
Major alkaloidal constituent from Impatiens niamniamensis seeds as antihyperglycemic agent
Kailash Chand
Akanksha
Rakesh Maurya
Original Research 05 August 2010 Pages: 1505 - 1508
PASS-assisted exploration of new therapeutic potential of natural products
Rajesh Kumar Goel
Damanpreet Singh
Vladimir Poroikov
Original Research 06 August 2010 Pages: 1509 - 1514
Search of antimycobacterial activities in hybrid molecules with benzopyran skeleton
Rama P. Tripathi
Surendra Singh Bisht
Vinita Chaturvedi
Original Research 06 August 2010 Pages: 1515 - 1522
Synthesis and in vitro and in vivo antimalarial activity of novel 4-anilinoquinoline Mannich base derivatives
Bhupendra Singh
Dipak Chetia
Anil Prakash
Original Research 11 August 2010 Pages: 1523 - 1529
QSAR modeling of the inhibition of reverse transcriptase enzyme with benzimidazolone analogs
Surendra Kumar
Vineet Singh
Meena Tiwari
Original Research 19 August 2010 Pages: 1530 - 1541
Stability of Murraya koenigii miraculin-like protein in different physicochemical conditions
Girijesh K. Patel
Chandan Shee
Ashwani K. Sharma
Original Research 21 August 2010 Pages: 1542 - 1549
Quantitative structure activity relationship (QSAR) studies of a series of 2,5-disubstituted-1,3,4-oxadiazole derivatives as biologically potential compounds
Tanushree Pal
Rakesh R. Somani
Umesh V. Bhanushali
Original Research 29 August 2010 Pages: 1550 - 1555
Part of 1 collection:

Anti-HIV activity
Modeling of novel HIV-1 protease inhibitors incorporating N-Aryl-oxazolidinone-5-carboxamides as P2 ligands using quantum chemical and topological finger print descriptors
Shalini Singh
Sarika Singh
Poonam Shukla
Original Research 06 September 2010 Pages: 1556 - 1565
LC–MS/MS method for simultaneous analysis of cladrin and equol in rat plasma and its application in pharmacokinetics study of cladrin
Lakshmi Manickavasagam
Sonal Gupta
Girish Kumar Jain
Original Research 07 September 2010 Pages: 1566 - 1572
QSAR study of a series of acyl coenzyme A (CoA): cholesterol acyltransferase inhibitors using genetic function approximation
Mahesh T. Chhabria
Bhushan M. Mahajan
Pathik S. Brahmkshatriya
Original Research 10 September 2010 Pages: 1573 - 1580
Bioanalytical method development and validation for simultaneous estimation of (R)- and (S)-isomers of S002-333: a potent novel anti-thrombotic agent using LC–MS/MS
R. S. Bhatta
Y. S. Chhonker
G. K. Jain
Original Research 17 September 2010 Pages: 1581 - 1588
Antidyslipidemic and antioxidant activity of Pinus roxburghii needles
Anju Puri
Anuj K. Srivastava
V. Lakshmi
Original Research 18 September 2010 Pages: 1589 - 1593
Antifilarial efficacy of Hibiscus sabdariffa on lymphatic filarial parasite Brugia malayi
K. Saxena
V. Dube
P. K. Murthy
Original Research 19 September 2010 Pages: 1594 - 1602
Synthesis and antibacterial evaluation of series of novel tri-substituted-s-triazine derivatives
Udaya Pratap Singh
Ramendra Kumar Singh
Prashant Gahtori
Original Research 29 September 2010 Pages: 1603 - 1610
Studies on toxicity of antitubercular drugs namely isoniazid, rifampicin, and pyrazinamide in an in vitro model of HepG2 cell line
Meenakshi Singh
Preetha Sasi
Pramod P. Wangikar
Original Research 15 August 2010 Pages: 1611 - 1615
3D QSAR kNN-MFA studies on thiouracil derivatives as hepatitis C virus inhibitors
