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Abstract

Deviations of systemic acidity in either direction can have adverse consequences and, when severe, can be life-threatening. Therefore, it is essential for the clinician to be able to recognize and properly diagnose acid-base disorders, understand their impact on organ function, and be familiar with their treatment and the potential complications of treatment [1]. Respiratory disorders, that is abnormalities of acid-base equilibrium initiated by a change in blood carbon dioxide tension (PCO2), are frequently encountered in clinical practice, especially in critically ill patients [2]. In the present chapter, we will focus on clinical diagnosis and management of respiratory acidosis and respiratory alkalosis.

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References

  1. Adrogué HJ, Madias NE (1998) Arterial blood gas monitoring: acid-base assessment. In: Tobin MJ (ed) Principles and practice of intensive care monitoring. McGraw-Hill, New York, pp 217–241

    Google Scholar 

  2. Adrogué HJ, Wesson DE (1994) Overview of acid-base disorders. In: Adrogué HJ, Wesson DE (eds) Blackwell’s basics of medicine. Acid-base. Blackwell Science, Boston, pp 49–133

    Google Scholar 

  3. Adrogué HJ, Madias NE (1998) Management of life-threatening acid-base disorders. Part I. N Engl J Med 338:26–34

    Article  PubMed  Google Scholar 

  4. Adrogué HJ, Rashad MN, Gorin AB et al (1989) Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood. N Engl J Med 320:1312–1316

    Article  PubMed  Google Scholar 

  5. Adrogué HJ, Rashad MN, Gorin AB et al (1989) Arteriovenous acid-base disparity in circulatory failure: studies on mechanism. Am J Physiol 257:F1087–F1093

    PubMed  Google Scholar 

  6. Adrogué HJ, Tobin MJ (1997) Management of respiratory failure. In: Adrogué HJ, Tobin MJ (eds) Blackwell’s basics of medicine. Respiratory failure, vol 6. Blackwell Science, Boston, pp 311–331

    Google Scholar 

  7. Tobin MJ (1994) Mechanical ventilation. N Engl J Med 330:1056–1061

    Article  PubMed  CAS  Google Scholar 

  8. Amato MBP, Barbas CSV, Medeiros DM et al (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347–354

    Article  PubMed  CAS  Google Scholar 

  9. Feihl F, Perret C (1994) Permissive hypercapnia: how permissive should we be? Am J Respir Crit Care Med 150:1722–1737

    PubMed  CAS  Google Scholar 

  10. Dries DJ (1995) Permissive hypercapnia. J Trauma 39:984–989

    Article  PubMed  CAS  Google Scholar 

  11. Cardenas VJ, Zwischenberger JB, Tao W et al (1996) Correction of blood pH attenuates changes in hemodynamics and organ blood flow during permissive hypercapnia. Crit Care Med 24:827–834

    Article  PubMed  Google Scholar 

  12. Gentilello LM, Anardi D, Mock C et al (1995) Permissive hypercapnia in trauma patients. J Trauma 39:846–852

    Article  PubMed  CAS  Google Scholar 

  13. Gennari FJ, Kassirer JP (1982) Respiratory alkalosis. In: Cohen JJ, Kassirer JP (eds) Acid-base. Little Brown, Boston, pp 349–376

    Google Scholar 

  14. Adrogué HJ, Madias NE (1998) Management of life-threatening acid-base disorders. Part II. N Engl J Med 338:107–111

    Article  Google Scholar 

  15. Krapf R, Beeler I, Hertner D et al (1991) Chronic respiratory alkalosis: the effect of sustained hyperventilation on renal regulation of acid-base equilibrium. N Engl J Med 324:1394–1401

    Article  PubMed  CAS  Google Scholar 

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© 1999 Springer-Verlag Italia

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Adrogué, H.J. (1999). Respiratory Acidosis and Alkalosis. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-2145-7_40

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  • DOI: https://doi.org/10.1007/978-88-470-2145-7_40

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0051-3

  • Online ISBN: 978-88-470-2145-7

  • eBook Packages: Springer Book Archive

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