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Cefalee

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Terapia delle malattie neurologiche

Riassunto

Fra tutti i sintomi per i quali un medico può essere consultato la cefalea è forse quello più frequente, anche se è di volta in volta diversa nella sua espressione, complessa nella sua manifestazione, e difficile da interpretare secondo un unico meccanismo. In alcuni casi si tratta di un evento occasionale e autolimitato, ma altre volte la cefalea è l’espressione di patologie gravi o assume le caratteristiche di patologia ricorrente e invalidante.

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Bibliografia

  1. Blau JN. Migraine. London: Chapman and Hall Medical; 1987.

    Google Scholar 

  2. Bussone G, Usai S. Malattie del Sistema nervoso: Le Cefalee. In: Zanussi C (ed). Terapia Medica Pratica. 7a Edizione. Torino: UTET; 2002:791–799.

    Google Scholar 

  3. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders. 2nd Edition. Cephalalgia 2004; 24:1–151.

    Google Scholar 

  4. Silberstein SD, Lipton RB, Goadsby PJ. Diagnostic testing and ominous causes of headache. In: Headache in clinical practice. London: Martin Dunitz Ltd; 2002: 35–46.

    Google Scholar 

  5. Olesen J, Dodick WD. The History and Examination of Headache Patients. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:43–53.

    Google Scholar 

  6. Mathew NT, Tfelt-Hansen P. General and Pharmacologic Approach to Migraine Management. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2006; 433-440.

    Google Scholar 

  7. D’Amico D. Treatment strategies in migraine patients. Neurol Sci. 2004; 25 Suppl 3:S242–243.

    Article  PubMed  Google Scholar 

  8. D’Amico D, Moschiano F, Usai S, Bussone G. Treatment strategies in the acute therapy of migraine: stratified care and early intervention. Neurol Sci. 2006; 27 Suppl 2:S117–122.

    Article  PubMed  Google Scholar 

  9. Lantéri-Minet M. What do patients want from their acute migraine therapy? Eur Neurol. 2005; 53 Suppl 1:3–9.

    Article  PubMed  Google Scholar 

  10. Loder E, Biondi D. General principles of migraine management: the changing role of prevention. Headache. 2005; 45 Suppl 1:S33–47.

    Article  PubMed  Google Scholar 

  11. McGrath PJ, Penzien D, Rains JC. Psychological and Behavioral Treatments of Migraines. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:441–448.

    Google Scholar 

  12. Holroyd KA, Martin PR, Nash JM. Psychological Treatments of Tension-Type Headaches. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:711–719.

    Google Scholar 

  13. Bussone G, Grazzi L, D’Amico D, Leone M, et al. Biofeedback-assisted relaxation training for young adolescents with tension-type headache: a controlled study. Cephalalgia 1998; 18:463–467.

    Article  CAS  PubMed  Google Scholar 

  14. Grazzi L, Andrasik F, D’Amico D et al. Electromyographic biofeedback-assisted relaxation training in juvenile episodic tension type headache: clinical outcome at three year follow up. Cephalalgia 2001; 21: 798–893.

    Article  CAS  PubMed  Google Scholar 

  15. Beck AT. Cognitive therapy and the emotional disorders. New York: International University press; 1976.

    Google Scholar 

  16. Holroyd KA, Andrasik F, Westbrook T. Cognitive control of tension headache. Cogn Ter Res 1977; 1:121–33.

    Article  Google Scholar 

  17. Holroyd KA, Penzien DB. Pharmacological versus non-pharmacological prophylaxis of recurrent migraine headache: a meta-analytic review of clinical trials. Pain. 1990; 42(1):1–13.

    Article  CAS  PubMed  Google Scholar 

  18. Blanchard EB, Appelbaum KA, Guarnieri P, Morrill B, Dentinger MP. Five year prospective follow-up on the treatment of chronic headache with biofeedback and/or relaxation. Headache. 1987; 27(10):580–3.

    Article  CAS  PubMed  Google Scholar 

  19. Jensen R, Mills Roth J. Physiotherapy of Tension-Type Headaches. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:721–725.

    Google Scholar 

  20. Tavola T, Gala C, Conte G, Invernizzi G. Traditional Chinese acupuncture in tension-type headache: a controlled study. Pain 1992; 48:325–9.

    Article  CAS  PubMed  Google Scholar 

  21. Karst M, Reinhard M, Thum P et al. Needle acupuncture in tension-type headache: a randomised, placebo-controlled study. Cephalalgia 2001; 21:637–42.

    Article  CAS  PubMed  Google Scholar 

  22. Melchart D, Linde K, Fischer P, Berman B, White A, Vickers A, Allais G. Acupuncture for idiopathic headache. Cochrane Database Syst Rev. 2001; (1):CD001218.

    Google Scholar 

  23. Silberstein SD. Review of botulinum toxin type A and its clinical applications in migraine headache. Expert Opin Pharmacother. 2001; Oct; 2(10):1649–1654.

    Article  CAS  PubMed  Google Scholar 

  24. Freitag FG. Botulinum toxin type A in chronic migraine. Expert Rev Neurother. 2007; 7(5):463–470.

    Article  CAS  PubMed  Google Scholar 

  25. Rapoport AM Sheftell FD, Purdy RA. Advanced Therapy of Headache. Hamilton: B.C. Decker Inc, 1999.

    Google Scholar 

  26. Silberstein S.D., for the US Consortium. Practice parameter: Evidence-based guidelines for migraine headache (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2000; 55:754–63.

    CAS  PubMed  Google Scholar 

  27. Goadsby PJ. The pharmacology of headache. Prog Neurobiol 2000; 62:509–25.

    Article  CAS  PubMed  Google Scholar 

  28. Silberstein SD, Saper JR, Freitag F. Migraine: diagnosis and treatment. In: Silberstein SD, Lipton RB, Dalessio DJ, eds. Wolff’s headache and other head pain. 7th edition. New York: Oxford University Press; 2001.

    Google Scholar 

  29. Rapoport AM, Stewart JT, Bigal ME, Sheftell FD. The triptan formulations. How to mach patients and products. CNS Drug 2003; 17(6):431–447.

    Article  CAS  Google Scholar 

  30. Members of the task force: Evers S, Afra J, Frese A, Goadsby PJ, Linde M, May A, Sandor PS (2006) EFNS guideline on the drug treatment of migraine — report of an EFNS task force. Eur J Neurol. 2006; 13(6):560–572.

