Ethics of Pediatric Drug Research

In this topical collection (18 articles)

1. Editorial

   Creating a New Ethical Climate for Drug Research in Children and Pregnant Women

   Doreen Matsui, Gideon Koren Pages 1-3

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2. Review Article

   Informed Consent in Pediatric Research

   Tom Leibson, Gideon Koren Pages 5-11

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3. 

   Current Opinion

   A Practical Approach to Risk-Benefit Estimation in Pediatric Drug Research

   Gideon Koren Pages 13-16

4. 

   Current Opinion

   The Principle of Equipoise in Pediatric Drug Trials

   Kim Chau, Gideon Koren Pages 17-21

5. 

   Leading Article

   Ethics Review of Pediatric Multi-Center Drug Trials

   Allison C. Needham, Mufiza Z. Kapadia, Martin Offringa Pages 23-30

6. 

   Review Article

   Ethics of Studies of Drugs in Pregnancy

   Doreen Matsui Pages 31-35

7. 

   Current Opinion

   Ethics of Drug Studies in the Newborn

   Robert M. Ward, Catherine M. T. Sherwin Pages 37-42

8. 

   Review Article

   Ethics of Drug Research in the Pediatric Intensive Care Unit

   Niina Kleiber, Krista Tromp, Miriam G. Mooij, Suzanne van de Vathorst… Pages 43-53

9. 

   Current Opinion

   Ethics of Pharmacological Research Involving Adolescents

   Eva Welisch, Luis A. Altamirano-Diaz Pages 55-59

10. 

    Current Opinion

    Ethics in Pharmacologic Research in the Child with a Disability

    Peter Rumney, James A. Anderson, Stephen E. Ryan Pages 61-68

11. 

    Current Opinion

    Ethics of Research in Pediatric Emergency Medicine

    Gal Neuman, Itay Shavit, Doreen Matsui, Gideon Koren Pages 69-76

12. 

    Current Opinion

    The Complexity of Consenting to Clinical Research in Phase I Pediatric Cancer Studies

    Tal Schechter, Ronald Grant Pages 77-81

13. 

    Review Article

    Pediatric Clinical Drug Trials in Low-Income Countries: Key Ethical Issues

    S. M. MacLeod, D. C. Knoppert, M. Stanton-Jean, D. Avard Pages 83-90

14. 

    Review Article

    Ethical Perspectives on Translational Pharmacogenetic Research Involving Children

    Parvaz Madadi Pages 91-95

15. Original Research Article

    A Qualitative Study into Dependent Relationships and Voluntary Informed Consent for Research in Pediatric Oncology

    Sara A. S. Dekking, Rieke van der Graaf… Pages 145-156

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16. 

    Leading Article

    Facilitating Informed Permission/Assent/Consent in Pediatric Clinical Trials

    Susan M. Abdel-Rahman Pages 205-214

17. Current Opinion

    Ethical Considerations for the Participation of Children of Minor Parents in Clinical Trials

    Mary A. Ott, Francis P. Crawley, Xavier Sáez-Llorens, Seth Owusu-Agyei… Pages 215-222

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18. Letter to the Editor

    Clinical Research in Paediatrics: What Can We Do?

    Alessandra Pugi, Valentina Borsi, Alessio Fabbiano, Maria Carmela Leo Pages 255-256

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