Abstract
Matrix assisted laser desorption/ionization (MALDI) measurements with femtosecond laser pulses at a central wavelength of 400 are presented. The examined analyte is potassium adapted angiotensine II whereby the matrix is a combination of sinapic acid and α-cyano-4-hydroxycinamic acid. Pulse energy dependent measurements are performed in order to investigate the MALDI processes for the obtained potassium adapted angiotensine II complexes. The results show the higher stabilization tendency of the potassium adapted angiotensine II which could be used to bring very fragile non-stable macromolecules into the gas phase. The outlined approach is an attempt to explain the underlying MALDI process by focusing on the mass spectra of potassium adapted angiotensine II.
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References
M. Karas, D. Hillenkamp, Anal. Chem. 57, 2935 (1987)
M. Karas et al., Int. J. Mass Spectrom. Ion Proc. 78, 53 (1987)
M. Karas, F. Hillenkamp, Anal. Chem. 60, 2299 (1988)
D.C. Schriemer, L. Li, Anal. Chem. 68, 2721 (1996)
S. Berkenkamp et al., Science 281, 337 (1998)
S.D. Hanton et al., Chem. Rev. 28, 4562 (2001)
R. Knochenmuss et al., J. Phys. Chem. B 109, 22947 (2005)
L.V. Zigilei, E. Leveugle, Chem. Rev. 103, 321 (2003)
M. Karas, R. Krüger, Chem. Rev. 103, 427 (2003)
R. Knochenmuss, Analyst 131, 966 (2006)
F.H. Jassim, D.S. Marynick, J. Phys. Chem. A 110, 3820 (2006)
M.W. Little et al., J. Mass Spectrom. 38, 772 (2003)
B.H. Wang et al., J. Am. Soc. Mass Spectrom. 4, 393 (1993)
P. Demirev et al., Rapid Commun. Mass Spectrom. 6, 187 (1992)
M.R. Papantonakis et al., J. Mass Spectrom. 37, 639 (2002)
H. Dau, M. Haumann, Science 312, 1471 (2006)
R. Mitrić et al., J. Chem. Phys. 127, 134301 (2007)
R. Antoine et al., J. Phys. Chem. 7, 524 (2006)
P.C. Liao, J. Alliston, J. Mass Spectrom. 30, 408 (1995)
S. North et al., Rapid Commun. Mass Spectrom. 11, 1635 (1997)
J. Zhang et al., J. Phys. Chem. A 107, 6891 (2003)
D.A. Allwood et al., Rapid. Commun. Mass Spetrom. 10, 1575 (1996)
K. Breuker et al., Int. J. Mass Spectrom. 226, 211 (2003)
R.S. Judson, H. Rabitz, Phys. Rev. Lett. 68, 1500 (1992)
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Wichmann, J., Lupulescu, C., Wöste, L. et al. Matrix assisted laser desorption/ionization of potassium adapted angiotensine II using femtosecond laser pulses. Eur. Phys. J. D 52, 151–154 (2009). https://doi.org/10.1140/epjd/e2009-00012-2
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DOI: https://doi.org/10.1140/epjd/e2009-00012-2