Articles

1. Unearthing FLVCR1a: tracing the path to a vital cellular transporter

   • Veronica Fiorito
   • Emanuela Tolosano

   Review Open access 06 April 2024 Article: 166

   

2. CRL4^DCAF13 E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes

   • Peipei Ren
   • Xiaomei Tong
   • Yin-Li Zhang

   Original Article Open access 05 April 2024 Article: 165

   

3. Aberrant splicing of Ca_V1.2 calcium channel induced by decreased Rbfox1 enhances arterial constriction during diabetic hyperglycemia

   • Wei Hou
   • Shumin Yin
   • Juejin Wang

   Original Article Open access 04 April 2024 Article: 164

   

4. iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I

   • Matteo Calligaris
   • Donatella P. Spanò
   • Simone D. Scilabra

   Original Article Open access 04 April 2024 Article: 163

   

5. Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA–protein interactions

   • Andreas Feichtner
   • Florian Enzler
   • Omar Torres-Quesada

   Original Article Open access 03 April 2024 Article: 162

   

6. Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation

   • Remi Marrocco
   • Isabelle Bernard
   • Abdelhadi Saoudi

   Original Article Open access 02 April 2024 Article: 161

   

7. EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells

   • Jasmin Huttunen
   • Niina Aaltonen
   • Ville Paakinaho

   Original Article Open access 02 April 2024 Article: 160

   

8. Peripheral T-cell responses of EphB2- and EphB3-deficient mice in a model of collagen-induced arthritis

   • Sara Montero-Herradón
   • Javier García-Ceca
   • Agustín G. Zapata

   Original Article Open access 01 April 2024 Article: 159

   

9. A novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration

   • Shuzhang Liang
   • Yating Zhou
   • Ruilin Zhang

   Original Article Open access 31 March 2024 Article: 158

   

10. Regulation and function of transposable elements in cancer genomes

    • Michael Lee Jr.
    • Syed Farhan Ahmad
    • Jian Xu

    Review Open access 31 March 2024 Article: 157

    

11. Unraveling the role of Xist in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A

    • Mingming Liang
    • Lichao Zhang
    • Zhanjun Li

    Original Article Open access 29 March 2024 Article: 156

    

12. Aberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse

    • Jin-Wen Kang
    • Jia-Peng He
    • Ren-Wei Su

    Original Article Open access 28 March 2024 Article: 155

    

13. Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury

    • Xujun Peng
    • Huiling Li
    • Dongshan Zhang

    Original Article Open access 28 March 2024 Article: 154

    

14. De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor

    • Yuchen Xu
    • Rui Song
    • Stephen F. Traynelis

    Original Article Open access 28 March 2024 Article: 153

    

15. Macrophage re-programming by JAK inhibitors relies on MAFB

    • Baltasar López-Navarro
    • Miriam Simón-Fuentes
    • Amaya Puig-Kröger

    Original Article Open access 25 March 2024 Article: 152

    

16. Obesogenic diet in pregnancy disrupts placental iron handling and ferroptosis and stress signalling in association with fetal growth alterations

    • Jonas Zaugg
    • Jorge Lopez-Tello
    • Amanda N. Sferruzzi-Perri

    Original Article Open access 25 March 2024 Article: 151

    

17. The exon junction complex is required for DMD gene splicing fidelity and myogenic differentiation

    • Dylan Da Cunha
    • Julie Miro
    • Sylvie Tuffery-Giraud

    Original Article Open access 21 March 2024 Article: 150

    

18. cGAS-STING pathway mediates activation of dendritic cell sensing of immunogenic tumors

    • Guohao Li
    • Xiangqian Zhao
    • Qi Chen

    Review Open access 21 March 2024 Article: 149

    

19. The antiviral response triggered by the cGAS/STING pathway is subverted by the foot-and-mouth disease virus proteases

    • Miguel Ángel Sanz
    • Miryam Polo
    • Margarita Sáiz

    Original Article Open access 20 March 2024 Article: 148

    

20. Neonatal GABAergic transmission primes vestibular gating of output for adult spatial navigation

    • Qiufen Jiang
    • Kenneth Lap-Kei Wu
    • Ying-Shing Chan

    Original Article Open access 19 March 2024 Article: 147

    

21. Single-cell analysis of age-related changes in leukocytes of diabetic mouse hindpaws

    • James M. Nichols
    • Hoang Vu Pham
    • Andrew J. Shepherd

    Original Article Open access 19 March 2024 Article: 146

    

22. USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells

    • Janardhan Keshav Karapurkar
    • Jencia Carminha Colaco
    • Suresh Ramakrishna

    Original Article Open access 18 March 2024 Article: 145

    

23. Molecular engineering of a spheroid-penetrating phage nanovector for photodynamic treatment of colon cancer cells

    • Eleonora Turrini
    • Luca Ulfo
    • Alberto Danielli

    Original Article Open access 17 March 2024 Article: 144

    

24. YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression

    • Xuan Li
    • Hongguang Zhong
    • Jun Deng

    Original Article Open access 17 March 2024 Article: 143

    

25. Txnip regulates the Oct4-mediated pluripotency circuitry via metabolic changes upon differentiation

    • Sojung Kwak
    • Cho Lok Song
    • Jungwoon Lee

    Original Article Open access 15 March 2024 Article: 142

    

26. Lamin B1 curtails early human papillomavirus infection by safeguarding nuclear compartmentalization and autophagic capacity

    • Freya Molenberghs
    • Marlies Verschuuren
    • Winnok H. De Vos

    Original Article Open access 14 March 2024 Article: 141

    

27. High-content method for mechanosignaling studies using IsoStretcher technology and quantitative Ca²⁺ imaging applied to Piezo1 in cardiac HL-1 cells

