Summary
This report describes a medulloblastoma with extracranial metastases in a 24-year-old man. Postoperatively, 60Co irradiation was given and clinical recovery was good. Cervical lymph node metastases developed 2.5 years later. The patient received cytostatic treatment and a second course of radiation therapy with 60Co and lived for 6 years after the onset of symptoms, finally dying with signs of bronchopneumonia. The possible routes of spread are discussed.
Zusammenfassung
Fallbericht eines 24jährigen Mannes mit Medulloblastom, kompliziert durch extrakranielle Metastasierung. Nach der Operation wurde die hintere Schädelpartie mit 60Co bestrahlt. Zweieinhalb Jahre später traten histologisch verifizierte zervikale Lymphknotenmetastasen auf. Er wurde zytostatisch behandelt und erneut bestrahlt (60Co) und starb 6 Jahre nach Beginn der Symptome an Bronchopneumonie. Mögliche Wege der Metastasierung dieses neuroektodermalen Tumors werden diskutiert.
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Morild, I., Mørk, S. & Nyland, H. Metastasizing neuroectodermal tumour. J Neurol 227, 151–155 (1982). https://doi.org/10.1007/BF00313569
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DOI: https://doi.org/10.1007/BF00313569