    Article  CAS  PubMed  Google Scholar 

  31. Dodick WD, Campbell JK. Cluster Headache: Diagnosis, Management, and Treatment. In:Wolff’s Headache. Edited by Silberstein SD, Lipton RB, Dalessio DJ. 2001; Oxford University Press.

    Google Scholar 

  32. Silberstein SD, Lipton RB. Chronic Daily Headache, Including Transformed Migraine, Chronic Tension-Type Headache, and Medication Overuse. In: Wolff’s Headache. Edited by Silberstein SD, Lipton RB, Dalessio DJ. 2001; Oxford University Press.

    Google Scholar 

  33. Lipton RB, Hamelsky SW, Stewart WF. Epidemiology and impact of headache. In: Wolff’s Headache. Edited by Silberstein SD, Lipton RB, Dalessio DJ. Oxford University Press, 2001.

    Google Scholar 

  34. Jensen R, Stovner LJ. Epidemiology and comorbidity of headache. Lancet Neurol 2008; 7(4):354–361.

    Article  PubMed  Google Scholar 

  35. Lipton RB, Hamelsky SW, Stewart WF. Epidemiology and impact of headache. In: Wolff’s Headache. Edited by Silberstein SD, Lipton RB, Dalessio DJ. Oxford University Press 2001.

    Google Scholar 

  36. Clarke CE, MacMillan L, Sondhi S, Wells NE. Economic and social impact of migraine. Q L Med 1996; 89:77–84.

    CAS  Google Scholar 

  37. Stewart WF, Lipton RB, Simon D. Work-related disability: results from the American migraine study. Cephalalgia, 1996; 16(4):215.

    Google Scholar 

  38. Stewart WF, Lipton RB, Whyte J et al. An international study to assess the reliability of the Migraine Disability Assessment (MIDAS) score. Neurology 1999; 53:988–994.

    CAS  PubMed  Google Scholar 

  39. D’Amico D, Mosconi P, Genco S et al. Reliability of Italian translation of migraine disability assessment (MIDAS) questionnaire. Cephalalgia 2000; 20:317.

    Google Scholar 

  40. Terwindt GM, Ferrari MD, Tijhuis M et al. The impact of migraine on quality of life in the general population: the GEM study. Neurology. 2000; Sep 12;55(5):624–629.

    CAS  PubMed  Google Scholar 

  41. Bussone G, Usai S, Grazzi L et al. Disability and quality of life in different primary headaches: results from Italian studies. Neurol Sci. 2004; Oct 25 Suppl 3:S105–107.

    Article  Google Scholar 

  42. Osterhaus JT, Townsend RJ, Gandeck B et al. Measuring the functional status and well-being of patients with migraine headache. Headache 1994; 34:337–343.

    Article  CAS  PubMed  Google Scholar 

  43. Leonardi M, Steiner TJ, Scher AT, Lipton RB.The global burden of migraine: measuring disability in headache disorders with WHO’s Classification of Functioning, Disability and Health (ICF). J Headache Pain. 2005; 6(6):429–440.

    Article  PubMed  Google Scholar 

  44. Ruskell GL, Simons T. Trigeminal nerve pathways to the cerebral arteries in monkeys. J Anat 1987; 155:23–37.

    CAS  PubMed  Google Scholar 

  45. Liu-Chen LY, Mayberg MR, Moskowitz MA. Immunohistochemical evidence for substance P containing trigeminovascular pathway to pial arteries in cats. Brain Res 1983; 268:162–166.

    Article  CAS  PubMed  Google Scholar 

  46. Goadsby PJ, Edvinsson L, Ekman R. Release of vasoactive peptides in the extracerebral circulation of man. Ann Neurol 1988; 23:193–196.

    Article  CAS  PubMed  Google Scholar 

  47. Moskowitz MA, Cutrer FM. Sumatriptan: a receptortargeted treatment for migraine. Ann Rev Med 1993; 44:145–154.

    Article  CAS  PubMed  Google Scholar 

  48. Markowitz S, Saito K, Moskowitz MA. Neurogenically mediated plasma extravasation in dura mater: effect of ergot alkaloids. A possible mechanism of action in vascular headache. Cephalalgia 1988; 8:83–91.

    Article  CAS  PubMed  Google Scholar 

  49. Burstein R, Yamamura H, Malick A, Strassman AM. Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. J Neurophysiol 1998; 79:964–983.

    CAS  PubMed  Google Scholar 

  50. Burstein R, Yarnitsky D, Goor-Aryeh I et al. An association between migraine and cutaneous allodynia. Ann Neurol 2000; 47:614–624.

    Article  CAS  PubMed  Google Scholar 

  51. Burstein R, Cutrer MF, Yarnitsky D. The development of cutaneous allodynia during a migraine attack clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine. Brain. 2000; 123 (Pt 8):1703–1709.

    Article  PubMed  Google Scholar 

  52. Landy S, Rice K, Lobo B. Central sensitisation and cutaneous allodynia in migraine: implications for treatment. CNS Drugs. 2004; 18(6):337–342.

    Article  PubMed  Google Scholar 

  53. Burstein R, Jakubowski M. Analgesic triptan action in an animal model of intracranial pain: a race against the development of central sensitization. Ann Neurol. 2004; 55(1):27–36.

    Article  CAS  PubMed  Google Scholar 

  54. Welch KMA, D’Andrea G, Tepley N et al. The concept of migraine as a state of central neuronal hyperexcitability. Neurol Clin 1990; 8:817–828.

    CAS  PubMed  Google Scholar 

  55. Welch KMA, Ramadan NM. Mithocondria, magnesium and migraine. J Neurol Sci 1995; 134:9–14.

    Article  CAS  PubMed  Google Scholar 

  56. Ramadan NM, Halvorson H, Vande-Linde A, Levine SR, Helpern JA, Welch KM. Low brain magnesium in migraine. Headache. 1989; 29(9):590–593.

    Article  CAS  PubMed  Google Scholar 

  57. Olesen J. Cerebral and extracranial circulatory disturbances in migraine: pathophysiological implications. Cerebrovasc Brain Metab Rev 1991; 3:1–28.

    CAS  PubMed  Google Scholar 

  58. Cutrer FM, O’Donnell A, Sanchez del Rio M. Functional neuroimaging: enhanced understanding of migraine pathophysiology. Neurology 2000; 55(9 Suppl 2):S36–45.

    CAS  PubMed  Google Scholar 

  59. Cutrer FM, Huerter K. Migraine aura. Neurologist. 2007; 13(3):118–125.

    Article  PubMed  Google Scholar 

  60. Joutel A, Bausser MG, Biousee V. A gene for familial hemiplegic migraine maps to chromosome 19. Nat Genet 1993; 5:40–45.

