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Preoperative liquid embolization of cerebeller hemangioblastomas using N-butyl cyanoacrylate

  • Interventional Neuroradiology
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Abstract

Introduction

We aim to present and discuss clinical outcomes of preoperative liquid embolization of hemangioblastomas (HB) using N-butyl cyanoacrylate (NBCA).

Methods

From 1999 through 2010, 19 patients presenting with symptoms of vertigo and/or headaches were diagnosed with HB based on preoperative magnetic resonance imaging and cerebral angiographic findings at our institution. Preoperative embolization with NBCA was performed on tumors in 10 of 21 operations for 19 patients. For each of these patients, the lesion was pathologically confirmed as HB.

Results

Embolization had a favorable outcome in all patients. No permanent neurological complications were observed after preoperative embolization using NBCA. However, thalamic infarction and minor hemorrhage were observed in two patients with cerebellar HB.

Conclusion

The authors recommend NBCA as an embolization material for large cerebellar HB.

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Abbreviations

CI:

Cerebral infarction

CT:

Computed tomography

D:

Dead

DSA:

Cerebral digital subtraction angiography

EVD:

External ventricular drainage

F:

Female

GR:

Good recovery

HB:

Hemangioblastomas

HMA:

Hydroxyethylmethacrylate-co-methyl methacrylate

M:

Male

MRI:

Magnetic resonance imaging

PAO:

Parent artery occlusion

PVA:

Polyvinyl alchol

PVS:

Persistent vegetative state

NBCA:

N-Butyl cyanoacrylate

VHL:

von Hippel–Lindau disease

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Conflict of interest

We declare that we have no conflict of interest.

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Authors and Affiliations

  1. Department of Neurosurgery, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo, 113-86, Japan

    Yasuo Murai, Shushi Kominami, Yoichi Yoshida, Takayuki Mizunari, Koji Adachi, Kenta Koketsu, Shiro Kobayashi & Akira Teramoto

  2. Department of Neurosurgery, Chiba Hokusou Hospital, Chiba, Japan

    Yasuo Murai, Shushi Kominami, Yoichi Yoshida, Takayuki Mizunari, Koji Adachi, Kenta Koketsu, Shiro Kobayashi & Akira Teramoto

Authors
  1. Yasuo Murai
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  2. Shushi Kominami
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  3. Yoichi Yoshida
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  4. Takayuki Mizunari
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  5. Koji Adachi
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  6. Kenta Koketsu
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  7. Shiro Kobayashi
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  8. Akira Teramoto
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Corresponding author

Correspondence to Yasuo Murai.

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Murai, Y., Kominami, S., Yoshida, Y. et al. Preoperative liquid embolization of cerebeller hemangioblastomas using N-butyl cyanoacrylate. Neuroradiology 54, 981–988 (2012). https://doi.org/10.1007/s00234-011-0985-5

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  • DOI: https://doi.org/10.1007/s00234-011-0985-5

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