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Antiphospholipid syndrome and palindromic rheumatism: a new possible association

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Abstract

Objective

The aim of this study was to report six patients with palindromic rheumatism (PR) in whom signs, symptoms, and/or serologic evidence of antiphospholipid syndrome (APS) developed.

Methods

The medical histories of the patients were reviewed with special emphasis on age, gender, duration of PR, and lapse of time until antiphospholipid antibodies were detected or APS was diagnosed. Three representative cases are described.

Results

Two patients were women and four were men. Their mean age was 49.3 years (range 36–80), and the mean duration of PR was 5.5 years (range 3–8). In all patients, raised titers of antiphospholipid antibodies were found on two or more occasions. Two patients developed clinical pictures compatible with APS, two showed symptoms which may be attributable for APS, and raised titers of antiphospholipid antibodies were found in only two.

Conclusion

It seems that the appearance of these two uncommon conditions together is more than coincidental and may point to a previously unreported clinical association.

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Authors and Affiliations

  1. Rheumatology Outpatient Clinics, Barzilai Medical Centre, 3 Histadrut St., Ashkelon 78306, Israel

    Tatiana Reitblat

  2. Sourasky Medical Centre, Department of Rheumatology, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    Irena Litinsky, Dan Caspi & Ori Elkayam

Authors
  1. Tatiana Reitblat
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  2. Irena Litinsky
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  3. Dan Caspi
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  4. Ori Elkayam
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Correspondence to Tatiana Reitblat.

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Reitblat, T., Litinsky, I., Caspi, D. et al. Antiphospholipid syndrome and palindromic rheumatism: a new possible association. Rheumatol Int 25, 595–598 (2005). https://doi.org/10.1007/s00296-004-0489-2

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  • DOI: https://doi.org/10.1007/s00296-004-0489-2

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