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Visualizing the Laboratory Mouse: Capturing Phenotype Information

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Abstract

A concerted effort to develop myriad new phenotypic alleles through mutagenesis programs presents new challenges for the biomedical community and for the informatics infrastructure needed to support this work. To handle and co-ordinate large programs of treatment, breeding, and sequential or longitudinal testing for a variety of obvious and subtle traits requires sophisticated data management software. Further, trait analyses, heritability testing, and animal availability and status must be captured and disseminated to the wider community. The Mouse Genome Database (MGD) will serve as the central integration point for the various mutagenesis programs, registering new alleles, providing accession identifiers, and capturing phenotypic descriptions. In addition, MGD will provide public access to unified searches over all alleles with links to the centres of origin for detailed testing data.

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Authors and Affiliations

  1. Informatics Group, Mammalian Genetics Unit & UK Mouse Genome Centre, UK

    Mark Strivens

  2. The Jackson Laboratory, 600 Main Street, ME, USA

    Janan T. Eppig

  3. Lexicon Genetics, Inc., 8800 Technology Forest Place, TX, USA

    Janan T. Eppig

Authors
  1. Mark Strivens
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  2. Janan T. Eppig
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Strivens, M., Eppig, J.T. Visualizing the Laboratory Mouse: Capturing Phenotype Information. Genetica 122, 89–97 (2004). https://doi.org/10.1007/s10709-004-1435-7

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  • DOI: https://doi.org/10.1007/s10709-004-1435-7

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