Abstract
Objective
To describe the characteristic US and MR findings of subcutaneous epidermal inclusion cysts.
Materials and methods
Seventy-nine patients with subcutaneous epidermal inclusion cysts underwent US (n = 70), MR (n = 7), or both (n = 2). On US, the margin, shape, echogenicity, through-transmission, wall, internal debris and vascularity were evaluated. On MR, the shape, wall, signal intensity, internal debris, and enhancement pattern were evaluated.
Results
On US, characteristic findings were well circumscribed (n = 69, 96%), ovoid-shaped (n = 56, 78%), heterogeneously and mildly echogenic (n = 66, 92%), increased through-transmission (n = 66, 92%) and low echoic rim (n = 48, 67%). Internal debris was seen in 31 cases (43%) and often contained linear echogenic reflections (n = 12, 17%), dark clefts (n = 13, 18%), or a mixture (n = 5, 7%). Most masses showed no Doppler flow (n = 70, 97%). On MR, all cases demonstrated a well-demarcated oval-shaped mass with a surrounding rim. On T1-weighted image (WI), the mass showed slightly high T1 signal in 4/9 (44%) and iso-signal in 5/9 (56%). On T2WI, the mass showed high signal in 6/9 (67%), intermediate in 2/9 (22%), and a target appearance in 1/9 (11%). Internal linear dark T2 signal debris was observed in 4/9 (44%). All lesions showed peripheral rim enhancement without central enhancement.
Conclusions
On US, subcutaneous epidermal inclusion cysts are usually well-circumscribed, oval-shaped, mildly echogenic masses with occasional linear anechoic and/or echogenic reflections, increased through-transmission, hypoechoic rim and no Doppler flow. On MR, an intermediate to high T2 signal mass with occasional low signal debris and no central enhancement can strengthen the diagnosis.
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References
Lever WF, Lever GS. Tumor and cysts of epidermis. In: Elder D, editor. Histopathology of the skin. 8th ed. Philadelphia, JB: Lippincott, 1997, p. 685-746
Elder D, Elenitsas R, Jaworsky C, Johnson Jr B. Lever’s histopathology of the skin. 8th ed. Philadelphia: Lippincott-Raven; 1997. p. 695–721.
Denison CM, Ward VL, Lester SC, DiPiro PJ, Smith DN, Meyer JE, et al. Epidermal inclusion cysts of the breast: Three lesions with calcifications. Radiology. 1997;204(2):493–6.
Yasumoto M, Shibuya H, Gomi N, Kasuga T. Ultrasonographic appearance of dermoid and epidermoid cysts in the head and neck. J Clin Ultrasound. 1991;19(8):455–61.
Dogra V. Testicular epidermoid cysts. Am J Roentgenol. 2002;179(4):1075–5.
Jackson VP, Edmond VJ. Breast ultrasonography. In: LW JVP, Fu KL, Fu YS, editors. Diagnosis of disease of the breast. 2nd ed. Philadelphia: Elsevier Saunders; 2005. p. 175–92.
Yang DM, Yoon MH, Kim HS, Oh YH, Ha SY, Oh JH, et al. Presacral epidermoid cyst: imaging findings with histopathologic correlation. Abdom Imaging. 2001;26(1):79–82.
Eisenmenger M, Lang S, Donner G, Kratzik C, Marberger M. Epidermoid cysts of the testis: organ-preserving surgery following diagnosis by ultrasonography. Br J Urol. 1993;72(6):955–7.
Langer JE, Ramchandani P, Siegelman ES, Banner MP. Epidermoid cysts of the testicle: Sonographic and MR imaging features. Am J Roentgenol. 1999;173(5):1295–9.
Shibata T, Hatori M, Satoh T, Ehara S, Kokubun S. Magnetic resonance imaging features of epidermoid cyst in the extremities. Arch Orthop Traum Su. 2003;123(5):239–41.
Hong SH, Chung HW, Choi JY, Koh YH, Choi JA, Kang HS. MRI findings of subcutaneous epidermal cysts: emphasis on the presence of rupture. AJR Am J Roentgenol. 2006;186(4):961–6.
Brenner JS, Cumming WA, Ros PR. Testicular epidermoid cyst—sonographic and MR findings. Am J Roentgenol. 1989;152(6):1344–4.
Cho JH, Chang JC, Park BH, Lee JG, Son CH. Sonographic and MR imaging findings of testicular epidermoid cysts. Am J Roentgenol. 2002;178(3):743–8.
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Kim, H.K., Kim, S.M., Lee, S.H. et al. Subcutaneous epidermal inclusion cysts: Ultrasound (US) and MR imaging findings. Skeletal Radiol 40, 1415–1419 (2011). https://doi.org/10.1007/s00256-010-1072-4
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DOI: https://doi.org/10.1007/s00256-010-1072-4