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Assessment of global function of left ventricle with dual-source CT in patients with severe arrhythmia: a comparison with the use of two-dimensional transthoracic echocardiography

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Abstract

To evaluate the agreement between dual-source computed tomography (DSCT) and two-dimensional transthoracic echocardiography (2D-TTE) with respect to the assessment of global left ventricular (LV) function in patients with severe arrhythmia. With 2D-TTE serving as the reference method, we performed both DSCT and 2D-TTE, at an interval of less than 2 days, in 54 patients with severe arrhythmia (average heart rate difference >30 beats per min) before open heart surgery for evaluation of valvular heart disease (VHD) and coronary artery disease. DSCT was performed using retrospective electrocardiography (ECG) without dose modulation. Ten phases of the cardiac cycle were analyzed for identification of end-diastolic and end-systolic phases with ECG-editing. Pearson’s correlation coefficient (r) and Bland–Altman analysis were used to determine agreement for parameters of LV global function. Correlation between DSCT and 2D-TTE measurements was good or excellent in terms of the values of the LV ejection fraction (51.0 ± 11.4% vs. 55.8 ± 11.6%; r = 0.8), LV end-diastolic volume (179.5 ± 98.6 ml vs. 152.1 ± 73.8 ml; r = 0.95), LV end-systolic volume (90.7 ± 60.7 ml vs. 69.1 ± 46.8 ml; r = 0.90), and LV stroke volume (89.0 ± 48.1 ml vs. 82.9 ± 37.3 ml; r = 0.89). Left ventricular ejection fraction measured using DSCT was less than that measured using 2D-TTE by an average of −4.8 ± 7.3%. Dual-source CT with ECG editing can provide results comparable to those of 2D-TTE for assessment of LV global function in patients with severe arrhythmia.

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Abbreviations

AF:

Atrial fibrillation

DSCT:

Dual-source multidetector computed tomography

ECG:

Electrocardiography

EF:

Ejection fraction

LV:

Left ventricle

LVEF:

Left ventricular ejection fraction

LVEDV:

Left ventricular end-diastolic volume

LVESV:

Left ventricular end-systolic volume

MDCT:

Multi-detector computed tomography

MRI:

Magnetic resonance imaging

2D:

Two dimensional

2D-TTE:

Two dimensional transthoracic echocardiography

VHD:

Valvular heart disease

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Acknowledgments

This work was supported by Konkuk University in 2010. The authors would like to thank the CT technologists, the radiology department nursing staff, the cardiology department staff physicians and the residents in the Division of Thoracic Surgery at the Konkuk University Hospital.

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Authors and Affiliations

  1. Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, South Korea

    Song Soo Kim

  2. Departments of Radiology, Konkuk University Hospital, Konkuk University School of Medicine, 4-12 Hwayang-dong, Gwangjin-gu, Seoul, 143-729, South Korea

    Sung Min Ko

  3. Department of Thoracic surgery, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, South Korea

    Meong Gun Song & Joon Suk Kim

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  1. Song Soo Kim
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Correspondence to Sung Min Ko.

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Kim, S.S., Ko, S.M., Song, M.G. et al. Assessment of global function of left ventricle with dual-source CT in patients with severe arrhythmia: a comparison with the use of two-dimensional transthoracic echocardiography. Int J Cardiovasc Imaging 26 (Suppl 2), 213–221 (2010). https://doi.org/10.1007/s10554-010-9692-2

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  • DOI: https://doi.org/10.1007/s10554-010-9692-2

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