Summary
An orifice equation for the non-invasive measurement of mitral-valve area is demonstrated. It is shown that by combining this expression with the assumption of mitral-valve area invariance an orifice equation for the non-invasive assessment of cardiac output in conditions of mitral stenosis using simple echographically measureable variables can be developed. This equation is\(\dot V = (21)^{ - 1} R \cdot A \cdot T^2 \), where\(\dot V\) output in ml, R=heart frequency, A=mitral-valve area in cm2 and T=diastolic-filling period in sec·min−1. These results suggest that when mitral-valve area is accurately measured at one point in time, cardiac output may be measured at subsequent times at a clinically useful level from a knowledge of the echographically measurable variables of heart rate and diastolic-filling period.
Zusammenfassung
Eine Öffnungsgleichung für die nichtinvasive Messung des Mitralklappenareals wird dargestellt. Es wird gezeigt, daß durch Verbindung dieser Gleichung mit der Annahme eines konstanten Mitralklappenareals eine Öffnungsgleichung für die nichtinvasive Beurteilung des Herzminutenvolumens in Mitralstenose mittels echokardiographisch meßbarer Variablen entwickelt werden kann. Diese Gleichung lautet:\(\dot V = (21)^{ - 1} RAT^2 \), wobei\(\dot V\) in ml, R=Herzfrequenz, A=Mitralklappenareal in cm2, und T=diastolische Füllperiode in s/min. Die Resultate weisen darauf hin, daß, wenn das Mitralöffnungsareal zu einem bestimmten Zeitpunkt genau gemessen wurde, das Herzminutenvolumen in der Folgezeit beliebig oft und mit klinisch signifikanter Wertigkeit mittels der echographisch meßbaren Variablen von Herzfrequenz und diastolischer Füllperiode gemessen werden kann.
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Seitz, W.S., Spiel, M.S., Operschall, J. et al. Echographic method for the estimation of cardiac output from mitral-valve area, heart rate, and diastolic-filling period in conditions of mitral stenosis: correlation with cardiac catheterization. Basic Res Cardiol 78, 28–38 (1983). https://doi.org/10.1007/BF01923191
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DOI: https://doi.org/10.1007/BF01923191