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Lifestyle, Exercise and Osteoporosis

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HRT and Osteoporosis

Abstract

Involutional osteoporosis is incorrectly perceived as a “disease”. One clear fact emerges on review of the vast literature on the subject. Bone mass is inversely proportional to osteoporotic-related fractures; the greater the bone mass of individuals, irrespective of age, the less the chance of fracture [1]. Central to the physiological accrual of bone mass are two interrelated processes. The activity of the bone remodelling cycle, and lifestyle factors. These in turn are influenced by the individual’s chronological and reproductive age. For example, for a given loading strain the net rate of bone volume change is greater in “growing” than in “mature” bone [2]. This process is influenced by the loss of the modulating effect of oestrogen on the bone remodelling cycle with resulting increased osteoclast activity, deeper resorption cavities and an accelerated rate of bone loss in oestrogen-deprived women [3].

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  1. M. Notelovitz
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Editors and Affiliations

  1. Clarendon Wing, Leeds General Infirmary, Leeds, LS1 3EX, UK

    James O. Drife MD, FRCS Ed, FRCOG (Professor of Obstetrics and Gynaecology) (Professor of Obstetrics and Gynaecology)

  2. King’s College Hospital, London, SE5 9RS, UK

    John W. W. Studd MD, BS, FRCOG (Consultant Obstetrician and Gynaecologist, Director) (Consultant Obstetrician and Gynaecologist, Director)

  3. The Menopause Clinic, Dulwich Hospital, East Dulwich Grove, London, SE22 8PT, UK

    John W. W. Studd MD, BS, FRCOG (Consultant Obstetrician and Gynaecologist, Director) (Consultant Obstetrician and Gynaecologist, Director)

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© 1990 Springer-Verlag London Limited

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Notelovitz, M. (1990). Lifestyle, Exercise and Osteoporosis. In: Drife, J.O., Studd, J.W.W. (eds) HRT and Osteoporosis. Springer, London. https://doi.org/10.1007/978-1-4471-1799-5_24

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  • DOI: https://doi.org/10.1007/978-1-4471-1799-5_24

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