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Phase-field model for the morphology of monolayer lipid domains

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Abstract.

Phase-separated domains exist in multicomponent lipid monolayers and bilayers. We present here a phase-field model that takes into account the competition between lipid dipole-dipole interactions and line tension to define the domain morphology. A dynamic equation for the phase-field is solved numerically showing stationary non-circular shapes like starfish shapes. This phase-field model could be applied to study the dynamic properties of complex problems like phase segregation in pulmonary surfactant membranes and films.

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Authors and Affiliations

  1. Department of Cell and Developmental Biology, Center for Genomic Regulation (CRG) and UPF, Barcelona, Spain

    F. Campelo

  2. Departament d’Estructura i Constituents de la Matèria, Universitat de Barcelona, E-08028, Barcelona, Spain

    F. Campelo & A. Hernández-Machado

  3. Departamento de Bioquímica, Facultad de Biología, Universidad Complutense, 28040, Madrid, Spain

    A. Cruz & J. Pérez-Gil

  4. Instituto de Ciencia de Materiales de Madrid (CSIC), 28049, Madrid, Spain

    L. Vázquez

Authors
  1. F. Campelo
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  2. A. Cruz
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  3. J. Pérez-Gil
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  4. L. Vázquez
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  5. A. Hernández-Machado
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Correspondence to F. Campelo.

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Campelo, F., Cruz, A., Pérez-Gil, J. et al. Phase-field model for the morphology of monolayer lipid domains. Eur. Phys. J. E 35, 49 (2012). https://doi.org/10.1140/epje/i2012-12049-2

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  • DOI: https://doi.org/10.1140/epje/i2012-12049-2

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