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Observations on the Anticatabolic Effect of Xylitol in the Posttraumatic Phase

  • Conference paper
International Symposium on Metabolism, Physiology, and Clinical Use of Pentoses and Pentitols

Abstract

At the beginning of the century, Abderhalden sen. was of the opinion that an intravenous nutrition might be developed with the basic elements of different substances. Since, during the last 20 years, this prediction has been fulfilled — as far as the metabolism of proteins is concerned — by amino acid solutions of a relatively ideal composition [3, 17–19], we were confronted with the task of finding new ways allowing the parenteral administration of immediately utilizable metabolites of the energy metabolism in sufficient quantities. In practice we have to choose between glucose, fructose, sorbitol and xylitol. There are frequently hyperglycemia and glucosuria in the posttraumatic phase indicating a disturbed utilization of glucose. By means of an intravenous administration of glucose according to Conard [5] we were able to find a disturbed glucose assimilation in more than 20 patients after laparotomy or bone fractures by calculating the elimination constant K G . The value of glucose infusions during catabolism caused by stress is doubtful. The administration of fructose, sorbitol and xylitol seems to be more advantageous.

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References

  1. Bässler, K. H., W. Prellwitz, V. XJnbehaun, K. Lang: XylitstoffWechsel beim Menschen. Zur Frage der Eignung von Xylit als Zucker-Ersatz beim Diabetiker. Klin. Wschr. 40, 791–793 (1962).

    Google Scholar 

  2. Bässler, K. H., V. Unbehaun, W. Prellwitz: Enzymatische Bestimmungen von Xylit in biologischem Material. Biochem. Z. 336, 35–40 (1962).

    Google Scholar 

  3. Bauer, B. L., K. Schultis: Posttraumatische Katabolie und parenterale Ernährung. Der Eiweißstoffwechsel. Actuelle Chir. 1, 281–286 (1967).

    Google Scholar 

  4. Bergmeyer, H. U.,. E. Bernt: Enzymatische Bestimmung von Keton-Körpern im Blut. Enzym, biol. clin. 5, 65–76 (1965).

    CAS  Google Scholar 

  5. Conard, Y.: Mesure de 1Jassimilation du glucose. Bases theoriques et applications cliniques. Les Editions Acta Medica Belgica, Bruxelles 1955.

    Google Scholar 

  6. Geser, C. A., H. Förster, H. Pröls, H. Mehnert: Zur Frage einer Wirkung von Xylit auf die Insulinsekretion des Menschen. Klin. Wschr. 45, 851–852 (1967).

    Article  PubMed  CAS  Google Scholar 

  7. Hales, C. N., P. J. Rändle: Immunoassay of insulin with insulin-antibody precipitate. Biochem. J. 88, 137 (1963).

    PubMed  CAS  Google Scholar 

  8. Hirata, Y., M. Fujisawa, H.Sato, T. Asano, S. Katsuki: Blood glucose and plasma insulin responses to xylitol administrated intravenously in dog. Biochem. biophys. Res. Commun. 24, 471–475 (1966).

    CAS  Google Scholar 

  9. Kuzuya, T., Y. Kanazawa, K. Kosaka: Plasma insulin response to intravenously administered xylitol in dogs. Metabolism 15, 1149–1152 (1966).

    Article  PubMed  CAS  Google Scholar 

  10. Lang, K.: Xylit als Nahrungskohlenhydrat. Med. u. Ernähr. 4, 45–50 (1963).

    Google Scholar 

  11. Mehnert, H., J. D. Summa, H. Förster: Untersuchungen zum Xylit-stoffWechsel bei gesunden, leberkranken und diabetischen Personen. Klin. Wschr. 42, 382–387 (1964).

    Article  PubMed  CAS  Google Scholar 

  12. Mosinger, F.: Photometrie adaptation of Dole’s microdetermination of free fatty acids. J. Lipid Res. 6, 157–159 (1965).

    PubMed  CAS  Google Scholar 

  13. Randle, P. J.: The glucose fatty acid cycle, its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963, 785–789.

    Google Scholar 

  14. Rodewald, G., H. Harms: Beziehungen zwischen Po2 und Pco2 in Normo- und Hypothermie. Anaesthesist 13, 113–117 (1964).

    PubMed  CAS  Google Scholar 

  15. Schmidt, F. H.: Die enzymatische Bestimmung von Glucose und Fructose nebeneinander. Klin. Wschr. 39, 1244–1247 (1961).

    Article  PubMed  CAS  Google Scholar 

  16. Schultis, K.: Utilisation i. v. zugeführter Aminosäuren unter Insulin. Symposion Int. Soc. of Parenteral Nutrition Hamburg 5./6. 8. 1966. Lochham b. München: Pallas Verlag 1967.

    Google Scholar 

  17. Schultis, K.: Erfahrungen bei der parenteralen Ernährung chirurgischer Patienten. In: Parenterale Ernährung, hrsg. von K. Lang, R. Frey u. M. Hal-mágyi in Anaesthesiologie und Wiederbelebung, Bd. 6, S. 80–86, hrsg. von R. Frey, F. Kern u. O. Mayerhofer. Berlin-Heidelberg-New York: Springer 1966.

    Google Scholar 

  18. Schultis, K., B.L.Bauer: Grundlagen und praktische Anwendung der parenteralen Ernährung in der postoperativen Phase. Z. prakt. Anästh. Wiederbeleb. 2, 228–239 (1967).

    Google Scholar 

  19. Schultis, K., H. L’Allemand: Zur Ernährung Tetanuskranker. Anaesthesist 17, 196–201 (1968).

    PubMed  CAS  Google Scholar 

  20. Toussaint, W., K. Roggenkamp, K. H. Bässler: Behandlung der Ketonämie im Kindesalter mit Xylit. Z. Kinderheilk. 98, 146–154 (1967).

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Chirurgische Klinik, Giessen University, Giessen, West Germany

    K. Schultis & C. A. Geser

  2. Medizinische Poliklinik, Munich University, München, West Germany

    K. Schultis & C. A. Geser

Authors
  1. K. Schultis
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  2. C. A. Geser
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Editor information

Editors and Affiliations

  1. Department of Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA

    Bernard L. Horecker

  2. Physiologisch-Chemisches Institut, Johannes Gutenberg-Universität, Mainz, West Germany

    Konrad Lang

  3. Department of Biochemistry, Kyushu University School of Medicine, Fukuoka, Japan

    Yasuyuki Takagi

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© 1969 Springer-Verlag, Berlin Heidelberg

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Schultis, K., Geser, C.A. (1969). Observations on the Anticatabolic Effect of Xylitol in the Posttraumatic Phase. In: Horecker, B.L., Lang, K., Takagi, Y. (eds) International Symposium on Metabolism, Physiology, and Clinical Use of Pentoses and Pentitols. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46191-0_39

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  • DOI: https://doi.org/10.1007/978-3-642-46191-0_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-46193-4

  • Online ISBN: 978-3-642-46191-0

  • eBook Packages: Springer Book Archive

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