    Article  CAS  PubMed  Google Scholar 

  61. Vahedi K, Joutel A, Van Bogaert P. A gene for hereditary paroxysmal cerebellar ataxia maps to chromosome 19p. Ann Neurol 1995; 37: 289–293.

    Article  CAS  PubMed  Google Scholar 

  62. Loder E, Harrington MG, Cutrer M, Sandor P, De Vries B. Selected confirmed, probable, and exploratory migraine biomarkers. Headache 2006; 46(7):1108–127.

    Article  PubMed  Google Scholar 

  63. Goadsby PJ. Migraine pathophysiology.Headache 2005; 45 Suppl 1:S14–24.

    Article  PubMed  Google Scholar 

  64. Burstein R, Jakubowski M. Unitary hypothesis for multiple triggers of the pain and strain of migraine. J Comp Neurol. 2005; 493(1):9–14.

    Article  PubMed  Google Scholar 

  65. Saxena PR, Tfelt-Hansen P. Triptans, 5HT1B/1D. Receptor Agonists in the Acute Treatment of Migraine. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:469–503.

    Google Scholar 

  66. Gardner DM, Lynd LD. Sumatriptan contraindications and the serotonin syndrome. Ann Pharmacother 1998; 32:33–38.

    Article  CAS  PubMed  Google Scholar 

  67. Lipton RB. Disability assessment as a basis for stratified care. Cephalalgia 1998; 18 (suppl 22): 40–46.

    PubMed  Google Scholar 

  68. Lipton RB, Stewart WF, Stone AM, Lainez MJ, Sawyer JP; Disability in Strategies of Care Study group. Stratified care us step care strategies for migraine: the Disability in Strategies of Care (DISC) Study: A randomized trial. JAMA. 2000; 284(20):2599–2605.

    Article  CAS  PubMed  Google Scholar 

  69. Ferrari MD, Goadsby PJ, Roon KI, Lipton RB. Triptans (serotonin, 5-HT1B/1D agonists) in migraine: detailed results and methods of a meta-analysis of 53 trials. Cephalalgia. 2002; 22(8):633–658.

    Article  CAS  PubMed  Google Scholar 

  70. Cady RK, Lipton RB, Hall C, Stewart WF, O’Quinn S, Gutterman D. Treatment of mild headache in disabled migraine sufferers: results of the Spectrum Study. Headache 200; 40(10),792–797.

    Article  Google Scholar 

  71. Dowson AJ, Mathew NT, Pascual J. Review of clinical trials using early acute intervention with oral triptans for migraine management. Int J Clin Pract 2006; 60(6):698–706.

    Article  CAS  PubMed  Google Scholar 

  72. Krymchantowski AV, Bigal ME (2006) Polytherapy in the preventive and acute treatment of migraine: fundamentals for changing the approach. Expert Rev Neurother; 6(3):283–289.

    Article  CAS  PubMed  Google Scholar 

  73. Tfelt-Hansen P, Rolan P. β-Adrenoceptor Blocking Drugs in Migraine Prophylaxis. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:519–537.

    Google Scholar 

  74. Diamond S, Medina JL. Double blind study of propranolol for migraine prophylaxis. Headache 1976; 16(1):24–27.

    Article  CAS  PubMed  Google Scholar 

  75. Pradalier A, Serratrice G, Collard M, Hirsch E, Feve J, Masson M, Masson C, Dry J, Koulikovsky G, Nguyen G. Long-acting propranolol in migraine prophylaxis: results of a double-blind, placebo-controlled study. Cephalalgia 1989; 9(4):247–253.

    Article  CAS  PubMed  Google Scholar 

  76. Tfelt-Hansen P, Saxena PR. Antiserotonin Drugs in Migraine Prophylaxis. In:The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:529–537.

    Google Scholar 

  77. Couch JR, Hassanein RS. Amitriptyline in migraine prophylaxis. Arch Neurol 1979; 36:695–699.

    CAS  PubMed  Google Scholar 

  78. Asakura K, Kanemasa T, Minagawa K, Kagawa K, Yagami T, Nakajima M, Ninomiya M. Alpha-eudesmol, a P/Q-type Ca(2+) channel blocker, inhibits neurogenic vasodilation and extravasation following electrical stimulation of trigeminal ganglion. Brain Res. 2000; 873(1):94–101.

    Article  CAS  PubMed  Google Scholar 

  79. Louis P. A double-blind placebo-controlled prophylactic study of flunarizine (Sibelium) in migraine. Headache 1981; 21(6):235–239.

    Article  CAS  PubMed  Google Scholar 

  80. Sørensen PS, Hansen K, Olesen J. A placebo-controlled, double-blind, cross-over trial of flunarizine in common migraine. Cephalalgia 1986;6(1):7–14.

    Article  PubMed  Google Scholar 

  81. Sorge F, De Simone R, Marano E, Nolano M, Orefice G, Carrieri P. Flunarizine in prophylaxis of childhood migraine. A double-blind, placebo-controlled, crossover study. Cephalalgia 1988; 8(1):1–6.

    Article  CAS  PubMed  Google Scholar 

  82. Micheli FE, Pardal MM, Giannaula R, Gatto M, Parera I, Paradiso G, Torres M, Pikielny R, Pardal J. Movement disorders and depression due to flunarizine and cinnarizine. Mov Disord. 1989; 4(2):139–146.

    Article  CAS  PubMed  Google Scholar 

  83. Toda N, Tfelt-Hansen P. Calcium Antagonists in Migraine Prophylaxis. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:539–544.

    Google Scholar 

  84. Silberstein SD, Tfelt-Hansen P. Antiepileptic Drugs in Migraine Prophylaxis. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:545–551.

    Google Scholar 

  85. D’Amico D. Antiepileptic drugs in the prophylaxis of migraine, chronic headache forms and cluster headache: a review of their efficacy and tolerability. Neurol Sci. 2007; 28 Suppl 2:S188–197.

    Article  PubMed  Google Scholar 

  86. Hering R, Kuritzky A. (1992) Sodium valproate in the prophylactic treatment of migraine: a double-blind study versus placebo. Cephalalgia; 12(2):81–4.

    Article  CAS  PubMed  Google Scholar 

  87. Jensen R, Brinck T, Olesen J. (1994) Sodium valproate has a prophylactic effect in migraine without aura: a triple-blind, placebo-controlled crossover study. Neurology; 44(4):647–651.

