Abstract
More than half a million Americans annually suffer a sudden cardiac arrest. Initial resuscitation of the pulseless patient should follow American Heart Association guidelines. Patients with return of spontaneous circulation are at significant risk for rearrest or poor outcome without early and advanced critical care interventions. Early post-arrest management should focus on three parallel goals: diagnosis and treatment of the underlying cause of cardiac arrest, evaluation of the severity of post-arrest illness, and supportive care of the postcardiac arrest syndrome. Patients who remain comatose after cardiac arrest should be cared for at hospital capable of providing advanced cardiac and critical care interventions.
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Abbreviations
- CNS:
-
Central nervous system
- PaCO2:
-
Partial pressure of carbon dioxide
- COPD:
-
Chronic obstructive pulmonary disease
- CT:
-
Computed tomography
- CXR:
-
Chest X-ray
- DKA:
-
Diabetic ketoacidosis
- ECG:
-
Electrocardiogram
- ED:
-
Emergency department
- EEG:
-
Electroencephalogram
- EMS:
-
Emergency medical services
- FOUR:
-
Full outline of unresponsiveness
- GI:
-
Gastrointestinal
- ICU:
-
Intensive care unit
- MAP:
-
Mean arterial pressure
- MRI:
-
Magnetic resonance imaging
- OHCA:
-
Out-of-hospital cardiac arrest
- PaO2:
-
Partial pressure of oxygen
- ROSC:
-
Return of spontaneous circulation
- RV:
-
Right ventricle
- SAH:
-
Subarachnoid hemorrhage
- TTM:
-
Targeted temperature management
- UA:
-
Urinalysis
References
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation. 2015;131(4):e29–322. Epub 2014/12/19.
Stub D, Bernard S, Duffy SJ, Kaye DM. Post cardiac arrest syndrome: a review of therapeutic strategies. Circulation. 2011;123(13):1428–35. Epub 2011/04/06
Field JM, Hazinski MF, Sayre MR, Chameides L, Schexnayder SM, Hemphill R, et al. Part 1: executive summary 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2010;122(18 suppl 3):S640–S56.
Wang C-H, Chou N-K, Becker LB, Lin J-W, Yu H-Y, Chi N-H, et al. Improved outcome of extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest–a comparison with that for extracorporeal rescue for in-hospital cardiac arrest. Resuscitation. 2014;85(9):1219–24.
Coppler PJ, Elmer J, Calderon L, Sabedra A, Doshi AA, Callaway CW, et al. Validation of the Pittsburgh Cardiac Arrest Category illness severity score. Resuscitation. 2015;89:86–92.
Rittenberger JC, Doshi AA, Reynolds JC, Service PCA. Postcardiac arrest management. Emerg Med Clin North Am. 2015;33:691.
Cocchi MN, Lucas JM, Salciccioli J, Carney E, Herman S, Zimetbaum P, et al. The role of cranial computed tomography in the immediate post-cardiac arrest period. Intern Emerg Med. 2010;5(6):533–8.
Metter RB, Rittenberger JC, Guyette FX, Callaway CW. Association between a quantitative CT scan measure of brain edema and outcome after cardiac arrest. Resuscitation. 2011;82(9):1180–5.
Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002;346(8):557–63.
Nikolov NM, Cunningham AJ. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. Survey Anesthesiol. 2003;47(4):219–20.
Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, et al. Targeted temperature management at 33 C versus 36 C after cardiac arrest. N Engl J Med. 2013;369(23):2197–206.
Camuglia AC, Randhawa VK, Lavi S, Walters DL. Cardiac catheterization is associated with superior outcomes for survivors of out of hospital cardiac arrest: review and meta-analysis. Resuscitation. 2014;85(11):1533–40.
Reynolds JC, Rittenberger JC, Toma C, Callaway CW, Service TPCA. Risk-adjusted outcome prediction with initial post-cardiac arrest illness severity: implications for cardiac arrest survivors being considered for early invasive strategy. Resuscitation. 2014;85(9):1232–9.
Redfors B, Råmunddal T, Angerås O, Dworeck C, Haraldsson I, Ioanes D, et al. Angiographic findings and survival in patients undergoing coronary angiography due to sudden cardiac arrest in Western Sweden. Resuscitation. 2015;90:13–20.
Beylin ME, Perman SM, Abella BS, Leary M, Shofer FS, Grossestreuer AV, et al. Higher mean arterial pressure with or without vasoactive agents is associated with increased survival and better neurological outcomes in comatose survivors of cardiac arrest. Intensive Care Med. 2013;39(11):1981–8.
Elmer J, Scutella M, Pullalarevu R, Wang B, Vaghasia N, Trzeciak S, et al. The association between hyperoxia and patient outcomes after cardiac arrest: analysis of a high-resolution database. Intensive Care Med. 2015;41(1):49–57.
Vaahersalo J, Bendel S, Reinikainen M, Kurola J, Tiainen M, Raj R, et al. Arterial blood gas tensions after resuscitation from out-of-hospital cardiac arrest: associations with long-term neurologic outcome∗. Crit Care Med. 2014;42(6):1463–70.
Sandroni C, Cavallaro F, Callaway CW, D’Arrigo S, Sanna T, Kuiper MA, et al. Predictors of poor neurological outcome in adult comatose survivors of cardiac arrest: a systematic review and meta-analysis. Part 2: patients treated with therapeutic hypothermia. Resuscitation. 2013;84(10):1324–38.
Gold B, Puertas L, Davis SP, Metzger A, Yannopoulos D, Oakes DA, et al. Awakening after cardiac arrest and post resuscitation hypothermia: are we pulling the plug too early? Resuscitation. 2014;85(2):211–4.
Institute of Medicine. Strategies to Improve Cardiac Arrest Survival: A Time to Act. 2015; Available from: http://iom.nationalacademies.org/~/media/Files/Report%20Files/CardiacArrestReportBrief.pdf.
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Becker, T.K., Elmer, J. (2020). Cardiac Arrest and the Post-arrest Syndrome. In: Shiber, J., Weingart, S. (eds) Emergency Department Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-030-28794-8_11
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