    • Anna-Lena Merten
    • Ulrike Schöler
    • Sebastian Schürmann

    Original Article Open access 14 March 2024 Article: 140

    

28. A novel mouse model for N-terminal truncated Aβ2-x generation through meprin β overexpression in astrocytes

    • Fred Armbrust
    • Kira Bickenbach
    • Christoph Becker-Pauly

    Original Article Open access 13 March 2024 Article: 139

    

29. CircAKT3 alleviates postoperative cognitive dysfunction by stabilizing the feedback cycle of miR-106a-5p/HDAC4/MEF2C axis in hippocampi of aged mice

    • Xuan Wang
    • Xiaole Tang
    • Ailin Luo

    Original Article Open access 13 March 2024 Article: 138

    

30. Deubiquitinase UCHL1 promotes angiogenesis and blood–spinal cord barrier function recovery after spinal cord injury by stabilizing Sox17

    • Jiaxing Wang
    • Chengyue Ji
    • Weihua Cai

    Original Article Open access 13 March 2024 Article: 137

    

31. The first A-to-I RNA editome of hemipteran species Coridius chinensis reveals overrepresented recoding and prevalent intron editing in early-diverging insects

    • Yuange Duan
    • Ling Ma
    • Hu Li

    Original Article Open access 13 March 2024 Article: 136

    

32. Role of HCN channels in the functions of basal ganglia and Parkinson’s disease

    • Zeng-Xin Qi
    • Qi Yan
    • Qian-Xing Zhuang

    Review Open access 13 March 2024 Article: 135

    

33. The Janus-faced functions of Apolipoproteins L in membrane dynamics

    • Etienne Pays

    Visions and reflections Open access 13 March 2024 Article: 134

    

34. PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway

    • Qiao-qing Shi
    • Yong-hong Huang
    • Xiao-yan Zhou

    Original Article Open access 13 March 2024 Article: 133

    

35. Crosstalk between purinergic receptor P2Y₁₁ and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages

    • Dominik Klaver
    • Hubert Gander
    • Martin Thurnher

    Original Article Open access 13 March 2024 Article: 132

    

36. Glymphatic-lymphatic coupling: assessment of the evidence from magnetic resonance imaging of humans

    • Geir Ringstad
    • Per Kristian Eide

    Review Open access 13 March 2024 Article: 131

    

37. ALKBH1 promotes HIF-1α-mediated glycolysis by inhibiting N-glycosylation of LAMP2A

    • Yanyan Liu
    • Mengmeng Li
    • Qinghua Zhou

    Original Article Open access 12 March 2024 Article: 130

    

38. Unraveling the molecular interactions between α7 nicotinic receptor and a RIC3 variant associated with backward speech

    • Aditi Pradhan
    • Hayley Mounford
    • Dianne F. Newbury

    Original Article Open access 12 March 2024 Article: 129

    

39. Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model

    • Zhixiong Zhang
    • Rui Wang
    • Guanghui Wang

    Original Article Open access 12 March 2024 Article: 128

    

40. Lipid homeostasis is essential for oogenesis and embryogenesis in the silkworm, Bombyx mori

    • Fangying Yang
    • Xiaoyan Xu
    • Anjiang Tan

    Original Article Open access 12 March 2024 Article: 127

    

41. Role of the GLP2–Wnt1 axis in silicon-rich alkaline mineral water maintaining intestinal epithelium regeneration in piglets under early-life stress

    • Jian Chen
    • Xue-Yan Dai
    • Jin-Long Li

    Original Article Open access 12 March 2024 Article: 126

    

42. Vascular ATGL-dependent lipolysis and the activation of cPLA₂–PGI₂ pathway protect against postprandial endothelial dysfunction

    • M. Sternak
    • M. Stojak
    • S. Chlopicki

    Original Article Open access 12 March 2024 Article: 125

    

43. MSCs alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of macrophages in mouse lung organoid–macrophage model

    • Jiaqi Zhu
    • Jiahang Zhou
    • Hongcui Cao

    Original Article Open access 11 March 2024 Article: 124

    

44. PRMT5-mediated homologous recombination repair is essential to maintain genomic integrity of neural progenitor cells

    • Ya-Jun Wang
    • Jian-Bo Cao
    • Xiao-Juan Zhu

    Original Article Open access 08 March 2024 Article: 123

    

45. Neutrophil extracellular traps mediate cardiomyocyte ferroptosis via the Hippo–Yap pathway to exacerbate doxorubicin-induced cardiotoxicity

    • Peng Zhao
    • You Li
    • Jiawei Tian

    Original Article Open access 08 March 2024 Article: 122

    

46. LncRNA LUESCC promotes esophageal squamous cell carcinoma by targeting the miR-6785-5p/NRSN2 axis

    • Song-tao Xue
    • Shi-qiang Cao
    • Bin Zheng

    Original Article Open access 08 March 2024 Article: 121

    

47. The role of fatty acid metabolism in acute lung injury: a special focus on immunometabolism

    • Xiao Lu
    • Guorui Li
    • Qing Geng

    Review Open access 08 March 2024 Article: 120

    

48. Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors

    • Yu Jiang
    • Lulu Hu
    • Caiping Du

    Original Article Open access 08 March 2024 Article: 119

    

49. Tektin bundle interacting protein, TEKTIP1, functions to stabilize the tektin bundle and axoneme in mouse sperm flagella

    • Xin-Yan Geng
    • Hui-Juan Jin
    • Su-Ren Chen

    Original Article Open access 07 March 2024 Article: 118

    

50. The genome of Haberlea rhodopensis provides insights into the mechanisms for tolerance to multiple extreme environments

    • Saurabh Gupta
    • Veselin Petrov
    • Tsanko Gechev

    Original Article Open access 05 March 2024 Article: 117