    CAS  PubMed  Google Scholar 

  88. Mathew NT, Saper JR, Silberstein SD, Rankin L, Markley HG, Solomon S, Rapoport AM, Silber CJ, Deaton RL. (1995) Migraine prophylaxis with divalproex. Arch Neurol; 52(3):281–286.

    CAS  PubMed  Google Scholar 

  89. Klapper J. (1997) Divalproex sodium in migraine prophylaxis: a dose-controlled study. Cephalalgia Apr; 17(2):103–108.

    Article  CAS  Google Scholar 

  90. Freitag FG, Collins SD, Carlson HA, Goldstein J, Saper J, Silberstein S, Mathew N, Winner PK, Deaton R, Sommerville K, Depakote ER (2002) Migraine Study Group. A randomized trial of divalproex sodium extended-release tablets in migraine prophylaxis. Neurology; 58(11):1652–1659.

    Google Scholar 

  91. Silberstein SD, Collins SD. (1999) Safety of divalproex sodium in migraine prophylaxis: an open-label, long-term study. Long-term Safety of Depakote in Headache Prophylaxis Study Group Headache; 39(9):633–643.

    CAS  Google Scholar 

  92. Silberstein SD, Neto W, Schmitt J, et al. (2004) Topiramate in migraine prevention: results of a large controlled trial. Arch Neurol; 61:490–495.

    Article  PubMed  Google Scholar 

  93. Brandes JL, Saper JR, Diamond M, et al. Topiramate for migraine prevention: a randomized controlled trial. JAMA 2004; 291:965–73.

    Article  CAS  PubMed  Google Scholar 

  94. Diener HC, Tfelt-Hansen P, Dahlof C, et al. Topiramate in migraine prophylaxis. Results from a placebo-controlled trial with propranolol as an active control. J Neurol 2004; 251:943–950.

    Article  CAS  PubMed  Google Scholar 

  95. Bussone G, Diener HC, Pfeil J, et al. (2005) Topiramate 100 mg/day in migraine prevention: a pooled analysis of double-blind randomised controlled trials. Int J Clin Pract; 59:961–968.

    Article  CAS  PubMed  Google Scholar 

  96. Silberstein SD, Ben-Menachem E, Shank RP, et al. (2005) Topiramate monotherapy in epilepsy and migraine prevention. Clin Ther; 27:154–165.

    Article  CAS  PubMed  Google Scholar 

  97. Rapoport A, Mauskop A, Diener HC, Schwalen S, Pfeil J.(2006) Long-term migraine prevention with topiramate: open-label extension of pivotal trials. Headache; 46(7):1151–1160.

    Article  PubMed  Google Scholar 

  98. Diener HC, Agosti R, Allais G, Bergmans P, Bussone G, Davies B, Ertas M, Lanteri — Minet, Reuter U, Del Rio MS, Schoenen J, Schwalen S, van Oene J; TOPMAT-MIG-303. Investigators Group. Cessation versus continuation of 6-month migraine preventive therapy with topiramate (PROMPT): a randomised, double-blind, placebo-controlled trial. Lancet Neurol 2007; 6(12):1054–1062.

    Article  CAS  PubMed  Google Scholar 

  99. Dahlof C Loder E, Diamond M, Rupnow M, Papadopoulos G, Mao L. The impact of migraine prevention on daily activities: a longitudinal and responder analysis from three topiramate placebo-controlled clinical trials. Health Qual Life Outcomes 2007; 4;5(1):56.

    Article  PubMed  Google Scholar 

  100. Brandes JL, et al. Assessing the ability of topiramate to improve the daily activities of patients with migraine. Mayo Clin Proc 2006; 81(10):1311–1319.

    Article  CAS  PubMed  Google Scholar 

  101. Di Trapani G, Mei D, Marra C et al. Gabapentin in the prophylaxis of migraine: a double-blind randomized placebo-controlled study. Clin Ter 2000; 151(3):145–148.

    PubMed  Google Scholar 

  102. Mathew NT, Rapoport A, Saper J, Magnus L, Klapper J, Ramadan N, Stacey B, Tepper S. (2001) Efficacy of gabapentin in migraine prophylaxis. Headache; 41(2):119–128.

    Article  CAS  PubMed  Google Scholar 

  103. D’Andrea G, Granella F, Cadaldini M, Manzoni GC. (1999) Effectiveness of lamotrigine in the prophylaxis of migraine with aura: an open pilot study. Cephalalgia; 19(1):64–66.

    Article  PubMed  Google Scholar 

  104. Pascual J, Caminero AB, Mateos V, Roig C, Leira R, Garcia-Monco C, Lainez MJ. (2004) Preventing disturbing migraine aura with lamotrigine: an open study. Headache; 44(10):1024–8.

    Article  PubMed  Google Scholar 

  105. Lampl C, Katsarava Z, Diener HC et al. Lamotrigine reduces migraine aura and migraine attacks in patients with migraine with aura. J Neurol Neurosurg Psychiatry; 2005; 76(12):1730–2.

    Article  CAS  PubMed  Google Scholar 

  106. Calabresi P, Galletti F, Rossi C, Sarchielli P, Cupini LM. Antiepileptic drugs in migraine: from clinical aspects to cellular mechanisms. Trends Pharmacol Sci. 2007; 28(4):188–195.

    Article  CAS  PubMed  Google Scholar 

  107. Welch KM, Ellis DJ, Keenan PA. Successful migraine prophylaxis with naproxen sodium. Neurology 1985; 35(9):1304–1310.

    CAS  PubMed  Google Scholar 

  108. Nelson-Piercy C, De Swiet M. Diagnosis and management of migraine. Low dose aspirin may be used for prophylaxis. BMJ 1996; 313(7058):691–692.

    CAS  PubMed  Google Scholar 

  109. Sances G, Martignoni E, Fioroni L et al. Naproxen sodium in menstrual migraine prophylaxis: a doubleblind placebo controlled study. Headache 1990; 30(11):705–709.

    Article  CAS  PubMed  Google Scholar 

  110. Silberstein SD, Lipton RB, Sliwinski M. Classification of daily and near-daily headaches. Neurology 1996; 47:871–875.

    CAS  PubMed  Google Scholar 

  111. D’Amico D, Tullo V, Proietti Cecchini A. Application of revised criteria fo Chronic Migraine and Medication Overuse headache in a tertiary care Headache Centre. Neurol Sci 2008; 29:S158–S160.

