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Clinicopathologic characteristics of paranasal sinus fungus ball: retrospective, multicenter study in Korea

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

Fungus ball (FB) is the most common type of fungal rhinosinusitis and the prevalence of FB has increased over the past 10 years. The aim of this study was to compare the clinical characteristics of Korean adult patients with FB and chronic rhinosinusitis (CRS) without FB.

Methods

We retrospectively analyzed data on 1362 patients (147 FB and 1215 CRS) who underwent endoscopic sinus surgery at nine Korean medical centers in 2005, 2010, and 2016. We evaluated the prevalence of FB and compared the clinical characteristics of FB and CRS. Medical records, computed tomography (CT) findings, atopic status, concomitant diseases, tissue, and blood eosinophil count were assessed.

Results

The prevalence of FB was significantly higher in 2016 (15.9%) than in the other years (7.8% in 2005 and 7.5% in 2010). The FB patients were more likely to be female, older, have unilateral disease and less likely to have allergy compared to the CRS patients. The most common main complaint related to CRS and FB was nasal obstruction. CT determined that unilateral disease and maxillary sinus dominancy were common in patients with FB. The incidence of concomitant diseases was much higher in FB, with lower tissue and blood eosinophilia.

Conclusion

FB is commonly encountered in older women with the increased prevalence. FB had a different clinical presentation, radiological findings, and prognosis than CRS. Further studies are needed to understand the pathophysiologic mechanisms underlying the development of FB.

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Author information

Author notes

  1. Dae Woo Kim and Yong Min Kim have contributed equally to this paper.

Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea

    Dae Woo Kim

  2. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Chungnam National University, Daejeon, South Korea

    Yong Min Kim

  3. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, South Korea

    Jin-Young Min

  4. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Seoul National University, Seoul, South Korea

    Jeong-Whun Kim

  5. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Konkuk University, Seoul, South Korea

    Jin-Kook Kim

  6. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, College of Medicine, Dankook University, Cheonan, South Korea

    Ji-Hun Mo

  7. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Korea University, Seoul, South Korea

    Jae-Min Shin

  8. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Pusan National University, Busan, South Korea

    Kyu-Sup Cho

  9. Department of Medical Statistics, School of Medicine, Catholic University of Daegu, Gyeongsan, South Korea

    Sang Gyu Kwak

  10. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu, Daegu, South Korea

    Seung-Heon Shin

  11. Department of Otorhinolaryngology, Daegu Catholic University Medical Center, 33 Duryugongwon-ro 17-gil, Nam-Gu, Daegu, 705-718, South Korea

    Seung-Heon Shin

Authors
  1. Dae Woo Kim
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  2. Yong Min Kim
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  3. Jin-Young Min
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  4. Jeong-Whun Kim
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  5. Jin-Kook Kim
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  6. Ji-Hun Mo
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  7. Jae-Min Shin
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  8. Kyu-Sup Cho
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  9. Sang Gyu Kwak
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  10. Seung-Heon Shin
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Contributions

Conceptualization: all authors. Data curation: all authors. Formal analysis: SGK. Methodology: all authors. Project administration: S-HS. Writing-original draft: DWK, YMK. Review and editing: DWK, YMK, and S-HS.

Corresponding author

Correspondence to Seung-Heon Shin.

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Kim, D.W., Kim, Y.M., Min, JY. et al. Clinicopathologic characteristics of paranasal sinus fungus ball: retrospective, multicenter study in Korea. Eur Arch Otorhinolaryngol 277, 761–765 (2020). https://doi.org/10.1007/s00405-019-05738-5

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  • DOI: https://doi.org/10.1007/s00405-019-05738-5

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