Abstract
Cancer staging allows patients to be stratified based on aggressiveness of their disease and provides important prognostic information to both the patient and clinician. The tumor-nodal-metastasis (TNM) system from the American Joint Committee on Cancer (AJCC) is the most commonly used staging system for many cancers, including thyroid cancer, and has been shown to predict differentiated thyroid cancer-related death [1]. While most patients with thyroid carcinoma have well-differentiated tumors that have an excellent prognosis, there are certain characteristics that carry a worse prognosis, including older age, larger primary tumor size, aggressive tumor histology, extrathyroidal tumor extension (ETE), and distant metastasis [2].
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Marcadis, A.R., Cracchiolo, J., Shaha, A.K. (2018). Management of Locally Advanced Thyroid Cancer. In: Parameswaran, R., Agarwal, A. (eds) Evidence-Based Endocrine Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-10-1124-5_8
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DOI: https://doi.org/10.1007/978-981-10-1124-5_8
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