Skip to main content
SpringerLink
Log in

On the problem of regional gene duplication in diploid fish of the orders Ostariophysi and Isospondyli

  • Original Investigations
  • Published:
Humangenetik Aims and scope Submit manuscript

Summary

DNA measurements, the number of chromosomes and the analysis of individual gene loci revealed a diploid-tetraploid relationship among members of the fish family Cyprinidae. Intermediate DNA values in some diploid species of this family are interpreted as the result of regional duplications. However, the analysis of 8 different isoenzyme systems in these species always confirmed the presence of only the dioploid number of genes; this includes the gene for the enzyme 6-PGD which was erraneously reported to be duplicated.

In the order Isospondyli, on the other hand, where a diploid-tetraploid relationship has likewise been established, the smelt, Osmerus esperlanus provides a clear example for the duplication of single genes. In this representative of the diploid group the genes for S-AAT and PGI are duplicated.

Zusammenfassung

DNS-Messungen, Chromosomenanalysen und die Untersuchung individueller Genloci haben eine Diploid-tetraploid-Beziehung in der Fischfamilie Cyprinidae aufgedeckt. Intermediäre DNS-Werte bei einigen diploiden Species dieser Fischfamilie werden als Folge regionaler Duplikationen interpretiert. Die Analyse von 8 verschiedenen Isoenzymsystemen ergab jedoch für diese Species jeweils nur die diploide Anzahl von Genen; das schließt auch den 6-PGD-Locus mit ein, der irrtümlicherweise als dupliziert angesehen worden war. In der Ordnung Isospondyli, in der ebenfalls eine Diploid-tetraploid-Beziehung etabliert ist, gibt jedoch der Stint, Osmerus esperlanus, ein klares Beispiel für die Duplikation einzelner Genloci. Bei diesem Repräsentanden der diploiden Gruppe sind die für die S-AAT und die PGI codierenden Gene dupliziert.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bender, K., Ohno, S.: Duplication of the autosomally inherited 6-phosphoglyconate dehydrogenase gene locus in tetraploid species of cyprinid fish. Biochem. Genet. 2, 101–107 (1968)

    Article  CAS  Google Scholar 

  • Comings, D. E., Berger, R. O.: Gene products of Amphiuma: an amphibien with an excessive amount of DNA. Biochem. Genet. 2, 319–333 (1969)

    Article  CAS  Google Scholar 

  • Darnall, D. W., Klotz, I. M.: Protein subunits: A table (revised edition). Arch. Biochem. Biophys. 149, 1–14 (1972)

    Article  CAS  Google Scholar 

  • Engel, W., Faust, J., Wolf, U.: Isoenzyme polymorphism of the sorbitol dehydrogenase and the NADP-dependent isocitrate dehydrogenase in the fish family Cyprinidae. Anim.Blood Grps. biochem. Genet. 2, 127–133 (1971)

    Article  CAS  Google Scholar 

  • Engel, W., Schmidtke, J., Vogel, W., Wolf, U.: Genetic polymorphism of lactate dehydrogenase isoenzymes in the carp (Cyprinus carpio) apparently due to a “null allele”. Biochem. Genet. 8, 281–289 (1973)

    Article  CAS  Google Scholar 

  • Kadir, S.: Untersuchungen zur Gewebsvariabilität der Isoenzyme, dargestellt am Beispiel der 6-Phosphogluconat-Dehydrogenase vom Goldfisch (Carassius auratus). Dissertation, Freiburg i. Br. 1969

  • Kazazian, H. H.: Molecular size studies on 6-phosphogluconate dehydrogenase. Nature (Lond.) 212, 197–198 (1966)

    Article  CAS  Google Scholar 

  • Klose, J., Wolf, U., Hitzeroth, H., Ritter, H., Atkin, N. B., Ohno, S.: Duplication of the LDH gene loci by polyploidisation in the fish order Clupeiformes. Humangenetik 5, 190–196 (1968)

    CAS  PubMed  Google Scholar 

  • Klose, J., Wolf, U., Hitzeroth, H., Ritter, H., Ohno, S.: Polyploidisation in the fish family Cyprinidae, order Cypriniformes, II. Duplication of the gene loci coding for lactate dehydrogenase (E.C.: 1.1.1.27) and 6-phosphogluconate dehydrogenase (E.C.: 1.1.1.44) in various species of Cyprinidae. Humangenetik 7, 245–250 (1969)

    CAS  PubMed  Google Scholar 

  • Lin, C.-C., Schipman, G., Kittrell, W. A., Ohno, S.: The predominance of heterozygotes found in wild goldfish of lake Erie at the gene locus for sorbitol dehydrogenase. Biochem. Genet. 3, 603–607 (1969)

    Article  CAS  Google Scholar 

  • Ohno, S.: Evolution by gene duplication. Berlin-Heidelberg-New York: Springer 1970

    Book  Google Scholar 

  • Schmidtke, J., Engel, W.: Duplication of the gene loci coding for the supernatant aspartate aminotransferase by polyploidisation in the fish family Cyprinidae. Experientia (Basel) 28, 976–978 (1972)

    Article  CAS  Google Scholar 

  • Wolf, U., Ritter, H., Atkin, N. B., Ohno, S.: Polyploidisation in the fish family Cyprinidae, order Cypriniformes. I. DNA-content and chromosome sets in various species of Cyprinidae. Humangenetik 7, 240–244 (1969)

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Humangenetik und Anthropologie der Universität Freiburg i.Br., Freiburg i.Br., Germany

    Jörg Schmidtke & Wolfgang Engel

Authors
  1. Jörg Schmidtke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wolfgang Engel
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by the Deutsche Forschungsgemeinschaft

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schmidtke, J., Engel, W. On the problem of regional gene duplication in diploid fish of the orders Ostariophysi and Isospondyli . Hum Genet 21, 39–45 (1974). https://doi.org/10.1007/BF00278563

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00278563

Keywords

Search

Navigation