    Article  PubMed  Google Scholar 

  112. Headache Classification Committee of the International Headache Society. New appendix criteria open for a broader concept of chronic migraine. Cephalalgia 2006; 26:742–746.

    Article  Google Scholar 

  113. Mathew NT, Kurman R, Perez F. Drug induced refractory headache-clinical features and management. Headache. 1990;30(10):634–638.

    Article  CAS  PubMed  Google Scholar 

  114. Silberstein SD, Lipton RB. Chronic Daily Headache, Including Transformed Migraine, Chronic Tensio-Type Headache, and Medication Overuse. In:Wolff’s Headache and Other Head Pain, 7th edition, Silberstein SD, Lipton RB, Dalessio DJ, Eds, Oxford University Press 2001.

    Google Scholar 

  115. Bigal ME, Rapoport AM, Sheftell FD, Tepper SJ, Lipton RB (2004) Transformed migraine and medication overuse in a tertiary headache centre — clinical characteristics and treatment outcomes. Cephalalgia; 24: 483–490.

    Article  CAS  PubMed  Google Scholar 

  116. Grazzi L, Andrasik F. Medication-overuse headache: description treatment and relapse prevention. Current Pain and Headache Reports 2006; 10: 71–77.

    Article  PubMed  Google Scholar 

  117. Scher AI, Midgette LA, Lipton RB. Risk factors for headache chronification. Headache 2008; 48(1):16–25.

    PubMed  Google Scholar 

  118. Freitag FG, Lake A 3rd, Lipton R et al. US Headache Guidelines Consortium, Section on Inpatient Treatment Chairpersons. Inpatient treatment of headache: an evidence-based assessment. Headache 2004; 44(4):342–360.

    Article  PubMed  Google Scholar 

  119. Katsarava Z, Muessig M, Dzagnidze A. Medication overuse headache: rates and predictors for relapse in a 4-year prospective study. Cephalalgia 2005; 25(1):12–15.

    Article  CAS  PubMed  Google Scholar 

  120. Mathew NT The prophylactic treatment of chronic daily headache. Headache 2006; 46: 1552–1564.

    Article  PubMed  Google Scholar 

  121. Andrasik F, Grazzi L, Usai S. Disability in Chronic Migraine With Medication Overuse: Treatment Effects at 3 Years. Headache 2007; 47(9):1277–1281.

    Article  PubMed  Google Scholar 

  122. Zeegerg P, Olesen J, Jensen R. Probable medicationoveruse headache: the effect of a 2-month drug-free period. Neurology 2006; 66(12):1894–1898.

    Article  Google Scholar 

  123. Krymchantowski AV, Silva MT, Barbosa JS et al. Amitriptyline versus amitriptyline combined with fluoxetine in the preventative treatment of transformed migraine: a double-blind study. Headache 2002; 42(6):510–514.

    Article  PubMed  Google Scholar 

  124. Saper JR, Lake AE 3rd, Cantrell DT et al. Chronic daily headache prophylaxis with tizanidine: a doubleblind, placebo-controlled, multicenter outcome study. Headache 2002; 42(6):470–482.

    Article  PubMed  Google Scholar 

  125. Saper JR, Silberstein SD, Lake AE 3rd et al. Doubleblind trial of fluoxetine: chronic daily headache and migraine. Headache 1994; 34(9):497–502.

    Article  CAS  PubMed  Google Scholar 

  126. Spira PJ, Beran RG; Australian Gabapentin Chronic Daily Headache Group.Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebocontrolled study. Neurology 2003; 61(12):1753–1759.

    CAS  PubMed  Google Scholar 

  127. Silvestrini M, Bartolini M, Coccia M et al. Topiramate in the treatment of chronic migraine. Cephalalgia 2003; 23(8):820–824.

    Article  CAS  PubMed  Google Scholar 

  128. Silberstein SD, Lipton RB, Dodick DW et al. Topiramate Chronic Migraine Study Group. Efficacy and safety of topiramate for the treatment of chronic migraine: a randomized, double-blind, placebo-controlled trial. Headache 2007; 47(2):170–180.

    Article  PubMed  Google Scholar 

  129. Diener HC, Bussone G, Van Oene JC et al. TOPMATMIG-201(TOP-CHROME) Study Group. Topiramate reduces headache days in chronic migraine: a randomized, double-blind, placebo-controlled study. Cephalalgia 2007; 27(7):814–823.

    Article  PubMed  Google Scholar 

  130. Dodick DW, Silberstein S, Saper J et al. The impact of topiramate on health-related quality of life indicators in chronic migraine. Headache 2007; 47(10):1398–1408.

    PubMed  Google Scholar 

  131. Meletiche DM, Lofland JH, Young WB. Quality-of-life differences between patients with episodic and transformed migraine. Headache 2001; 41(6):573–578.

    Article  CAS  PubMed  Google Scholar 

  132. D’Amico D, Grazzi L, Usai S et al. Disability pattern in chronic migraine with medication overuse: a comparison with migraine without aura. Headache. 2005 May; 45(5):553–560.

    Article  PubMed  Google Scholar 

  133. Rasmussen BK, Jensen R, Schroll M, Olesen J. Epidemiology of tension-type headache in a general population-a prevalence study. J Clin Epidemio 1991; 44:1147–1157.

    Article  CAS  Google Scholar 

  134. Gobel H, Petersen-Braun M, Soyka D.The epidemiology of headache in Germany: a nationwide survey of a representative sample n the basis of the headache classification of the International Headache Society 1994; 14(2):97–106.

    CAS  Google Scholar 

  135. Lavados PM, Tenhamn E. Epidemiology of tensiontype headache in Santiago, Chile: a prevalence study. Cephalalgia 1998; 18(8):552–558.

    Article  CAS  PubMed  Google Scholar 

  136. Schwartz BSm Stewart WF, Simon D, Lipton RB (1998) Epidemiology of tension-type headache. JAMA 279(5):381–383.

    Article  CAS  PubMed  Google Scholar 

  137. Lyngberg AC, Rasmussen BK, Jorgensen T et al. Prognosis of migraine and tension-type headache: a population-based follow-up study. Neurology 2005; 65(4):580–585.

    Article  PubMed  Google Scholar 

  138. Spierings EL. Ranke AH, Honjoop PC. Precipitatine factors of migraine versus tension-type headache. Headache 2001; 41(6):554–558.

    Article  CAS  PubMed  Google Scholar 

  139. Jensen R. Pathophysiological mechanisms of tensiontype headache: a review of epidemiological and experimental studies.Cephalalgia. 1999;19(6):602–621.

