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Nephron-Sparing Surgery for Renal Cancer

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Renal Cell Carcinoma

Part of the book series: Current Clinical Urology ((CCU))

Abstract

The significant increase in the use of cross-sectional imaging over the past decades has coincided with a dramatic increase in the incidence of small renal tumors. The biological potential of these tumors tends to be more favorable than larger tumors. The surgical treatment paradigm for small localized renal tumors has shifted from radical nephrectomy to nephron-sparing surgery (NSS) with the goal of preserving long-term renal function without affecting cancer control. Partial nephrectomy, initially reserved for patients with bilateral tumors, tumor in a solitary kidney or patients with chronic kidney disease, has become the standard of care for tumors ≤4 cm in diameter where the contralateral kidney is normal. This chapter will cover the expanding indications for NSS, as well as the role of minimally invasive surgery. The functional and oncological outcomes will also be discussed.

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Authors and Affiliations

  1. Division of Urologic Oncology, Department of Urology, University of Michigan, 3875 Taubman Center SPC 5330, 1500 East Medical Center Drive, Ann Arbor, MI, 48109, USA

    Alon Z. Weizer MD, MS, Jeffery S. Montgomery MD, MHSA & Khaled S. Hafez MD

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  1. Alon Z. Weizer MD, MS
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  2. Jeffery S. Montgomery MD, MHSA
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  3. Khaled S. Hafez MD
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Correspondence to Khaled S. Hafez MD .

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Editors and Affiliations

  1. Glickman Urological and Kidney Institute, Center for Urologic Oncology, Cleveland Clinic, Cleveland, 44195, Ohio, USA

    Steven C. Campbell

  2. College of Medicine, Case Western Reserve University, Cleveland Clinic Lerner, Department of Solid Tumor Oncology, Cleveland, 44195, Ohio, USA

    Brian I. Rini

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Weizer, A.Z., Montgomery, J.S., Hafez, K.S. (2013). Nephron-Sparing Surgery for Renal Cancer. In: Campbell, S., Rini, B. (eds) Renal Cell Carcinoma. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-062-5_8

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