Summary
Five-choice visual discrimination learning was determined in four different strains of inbred mice. All strains were able to learn this task in a small number of sessions. By distributing or massing the practice further evidence was obtained suggesting that efficient consolidation mechanisms characterize the strain DBA/2J while short-term memory characterizes C3H/He mice.
Nicotine exerted a facilitating effect in three out of four strains. The magnitude of the effect seemed to be related to the basal abilities of each strain or to the complexity of the task.
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References
Bovet-Nitti, F.: Facilitation of simultaneous visual discrimination in the rat. Psychopharmacologia (Berl.) 10, 59–66 (1966).
Bovet, D., F. Bovet-Nitti, and A. Oliverio: Action of nicotine on spontaneous and acquired behavior in rats and mice. Ann. N. Y. Acad. Sci. 142, 261–267 (1967).
— — —: Memory and consolidation mechanisms in avoidance learning of inbred mice. Brain Res. 10, 168–182 (1968).
Fox, M. W.: The visual cliff test for the study of visual depth perception in the mouse. Anim. Behav. 13, 232–233 (1965).
King, J. A., and R. G. Weisman: Visual discrimination in deermice. Psychonom. Sci. 4, 42–44 (1966).
Krevank, J., and J. L. McGaugh: Effects of pentylenetetrazol on memory storage in mice. Psychopharmacologia (Berl.) 12, 303–321 (1968).
Lindzey, J. G., and H. Winston: Maze-learning and effects of pretraining in inbred strains of mice. J. comp. physiol. Psychol. 55, 748–751 (1962).
McClearn, G. E.: Performance differences among mouse strains in a learning situation. Amer. Psychol. 13, 405 (abstr.) (1958).
—, and W. Meredith: Behavioral genetics. Ann. Rev. Psychol. 17, 515–550 (1966).
Mithlesh, G., and H. C. Holland: Consolidation and maze-learning: a further study of post-trial injections of a stimulant drug (nicotine). Int. J. Neuropharmacol. 7, 55–59 (1968).
Morrison, C. F.: Effects of nicotine on operant behaviour of rats. Int. J. Neuropharmacol. 6, 229–240 (1967).
Oliverio, A., J. L. McGaugh, and D. Bovet: Strain differences in passive avoidance learning and in the amnestic effects of electroconvulsive schock. Communications in Behavioral Biology (in press).
Rowley, J. B., and M. M. Bolles: Form discrimination in white mice. J. comp. physiol. Psychol. 20, 205–210 (1935).
Sidman, R. L., and M. C. Green: Retinal degeneration in the mouse: location of the rd locus in linkage group XVII. J. Hered. 56, 23–29 (1965).
Wimer, R.: (unpublished data). In: Biology of the laboratory mouse, E. L. Green ed., p. 709. New York: McGraw-Hill 1966.
—, and S. Weller: Evaluation of a visual discrimination task for the analysis of the genetics of a mouse behavior. Percep. Mot. Skills 20, 203–208 (1965).
Yerkes, R. M.: The dancing mouse, p. 290. New York: Mac Millan 1907.
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Bovet-Nitti, F. Facilitation of simultaneous visual discrimination by nicotine in four “inbred” strains of mice. Psychopharmacologia 14, 193–199 (1969). https://doi.org/10.1007/BF00404217
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DOI: https://doi.org/10.1007/BF00404217