1. QTc interval analysis—an ever-evolving endeavor

   • Peter L. Bonate

   Editorial 07 April 2021 Pages: 183 - 186

2. Detection and impact of hysteresis when evaluating a drug’s QTc effect using concentration-QTc analysis

   • Georg Ferber
   • Borje Darpo
   • Jiang Liu

   Original Paper 28 October 2020 Pages: 187 - 202

   

3. Concentration–QTc analysis for single arm studies

   • Yasushi Orihashi
   • Shoichi Ohwada
   • Yuji Kumagai

   Original Paper 29 January 2021 Pages: 203 - 211

   

4. PK/PD modeling of a clazosentan thorough QT study with hysteresis in concentration-QT and RR-QT

   • Andrea Henrich
   • Pierre-Eric Juif
   • Andreas Krause

   Original Paper 02 January 2021 Pages: 213 - 224

   

5. Modeling the acute effects of exercise on glucose dynamics in healthy nondiabetic subjects

   • Spencer Frank
   • Abdulrahman Jbaily
   • Andrew J. Szeri

   Original Paper 04 January 2021 Pages: 225 - 239

   

6. Improved numerical stability for the bounded integer model

   • Sebastian Ueckert
   • Mats O. Karlsson

   Original Paper Open access 26 November 2020 Pages: 241 - 251

   

7. A pharmacodynamic model of tidal volume and inspiratory sevoflurane concentration in children during spontaneous breathing

   • Pyoyoon Kang
   • Ji-Hyun Lee
   • Hee-Soo Kim

   Original Paper 02 January 2021 Pages: 253 - 259

   

8. Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women

   • Wojciech Krzyzanski
   • Mark A. Milad
   • William J. Jusko

   Original Paper Open access 03 January 2021 Pages: 261 - 272

   

9. A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer

   • Yesenia L. Franco
   • Vidya Ramakrishnan
   • Sihem Ait-Oudhia

   Original Paper 03 January 2021 Pages: 273 - 293

   

10. Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates

    • Vittal Shivva
    • Martin Fink
    • Philip J. Lowe

    Original Paper 03 January 2021 Pages: 295 - 303

    

11. Do epoch lengths of hypnotic depth indicators affect estimated of blood-brain equilibration rate constants of propofol?

    • Kyung Mi Kim
    • Sookyung Park
    • Ji-Yeon Bang

    Original Paper 07 January 2021 Pages: 305 - 317