1. Announcement

   Announcement 01 June 1999 Pages: i - i

2. Cellular Pharmacokinetics: Effects of Cytoplasmic Diffusion and Binding on Organ Transit Time Distribution

   • Michael Weiss

   OriginalPaper 01 June 1999 Pages: 233 - 256

3. A Combined Specific Target Site Binding and Pharmacokinetic Model to Explore the Non-linear Disposition of Draflazine

   • Eric Snoeck
   • Philippe Jacqmin
   • Meindert Danhof

   OriginalPaper 01 June 1999 Pages: 257 - 281

4. Analysis of Antiplatelet Effect of Ticlopidine In Humans: Modeling Based on Irreversible Inhibition of Platelet Precursors in Bone Marrow

   • Masataka Katashima
   • Yasuhiko Yamada
   • Tatsuji Iga

   OriginalPaper 01 June 1999 Pages: 283 - 296

5. Predicting the Time Needed to Achieve Steady State If Absorption and Elimination Constants Are Equal

   • Júlia Singer
   • László Vereczkey

   OriginalPaper 01 June 1999 Pages: 297 - 300

6. Application of a Combined “Effect Compartment/Indirect Response Model” to the Central Nervous System Effects of Tiagabine in the Rat

   • Adriaan Cleton
   • Henrik J. M. M. de Greef
   • Meindert Danhof

   OriginalPaper 01 June 1999 Pages: 301 - 323

7. Rapid Attainment of Steady-State Plasma Drug Concentrations Within Precise Limits in Multicompartment Mammillary Systems

   • Ben Korman
   • Les S. Jennings

   OriginalPaper 01 June 1999 Pages: 325 - 328

8. A Compartmental Analysis of the Pharmacokinetics of Propofol in Sheep

   • Guy L. Ludbrook
   • Richard N. Upton
   • Alison Martinez

   OriginalPaper 01 June 1999 Pages: 329 - 338

9. Course Announcement

   Announcement 01 June 1999 Pages: 339 - 341