    Article  CAS  PubMed  Google Scholar 

  140. Langemark M, Bach FW, Jensen TS, Olesen J. Decreased nociceptive flexion reflex threshold in chronic tensiontype headache. Arch Neurol 1993; 50(10):1061–1064.

    CAS  PubMed  Google Scholar 

  141. Bendsten L. Central sensitization in tension-type-headache-possible pathophysiological mechanisms. Cephalalgia 2000; 20:486–508.

    Article  Google Scholar 

  142. Schoenen J. Tension-type headache: pathophysiologic evidence for a disturbance of “limbic” pathways to the brain stem. Headache 1990; 30:314–315.

    Google Scholar 

  143. Silberstein SD, Lipton RB, Goadsby PJ. Tension type headache: diagnosis and treatment. In: Headache in clinical practice. London: Martin Dunitz Ltd; 2002: 113–128.

    Google Scholar 

  144. D’Amico D, Grazzi L, Leone M, Moschiano F, Bussone G. A review of the treatment of primary headaches. Part II: Tension-type headache. Ital J Neurol Sci 1998; 19(1):2–9.

    Article  PubMed  Google Scholar 

  145. Mathew NT, Ashina M. Acute Pharmacotherapy of Tension-Type Headaches. In: The Headaches 3rd Edition. Philadelphia: Lippincott Williams & Wilkins; 2006:727–733.

    Google Scholar 

  146. Pfanferrath V, Diener HC, Isler H et al. Efficacy and tolerability of amitriptylinoxide in the treatment of chronic tension-type headache: a multicentre controlled study. Cephalalgia 1994; 14:149–155.

    Article  Google Scholar 

  147. Bendtsen L, Jensen R, Olesen J. A nonselective (amitriptyline), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache. J Neurol Neurosurg Psychiatr 1996; 61:285–290.

    Article  CAS  PubMed  Google Scholar 

  148. Holroyd KA, O’Donnel FJ, Stensland M et al. Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomised controlled trial. JAMA 2001; 285:2208–2216.

    Article  CAS  PubMed  Google Scholar 

  149. Langemark M, Loldrup D, Bech P, Olesen J. Clomipramine and mianserin in the treatment of chronic tension headache. A double-blind, controlled study. Headache. 1990;30(3):118–21.

    Article  CAS  PubMed  Google Scholar 

  150. Langemark M, Olesen J. Sulpiride and paroxetine in the treatment of chronic tension-type headache. An exploratory double-blind trial. Headache 1994; 34: 20–24.

    Article  CAS  PubMed  Google Scholar 

  151. Manna V, Bolino F, Di Cicco L. Chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine. Headache. 1994 Jan; 34(1):44–49.

    Article  CAS  PubMed  Google Scholar 

  152. Moja PL, Cusi C, Sterzi RR, Canepari C. Selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headaches. Cochrane Database System 2005 Jul 20; (3):CD002919.

    Google Scholar 

  153. Bendtsen L, Jensen R. Mirtazapine is effective in the prophylactic treatment of chronic tension-type headache. Neurology. 2004 May 25;62(10):1706–1711.

    CAS  PubMed  Google Scholar 

  154. Fogelholm R, Murros K. Tizanidine in chronic tensiontype headache: a placebo controlled double-blind crossover study. Headache 1992; 32(10):509–513.

    Article  CAS  PubMed  Google Scholar 

  155. Murros K, Kataja M, Hedman C, Havanka H, Säkö E, Färkkilä M, Peltola J, Keränen T. Modified-release formulation of tizanidine in chronic tension-type headache. Headache 2000; 40(8):633–637.

    Article  CAS  PubMed  Google Scholar 

  156. Mathew NT, Ali S. Valproate in the treatment of persistent chronic daily headache. An open label study. Headache 1991; 31: 71–74.

    Article  CAS  PubMed  Google Scholar 

  157. Lampl C, Marecek S, May A, Bendtsen L. A prospective, open-label, long-term study of the efficacy and tolerability of topiramate in the prophylaxis of chronic tension-type headache. Cephalalgia 2006; 26(10):1203–1208.

    Article  CAS  PubMed  Google Scholar 

  158. Tonon C, Guttmann S, Volpini M, Naccarato S, Cortelli P, D’Alessandro R. Prevalence and incidence of cluster headache in the Republic of San Marino. Neurology 2002; 58: 1407–1409.

    CAS  PubMed  Google Scholar 

  159. Manzoni GC. Male preponderance of cluster headache is progressively decreasing over the years. Headache 1997; 37(9):588–589.

    Article  CAS  PubMed  Google Scholar 

  160. Russell MB. Epidemiology and geneti cs of cluster headache. Lancet Neurol 2004; 3:279–283.

    Article  PubMed  Google Scholar 

  161. Russell MB. Genetic epidemiology of migraine and cluster headache. Cephalalgia 1997; 17:683–701.

    Article  CAS  PubMed  Google Scholar 

  162. Leone M, Russell MB, Rigamonti A, Attanasio A, Grazzi L, D’Amico D, Usai S, Bussone G. Increased familial risk of cluster headache. Neurology 2001; 56(9):1233.

    CAS  PubMed  Google Scholar 

  163. Leone M, Rigamonti A, Russell MB, Mea E, Bussone. Selective versus complete family interview for detecting affected in familial cluster headache Cephalalgia 2004; 24:938–939.

    Article  CAS  PubMed  Google Scholar 

  164. Baumber L, Sjöstrand C, Leone M, Harty H, Bussone G, Hillert J, Trembath R, Russell MB. A genome-wide scan and hcrtr2 candidate gene analysis in a european cluster headache cohort. Neurology 2006; 66:1888–1893.

    Article  CAS  PubMed  Google Scholar 

  165. Kudrow L. Cluster Headache, Mechanism and Management. In. 1 ed. New York: Oxford University Press; 1980.

    Google Scholar 

  166. Leone M. Chronic Cluster headache: new and emerging treatment options. Curr Pain Head Rep 2004; 8: 347–352.

    Article  Google Scholar 

  167. Leone M, Franzini A, Proietti Cecchini A, Broggi G, Bussone G. Stimulation of occipital nerve for drugresistant chronic cluster headache. Lancet Neurol 2007; 6(4):289–291.

    Article  PubMed  Google Scholar 

  168. Leone M, Curone M, Mea E, Bussone G. Cluster-tic syndrome resolved by removal of pituitary adenoma: the first case. Cephalalgia 2004; 24:1088–1089.