Vaishali M. Patil
S. P. Gupta
Neeraj Masand
Original Research 06 October 2010 Pages: 1616 - 1621
Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats
G. Bhatia
A. K. Khanna
V. Lakshmi
Original Research 06 October 2010 Pages: 1622 - 1626
Intravenous pharmacokinetics and oral bioavailability of biochanin A in female rats
Sheelendra Pratap Singh
Wahajuddin
Girish Kumar Jain
Original Research 10 October 2010 Pages: 1627 - 1631
Synthesis and antimalarial activity evaluation of some isoquine analogues
Suranjana Bora
Dipak Chetia
Anil Prakash
Original Research 12 October 2010 Pages: 1632 - 1637
Design and synthesis of some novel 3-[5-(4-substituted) phenyl-1,3,4-oxadiazole-2yl]-2-phenylquinazoline-4(3H)-ones as possible anticonvulsant agent
Anjali Gupta
Sushil K. Kashaw
J. P. Stables
Original Research 04 November 2010 Pages: 1638 - 1642
Quantitative structure activity relationship (QSAR) of N ⁶-substituted adenosine receptor agonists as potential antihypertensive agents
Sarvesh Paliwal
Sucheta Das
Shailendra Paliwal
Original Research 04 November 2010 Pages: 1643 - 1649
Comparison between antioxidant activity of 2,5-disubstituted 1,3,4-oxadiazoles containing heteroaromatic ring and aromatic ring at 2nd position
Radhika Maheshwari
Pooja Chawla
Shubhini A. Saraf
Original Research 04 November 2010 Pages: 1650 - 1655
Antidiabetic and antidyslipidemic activities of Cuminum cyminum L. in validated animal models
Rohit Srivsatava
Swayam Prakash Srivastava
Arvind Kumar Srivastava
Original Research 04 November 2010 Pages: 1656 - 1666
Immunosuppressive activity of hexane and ethanolic extracts of Pterospermum acerifolium seeds in BALB/c mice
Manisha Pathak
Nasreen Bano
Shailja Misra-Bhattacharya
Original Research 30 October 2010 Pages: 1667 - 1673
Genomic stability and tissue protection of Clerodendron inerme (L.) Gaertn leaves
Ravindra Kumar Chourasiya
Prateek Kumar Jain
Ram Kishore Agrawal
Original Research 05 November 2010 Pages: 1674 - 1679
MD studies on neuraminidase for probing binding pose of its inhibitors
Swapnil Chavan
Pavan Kare
M. Elizabeth Sobhia
Original Research 11 November 2010 Pages: 1680 - 1686
Appraisal of ozone as biologically active molecule and experimental tool in biomedical sciences
Mmalebuso L. Mokoena
Christiaan B. Brink
Douglas W. Oliver
Original Research 11 November 2010 Pages: 1687 - 1695
Synthesis, anticonvulsant and neurotoxic activity of some new 2,5-disubstituted-1,3,4-oxadiazoles
Neha Jain
Sushil K. Kashaw
Abhishek Soni
Original Research 16 November 2010 Pages: 1696 - 1703
Homology modeling of human CCR2 receptor
Rajesh Singh
M. Elizabeth Sobhia
Original Research 21 November 2010 Pages: 1704 - 1712
QSAR analysis of Mur B inhibitors with antibacterial properties discussing role of physico-chemical parameters
A. K. Srivastava
Vinay Kumar Pathak
Vijay K. Agrawal
Original Research 27 November 2010 Pages: 1713 - 1723
Antihyperglycaemic and aldose reductase inhibitory potential of Acacia catechu hard wood and Tectona grandis leaves
Vikram Bhatia
Swayam P. Srivastava
Arvind K. Srivastava
Original Research 28 November 2010 Pages: 1724 - 1731
Acacia catechu hard wood: potential anti-diabetic cum anti-dyslipidemic
Swayam Prakash Srivastava
Akansha Mishra
Arvind K. Srivastava
Original Research 12 December 2010 Pages: 1732 - 1739