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Retrospective, matched case-control study comparing the oncologic outcomes between laparoscopic surgery and open surgery in patients with right-sided colon cancer

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Abstract

Purpose

The short- and long-term outcomes of laparoscopic surgery for right-sided colon cancer remain largely uninvestigated. This study was undertaken to compare the morbidity and mortality after either a laparoscopic right hemicolectomy (LRHC) or an open right hemicolectomy (ORHC) for this type of tumor.

Methods

The study group included 100 patients who underwent an LRHC and 100 patients who underwent an ORHC for right-sided colon cancer from 1990 through 2004. The two groups were retrospectively well matched with respect to sex, age (±5 years), and pathological tumor-node-metastasis (TNM) stage.

Results

The median follow-up period was 83 months in the LRHC group and 105 months in the ORHC group. The LRHC group had a lower volume of intraoperative bleeding (P < 0.001), a lower rate of wound infection (P = 0.019) or postoperative intestinal obstruction (P = 0.013), and a shorter hospital stay (P < 0.001) than the ORHC group. The rate of recurrence did not differ significantly between the LRHC group (19%) and the ORHC group (22%). In patients with TNM stage I or II, the disease-free survival (DFS) rate (94.9% vs 95.1%) and overall survival (OS) rate (95.8% vs 95.0%) did not differ significantly between the two groups. A similar tendency was observed in patients with stage III with the rates for DFS (71.3% vs 60.4%) and OS (73.6% vs 64.1%), respectively.

Conclusions

An LRHC for right-sided colon cancer has the advantage over an ORHC of better short-term outcomes, and both groups have similar long-term oncologic outcomes. An LRHC is thus an acceptable alternative to an ORHC for the treatment of this type cancer.

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Authors and Affiliations

  1. Department of Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa, 228-8555, Japan

    Takatoshi Nakamura, Wataru Onozato, Masanori Naito, Takeo Sato, Heita Ozawa, Kazuhiko Hatate, Atsushi Ihara & Masahiko Watanabe

  2. Department of Clinical Research Laboratory (Pathology Division), National Hospital Organization, Sagamihara Hospital, Sagamihara, Kanagawa, Japan

    Hiroyuki Mitomi

Authors
  1. Takatoshi Nakamura
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  2. Wataru Onozato
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  3. Hiroyuki Mitomi
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  4. Masanori Naito
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  5. Takeo Sato
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  6. Heita Ozawa
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  7. Kazuhiko Hatate
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  8. Atsushi Ihara
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  9. Masahiko Watanabe
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Nakamura, T., Onozato, W., Mitomi, H. et al. Retrospective, matched case-control study comparing the oncologic outcomes between laparoscopic surgery and open surgery in patients with right-sided colon cancer. Surg Today 39, 1040–1045 (2009). https://doi.org/10.1007/s00595-009-4011-z

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  • DOI: https://doi.org/10.1007/s00595-009-4011-z

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