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Diffusion-Weighted Imaging

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Neurodegeneration in Multiple Sclerosis

Part of the book series: Topics in Neuroscience ((TOPNEURO))

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Abstract

Conventional magnetic resonance imaging (MRI) is widely used for the diagnosis and monitoring of multiple sclerosis (MS), because it is more sensitive than clinical assessment in detecting disease dissemination over space and time [1] and for revealing the occurrence of disease activity and the accumulation of disease burden over time. Nevertheless, the discrepancies between clinical and conventional MRI findings in patients with established MS [2] highlight the fact that conventional MRI is unable to reliably assess the more disabling pathological features of the disease, including axonal and neuronal loss.

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Author information

Authors and Affiliations

  1. Neuroimaging Research Unit Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

    M. Rovaris & M. Filippi

  2. Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

    E. Perego

Authors
  1. M. Rovaris
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  2. E. Perego
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  3. M. Filippi
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Editor information

Editors and Affiliations

  1. Neuroimaging Research Unit Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

    Massimo Filippi  & Marco Rovaris  & 

  2. Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

    Giancarlo Comi

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© 2007 Springer-Verlag Italia

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Rovaris, M., Perego, E., Filippi, M. (2007). Diffusion-Weighted Imaging. In: Filippi, M., Rovaris, M., Comi, G. (eds) Neurodegeneration in Multiple Sclerosis. Topics in Neuroscience. Springer, Milano. https://doi.org/10.1007/978-88-470-0391-0_7

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  • DOI: https://doi.org/10.1007/978-88-470-0391-0_7

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0390-3

  • Online ISBN: 978-88-470-0391-0

  • eBook Packages: MedicineMedicine (R0)

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