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A New Neolignan from the Aerial Parts of Prunella vulgaris var. lilacina

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Chemistry of Natural Compounds Aims and scope

Prunella vulgaris is known to contain pentacyclic triterpenoids, flavonoids, phenolic compounds, and steroids. Among the triterpenoids, the oleanane-type, ursane-type, and lupane-type triterpenoids have been known to be predominant. Our phytochemical study led to the isolation of a new neolignan, 9′-O-butyl dehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside (1), together with four known compounds, astragalin (2), benzyl-O-β-D-glucopyranoside (3), paeonoside (4), and 4-hydroxybenzoic acid (5). It is noteworthy that all the isolated compounds are reported for the first time from the genus Prunella.

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References

  1. J. Duke, Handbook of Edible Weeds, CRC Press, London, 2001, 158 pp.

  2. S. Foster and C. Hobbs, A Field Guide to Western Medicinal Plants and Herbs, Houghton Mifflin Harcourt, Boston, 2002, 231 pp.

  3. F. Liu and T. B. Na, Life Sci., 165, 725 (2000).

    Article  Google Scholar 

  4. S. Y. Ryu, M. H. Oak, S. K. Yoon, D. I. Cho, G. S.Yoo, T. S. Kim, and K. M. Kim, Planta Med., 66, 358 (2000).

    Article  CAS  PubMed  Google Scholar 

  5. H. I. Kim, F. S. Quan, J. E. Kim, N. R. Lee, H. J. Kim, S. J. Jo, C. M. Lee, D. S. Jang, and K. S. Inn, Biochem. Biophys. Res. Commun., 451, 282 (2014).

    Article  CAS  PubMed  Google Scholar 

  6. G. Kwon, H. J. Kim, S. J. Park, H. E. Lee, H. Woo, Y. J. Ahn, Q. Gao, J. H. Cheong, D. S. Jang, and J. H. Ryu, Life Sci., 101, 73 (2014).

    Article  CAS  PubMed  Google Scholar 

  7. K. Hisashi, T. Hideo, and S. Shigeki, Phytochemistry, 26, 1107 (1987).

    Article  Google Scholar 

  8. I. K. Lee, D. H. Kim, S. Y. Lee, K. R. Kim, S. U. Choi, J. K. Hong, J. H. Lee, Y. H. Park, and K. R. Lee, Arch. Pharm. Res., 31, 1578 (2008).

    Article  CAS  PubMed  Google Scholar 

  9. K. Hisashi, S. Noriko, H. Akiko, and O.Haruo, Phytochemistry, 29, 2351 (1990).

    Article  Google Scholar 

  10. H. Lou, S. Zheng, T. Li, J. Zhang, Y. Fei, X. Hao, G. Liang, and W. Pan, Org. Lett., 16, 2696 (2014).

    Article  CAS  PubMed  Google Scholar 

  11. T. Tanaka, T. Nakashima, T. Ueda, K. Tomii, and I. Kouno, Chem. Pharm. Bull., 55, 899 (2007).

    Article  CAS  PubMed  Google Scholar 

  12. L. Xiang, C. Zhu, Y. Li, Y. Tian, S. Lin, S. Yuan, J. Hu, Q. Hou, N. Chen, Y. Yang, and J. Shi, J. Nat. Prod., 74, 1188 (2011).

    Article  Google Scholar 

  13. J. Lee, D. Kim, J. Choi, H. Choi, J. Ryu, J. Jeong, E. Park, S. Kim, and S. Kim, J. Biol. Chem., 287, 8839 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. H. Xiao, Y. Dai, M. Wong, and X. Yao, Fitoterapia, 94, 29 (2014).

    Article  CAS  PubMed  Google Scholar 

  15. D. V. Tarbeeva, S. A. Fedoreyev, M. V. Veselova, A. I. Kalinovskiy, L. D. Seletskaya, T. I. Mazurok, and V. P. Bulgakov, Nat. Prod. Commun., 8, 1419 (2013).

    CAS  PubMed  Google Scholar 

  16. T. Deyama, T. Ikawa, S. Kitagawa, and S. Nishibe, Chem. Pharm. Bull., 35, 803 (1987).

    Google Scholar 

  17. Y. Yoneda, K. Krainz, F. Liebner, A. Potthast, T. Rosenau, M. Karakawa, and F. Nakatsubo, Eur. J. Org. Chem., 2008, 475 (2008).

    Article  Google Scholar 

  18. M. Jin, C. Zhang, T. Zheng, D. Yao, L. Shen, J. Luo, Z. Jiang, J. Ma, X. J. Jin, J. Cui, J. J. Lee, and G. Li, Nat. Prod. Res., 28, 1813 (2014).

    Article  CAS  PubMed  Google Scholar 

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Acknowledgment

This research was supported by Duksung Women′s University research grant in 2015.

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Authors and Affiliations

  1. College of Pharmacy, Duksung Women′s University, Seoul, 132-714, South Korea

    Changyeol Lee & Sang Hee Shim

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  1. Changyeol Lee
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  2. Sang Hee Shim
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Correspondence to Sang Hee Shim.

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Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2017, pp. 24–26.

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Lee, C., Shim, S.H. A New Neolignan from the Aerial Parts of Prunella vulgaris var. lilacina . Chem Nat Compd 53, 24–27 (2017). https://doi.org/10.1007/s10600-017-1902-x

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  • DOI: https://doi.org/10.1007/s10600-017-1902-x

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