Abstract
Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow obstruction that does not markedly change over months of observation and is pathologically usually the result of chronic bronchitis or emphysema (1–3). It is estimated that 14–15 million people in the USA have COPD, with approximately 12.5 million having chronic bronchitis and 1.65–2 million emphysema (2). Asthma is highly prevalent, affecting an estimated 11 million people (4). There is evidence that the prevalence of asthma and COPD are increasing (5). Vollmer and colleagues noted an increased, prevalence of asthma and chronic airflow obstruction (CAO) over the period 1967–1987 in all age groups except males aged 65 and older who were enrolled in a large health maintenance organization (6). Every 5 years between 1950 and 1970 the death rate for obstructive respiratory disease doubled in the USA (7,8). COPD is the fourth leading cause of death in the USA, with 85 544 patients dying from COPD in 1991(2).
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Kazerooni, E.A., Flaherty, K.R., Martinez, F.J. (2001). Chronic Obstructive Pulmonary Disease. In: Sperber, M. (eds) Radiologic Diagnosis of Chest Disease. Springer, London. https://doi.org/10.1007/978-1-4471-0693-7_16
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