1. Overview of protein aggregation in single, double, and triple neurodegenerative brain amyloidoses

   • John Q. Trojanowski
   • Mark P. Mattson

   OriginalPaper Pages: 1 - 5

2. Huntington’s Disease

   • Marcy E. MacDonald
   • Silvia Gines
   • Vanessa C. Wheeler

   OriginalPaper Pages: 7 - 20

3. Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer’s and Parkinson’s diseases

   • Makoto Hashimoto
   • Edward Rockenstein
   • Eliezer Masliah

   OriginalPaper Pages: 21 - 35

4. Tau protein in familial and sporadic diseases

   • Despina Yancopoulou
   • Maria Grazia Spillantini

   OriginalPaper Pages: 37 - 48

5. Interactions of amyloidogenic proteins

   • Benoit I. Giasson
   • Virginia M. Y. Lee
   • John Q. Trojanowski

   OriginalPaper Pages: 49 - 58

6. Protein accumulation in traumatic brain injury

   • Douglas H. Smith
   • Kunihiro Uryu
   • Tracy K. McIntosh

   OriginalPaper Pages: 59 - 72

7. The unfolded protein response in protein aggregating diseases

   • Alexander Gow
   • Ramaswamy Sharma

   OriginalPaper Pages: 73 - 94

8. Role for the ubiquitin-proteasome system in Parkinson’s disease and other neurodegenerative brain amyloidoses

   • Darren J. Moore
   • Valina L. Dawson
   • Ted M. Dawson

   OriginalPaper Pages: 95 - 108

9. Perturbed signal transduction in neurodegenerative disorders involving aberrant protein aggregation

   • Mark P. Mattson
   • Michael Sherman

   OriginalPaper Pages: 109 - 131

10. Making yeast tremble

    • Michael Y. Sherman
    • Paul J. Muchowski

    OriginalPaper Pages: 133 - 146