    Article  CAS  PubMed  Google Scholar 

  169. Goadsby PJ, Edvinsson L. Human in vivo evidence for trigeminovascular activation in cluster headache. Brain 1994; 117:427–434.

    Article  PubMed  Google Scholar 

  170. Moskowitz MA. Basic mechanisms in vascular headache. Neurol Clin 1990; 8:801–815

    CAS  PubMed  Google Scholar 

  171. Buzzi MG, Moskowitz MA.The trigemino-vascular system and migraine. Pathol Biol (Paris) 1992; 40(4): 313–317.

    CAS  Google Scholar 

  172. Goadsby PJ, Duckworth JW. Effect of stimulation of trigeminal ganglion on regional cerebral blood flow in cats. Am J Physiol 1987; 253:270–274.

    Google Scholar 

  173. May A, Kaube H, Buchel L et al. Trigeminal transmitted pain using capsaicin: a PET study. Cephalalgia 1997; 17:377.

    Google Scholar 

  174. Bussone G, Leone M. Peccarisi C et al. Double blind comparison of lithium and verapamil in Cluster Headache prophylaxis. Headache 1990; 30:411–417.

    Article  CAS  PubMed  Google Scholar 

  175. Leone M, D’Amico D, Frediani F et al. Verapamil in the prophylaxis of episodic cluster headache: A double-blind study versus placebo. Neurology 2000; 54:1382–1385.

    CAS  PubMed  Google Scholar 

  176. Giannini AJ, Loiselle RH. Verapamil maintenance therapy in bipolar patients. J Clin Psychiatry 1996; 57 (3):136.

    CAS  PubMed  Google Scholar 

  177. Leone M, Bussone G. A review of hormonal findings in cluster headache. Evidence for hypothalamic involvement. Cephalalgia 1993; 13:309–317.

    Article  CAS  PubMed  Google Scholar 

  178. Leone M, Lucini V, D’Amico D et al. Alterations in the circadian production of melatonin and cortisol in cluster headache. In: Clifford-Rose (ed) New advances in headache research 4. Smith-Gordon, London, 1994:211–219.

    Google Scholar 

  179. Leone M, Lucini V, D’Amico D et al. Abnormal 24-hour urinary excretory pattern of 6-sulphatoxymelatonin in both phases of cluster headache. Cephalalgia 1998; 18:664–667.

    Article  CAS  PubMed  Google Scholar 

  180. Malick A, Strassman AM, Burstein R. Trigeminohypothalamic and reticulohypothalamic tract neurons in the upper cervical spinal cord and caudal medulla of the rat. J Neurophysiol. 2000;84:2078–2112.

    CAS  PubMed  Google Scholar 

  181. Bartsch T, Levy MJ, Knight YE, Goadsby PJ. Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area. Pain. 2004; 109:367–378.

    Article  CAS  PubMed  Google Scholar 

  182. Leone M and Bussone G. Melatonin in cluster headache: rationale for use and possible therapeutic potential. CNS Drugs 1998; 9:7–16.

    Article  CAS  Google Scholar 

  183. May A, Bahra A, Buchel C et al. Hypothalamic activation in cluster headache attacks. Lancet 1998; 352:275–278.

    Article  CAS  PubMed  Google Scholar 

  184. Sprenger T, Boecker H, Toelle TR et al. Specific hypothalamic activation during a spontaneous cluster headache attack. Neurology 2004; 3(62):516–517.

    Google Scholar 

  185. May A, Ashburner J, Buchel C et al. Correlation between structural and functional changes in brain in an idiopathic headache syndrome. Nat Med. 1999; 5:836–838.

    Article  CAS  PubMed  Google Scholar 

  186. Lodi R, Pierangeli G, Tonon C et al. Study of hypothalamic metabolism in cluster headache by proton MR spectroscopy. Neurology 2006 25; 66(8):1264–1266.

    Article  CAS  PubMed  Google Scholar 

  187. Wang SJ, Lirng JF, Fuh JL, Chen JJ. Reduction in hypothalamic 1H-MRS metabolite ratios in patients with cluster headache. J Neurol Neurosurg Psychiatry 2006; 77:622–662.

    Article  PubMed  Google Scholar 

  188. Leone M, Franzini A, Bussone G. Stereotactic stimulation of posterior hypothalamic gray matter for intractable cluster headache. NEJM 2001; 345(19): 1428–1429.

    Article  CAS  PubMed  Google Scholar 

  189. May A, Leone M, Boecker H, Sprenger T, Juergens T, Bussone G, Toelle TR. Hypothalamic deep brain stimulation in PET. J Neurosci 2006; 26 (13):3589–3593.

    Article  CAS  PubMed  Google Scholar 

  190. Leone M. Deep brain stimulation in headaches. Lancet Neurology 2006; 5:873–877.

    Article  PubMed  Google Scholar 

  191. Leone M, Franzini A, Broggi G et al. Acute hypothalamic stimulation and ongoing cluster headache attacks. Neurology 2006; 67(10):1844–1845.

    Article  CAS  PubMed  Google Scholar 

  192. Jürgens T, Busch V, Leone M et al. Modulation des nociceptiven Systems durch Tiefenhirnstimulation des posterioren Hypothalamus bei Clusterkopfschmerz. Schmerz 2007; Suppl 1:104–105.

    Google Scholar 

  193. Leone M, Proietti Cecchini A, Franzini A et al. Lessons from eight years’ experience of hypothalamic stimulation in cluster headache. Head Curr 2008. In press.

    Google Scholar 

  194. Leone M, Mea E, Genco S, Bussone G. Coexistence of TACs and trigeminal neuralgia: pathophysiological conjectures Headache 2006; 46 (10):1565–1570.

    Article  PubMed  Google Scholar 

  195. May A, Bahra A, Buchel C et al. Functional MRI in spontaneous attacks of SUNCT: short-lasting neuralgiform headache with conjunctival injection and tearing. Ann Neurol 1999; 46:791–793.

    Article  CAS  PubMed  Google Scholar 

  196. Matharu MS, Cohen AS, Frackowiak RSJ, Goadsby PJ. Posterior hypothalamic activation in paroxysmal hemicrania. Ann Neurol 2006; 59:535–545.

    Article  PubMed  Google Scholar 

  197. Leone M, Franzini A, D’Andrea G et al. Deep brain stimulation to relieve severe drug-resistant SUNCT. Ann Neurol 2005; 57:924–927.

