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Classification of Meningioma Using Immunogenic Antigens

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Tumors of the Central Nervous System, Volume 11

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 11))

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Abstract

Diagnosis of meningioma is often an incidental finding. Although the majority of meningioma is clinically benign, a relevant subgroup of them is prone to recur and inherit a poor prognosis. Biological markers for this subgroup or for the early detection of meningioma are not known or not generally accepted. A novel method might improve early detection of meningioma. Autoantibodies generated from the patients’ immune system directed against proteins expressed from the meningioma tumours might aid in early detection of meningioma. Because the autoantibody repertoire reflects the expression of the tumour, autoantibodies also might hold the potential to differentiate between the benign meningiomas and the meningiomas with worse prognosis.

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Authors and Affiliations

  1. Department of Human Genetics, Medical Faculty, Saarland University, Building 60, Kirrberger Strasse, D-66421, Homburg, Saar, Germany

    Nicole Ludwig

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  1. Nicole Ludwig
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Correspondence to Nicole Ludwig .

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  1. Kean University, Room 213, Library building, Union, New Jersey, USA

    M.A. Hayat

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Ludwig, N. (2014). Classification of Meningioma Using Immunogenic Antigens. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 11. Tumors of the Central Nervous System, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7037-9_24

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  • DOI: https://doi.org/10.1007/978-94-007-7037-9_24

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-7036-2

  • Online ISBN: 978-94-007-7037-9

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