Volume 39, Issue 4

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December 2020

Mutant KRAS: Hidden Secrets of an Oncogene

Issue Editor:

Jozsef Timar

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19 articles in this issue

Biography—József Tímár

Announcement 21 November 2020 Pages: 1015 - 1015
Guest editorial/preface
József Tímár
EditorialNotes 16 September 2020 Pages: 1017 - 1017
A “New Radiation”—shining light on cancer
Gregory W. Auner
Michelle A. Brusatori
Commentary 13 November 2020 Pages: 1019 - 1020
Part of 1 collection:

Cancer and Metastasis Editorials and Commentaries
Metastasis is a highly stressful process
Alejandro D. Campos
Sara M. Weis
David A. Cheresh
Commentary 06 November 2020 Pages: 1021 - 1022
Part of 1 collection:

Cancer and Metastasis Editorials and Commentaries
A perspective on the early days of RAS research
Robin A. Weiss
Editorial Open access 29 July 2020 Pages: 1023 - 1028
Part of 1 collection:

Cancer and Metastasis Editorials and Commentaries
Molecular epidemiology and diagnostics of KRAS mutations in human cancer
Jozsef Timar
Karl Kashofer
ReviewPaper Open access 29 July 2020 Pages: 1029 - 1038
Splice variants of RAS—translational significance
Erzsébet Rásó
ReviewPaper Open access 08 August 2020 Pages: 1039 - 1049
The effects of mutant Ras proteins on the cell signalome
Tamás Takács
Gyöngyi Kudlik
Virag Vas
ReviewPaper Open access 09 July 2020 Pages: 1051 - 1065
Novel regulation of Ras proteins by direct tyrosine phosphorylation and dephosphorylation
László Buday
Virág Vas
ReviewPaper Open access 16 September 2020 Pages: 1067 - 1073
Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery
Gyula Pálfy
Dóra K. Menyhárd
András Perczel
ReviewPaper Open access 20 August 2020 Pages: 1075 - 1089
Structure-based inhibitor design of mutant RAS proteins—a paradigm shift
Kinga Nyíri
Gergely Koppány
Beáta G. Vértessy
ReviewPaper Open access 26 July 2020 Pages: 1091 - 1105
Small molecule inhibitors of RAS proteins with oncogenic mutations
Zoltán Orgován
György M. Keserű
ReviewPaper Open access 07 August 2020 Pages: 1107 - 1126
K-Ras prenylation as a potential anticancer target
Marcell Baranyi
László Buday
Balázs Hegedűs
ReviewPaper Open access 10 June 2020 Pages: 1127 - 1141
Current therapy of advanced colorectal cancer according to RAS/RAF mutational status
Gábor Lakatos
Claus-Henning Köhne
György Bodoky
ReviewPaper 09 July 2020 Pages: 1143 - 1157
Current therapy of KRAS-mutant lung cancer
Aron Ghimessy
Peter Radeczky
Zsolt Megyesfalvi
ReviewPaper Open access 16 June 2020 Pages: 1159 - 1177
Gastric cancer: a comprehensive review of current and future treatment strategies
Rachel E. Sexton
Mohammed Najeeb Al Hallak
Asfar S. Azmi
Non-Thematic Review 07 September 2020 Pages: 1179 - 1203
Platelets in aging and cancer—“double-edged sword”
Alessandra V. S. Faria
Sheila S. Andrade
Gwenny M. Fuhler
Non-Thematic Review Open access 01 September 2020 Pages: 1205 - 1221
Molecular mediators of peritoneal metastasis in pancreatic cancer
Leela Rani Avula
Brendan Hagerty
Christine Alewine
Non-Thematics Review Open access 11 August 2020 Pages: 1223 - 1243
Rho GTPases in cancer radiotherapy and metastasis
Rui-Jie Zeng
Chun-Wen Zheng
En-Min Li
Non-Thematics Review 08 August 2020 Pages: 1245 - 1262

Volume 39, Issue 4

Biography—József Tímár

Guest editorial/preface

A “New Radiation”—shining light on cancer

Metastasis is a highly stressful process

A perspective on the early days of RAS research

Molecular epidemiology and diagnostics of KRAS mutations in human cancer

Splice variants of RAS—translational significance

The effects of mutant Ras proteins on the cell signalome

Novel regulation of Ras proteins by direct tyrosine phosphorylation and dephosphorylation

Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery

Structure-based inhibitor design of mutant RAS proteins—a paradigm shift

Small molecule inhibitors of RAS proteins with oncogenic mutations

K-Ras prenylation as a potential anticancer target

Current therapy of advanced colorectal cancer according to RAS/RAF mutational status

Current therapy of KRAS-mutant lung cancer

Gastric cancer: a comprehensive review of current and future treatment strategies

Platelets in aging and cancer—“double-edged sword”

Molecular mediators of peritoneal metastasis in pancreatic cancer

Rho GTPases in cancer radiotherapy and metastasis

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