Abstract
When analysed by an immuno-fluorescent test method allSaccharomyces spp. examined were antigenically distinguishable, with no natural grouping of yeast strains. The sero-types exhibited a continuous spectrum of antigen combinations. Extensive cellular variation was detected in serological response, which principally resulted from physiological differences between individual yeast cells but mutation was a minor contributor. Combination of divisiveness of the current serological analysis and the presence of transient physiologically-based “antigenic variants” rendered serology of dubious significance for yeast taxonomy. The role of yeast serology is assured, however, in relation to rapid test procedures for yeast identification.
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The author wishes to thank the Directors of Bass Production Ltd., for permission to publish this Paper.
Generous donations of rabbit antisera from Dr. I. Campbell, Heriot-Watt University, are gratefully acknowledged.
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Richards, M. Serology and yeast classification. Antonie van Leeuwenhoek 38, 177–192 (1972). https://doi.org/10.1007/BF02328090
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DOI: https://doi.org/10.1007/BF02328090