    Article  PubMed  Google Scholar 

  198. Gobel H, Lindner V, Heinze A, Ribbat M, Deuschl G. Acute therapy for cluster headache with sumatriptan: findings of a one-year long-term study. Neurology 1998; 51:908–911.

    CAS  PubMed  Google Scholar 

  199. Steiner TJ, Hering R, Couturier EGM, Davies PTG, Whitmarsh TE. Double-blind placebo-controlled trial of lithium in episodic cluster headache. Cephalalgia 1997; 17:673–675.

    Article  CAS  PubMed  Google Scholar 

  200. Prusinsky A, Kozubsky W, Szulc-Kuberska J. Steroid treatment in the interruption of clusters in cluster headache patients. Cephalalgia 1987; 7(Suppl 6):332:333.

    Google Scholar 

  201. Cianchetti C, Zuddas A, Marchei F. High dose intravenous methylprednisolone in cluster headache. J Neurol Neurosurg Psychiat 1998; 64:418.

    Article  CAS  PubMed  Google Scholar 

  202. Leone M, Dodick D, Rigamonti A et al. Topiramate in cluster headache prophylaxis: An open trial. Cephalalgia 2003; 23:1001–1002.

    Article  CAS  PubMed  Google Scholar 

  203. Wheeler SD, Carrazana EJ. Topiramate-treated cluster headache. Neurology 1999; 53:234–236.

    CAS  PubMed  Google Scholar 

  204. Leone M, Attanasio A, Grazzi L et al. Transdermal clonidine in the prophylaxis of episodic cluster headache: an open study. Headache 1997; 37:559–560.

    Article  CAS  PubMed  Google Scholar 

  205. Leone M and Rapoport A. Preventive and Surgical Management of Cluster Headache: In: Olesen J, Goadsby PJ, Ramadan N, Tfelt-Hansen P, Welch KMA. The Headaches, 3rd Edition. Lippincott Williams & Wilkins, Philadelphia 2006: 809–814.

    Google Scholar 

  206. May A. and Leone M. Update on cluster headache. Curr Opin Neurol 2003 Jun; 16(3):333–40.

    Article  PubMed  Google Scholar 

  207. Leone M, May A, Franzini A et al. Deep brain stimulation for intractable chronic cluster headache: proposals for patient selection. Cephalalgia 2004; 24 (11):934–937.

    Article  CAS  PubMed  Google Scholar 

  208. Jarrar RG, Black DF, Dodick DW, Davis DH. Outcome of trigeminal nerve section in the treatment of chronic cluster headache. Neurology 2003; 60(8): 1360–1362.

    CAS  PubMed  Google Scholar 

  209. Pieper DR, Dickerson J, Hassenbusch SJ. Percutaneous retrogasserian glycerol rhizolisis for treatemnt of chronic intractable cluster headaches: long-term results. Neurosurgery 2000; 46(2):363–370.

    Article  CAS  PubMed  Google Scholar 

  210. Leone M, Franzini A, Broggi G, May A, Bussone G. Long-term follow up of bilateral hypothalamic stimulation for intractable cluster headache. Brain 2004; 127:2259–2264.

    Article  CAS  PubMed  Google Scholar 

  211. Leone M, Franzini A, Broggi G, Bussone G. Hypothalamic stimulation for intractable cluster headache: longterm experience. Neurology 2006; 67(1):150–152.

    Article  PubMed  Google Scholar 

  212. D’Andrea G, Nordera GP, Piacentino M. Effectiveness of hypothalamic stimulation in two patients affected by intractable chronic cluster headache. Neurology 2006; March Suppl 2 (5): A 140 (abstract).

    Google Scholar 

  213. Schoenen J, Di Clemente L, Vandenheede M et al. Hypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action. Brain 2005; 128:940–947.

    Article  CAS  PubMed  Google Scholar 

  214. Bartsch T, Pinsker MO, Rasche D, Kinfe T, Hertel F, Diener HC, Tronnier V, Mehdorn HM, Volkmann J, Deuschl G, Krauss JK. Hypothalamic deep brain stimulation for cluster headache — experience from a new multicase series. Cephalalgia 2008. In press.

    Google Scholar 

  215. Starr PA, Barbaro NM, Raskin NH, Ostrem JL. Chronic stimulation of the posterior hypothalamic region for cluster headache: technique and 1-year results in four patients. J Neurosurg 2007; 106:999–1005.

    Article  PubMed  Google Scholar 

  216. Cortelli P, Guaraldi P, Leone M et al. Effect of deep brain stimulation of the posterior hypothalamic area on the cardiovascular system in chronic cluster headache patients. Eur J Neurol 2007; 14:1008–1015.

    Article  CAS  PubMed  Google Scholar 

  217. Vetrugno R, Pierangeli G, Leone M et al. Effect on sleep of posterior hypothalamus stimulation in cluster headache. Headache 2007; 47(7):1085–1090.

    Article  PubMed  Google Scholar 

  218. May A, Leone M, Áfra J et al. EFNS guideline on the treatment of cluster headache and other trigemino-autonomic cephalgias. Eur J Neurol 2006; 13:1066–1077.

    Article  CAS  PubMed  Google Scholar 

  219. Leone M, Proietti Cecchini A, Franzini A et al. Lessons from eight years’ experience of hypothalamic stimulation in cluster headache. Head Curr 2008. In press.

    Google Scholar 

  220. Ambrosini A, Vandenheede M, Rossi P et al. Suboccipital injection with a mixture of rapid-and long-acting steroids in cluster headache: a double-blind placebo-controlled study. Pain 2005: 118:92–96.

    Article  CAS  PubMed  Google Scholar 

  221. Afridi SK, Shields KG, Bhola R, Goadsby PJ. Greater occipital nerve injection in primary headache syndromes-prolonged effects from a single injection. Pain 2006; 122(1–2):126–129.

    Article  CAS  PubMed  Google Scholar 

  222. Burns B, Watkins L, Goadsby PJ. Treatment of medically intractable cluster headache by occipital nerve stimulation: long-term follow-up of eight patients. Lancet 2007; 369 (9567):1099–2006.

    Article  PubMed  Google Scholar 

  223. Magis D, Allena M, Bolla M et al. Occipital nerve stimulation for drug-resistant chronic cluster headache: a prospective pilot study. Lancet Neurol 2007; 6:314–321.

    Article  PubMed  Google Scholar 

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Bussone, G., D’Amico, D. (2009). Cefalee. In: Terapia delle malattie neurologiche. Springer, Milano. https://doi.org/10.1007/978-88-470-1120-5_15

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