Skip to main content
SpringerLink
Log in

References

  • Conference paper
Clinical Aspects and Laboratory Iron Metabolism, Anemias

  • 100 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aisen P (1998) Transferrin, the transferrin receptor, and the uptake of iron by cells. In: Siegel S, Siegel H. (eds). Metal ions in biological systems; Vol 35. Marcel Dekker Inc, New York: 585–631.

    Google Scholar 

  2. Albertini A, Arosio P, Chiancone E, Drysdale J (eds) (1984) Ferritins and isoferritins as biochemical markers. Elsevier,AmsterdamNewYork Oxford

    Google Scholar 

  3. Alford CE, King TTE, Campell PA (1991) Role of transferrin, transferrin receptors and iron in macrophage listericidal activity. J Med 174; 45: 9–466

    Google Scholar 

  4. Andrews NC (1999) Disorders of iron metabolism. N Engl J Med 341: 1986–1995.

    Article  PubMed  CAS  Google Scholar 

  5. Arnett FC, Edworthy SM, Bloch DA, et al. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum, 31: 315–324

    Article  PubMed  CAS  Google Scholar 

  6. Arosio P, Levi S, Gabri E, et al (1984) Heterogeneity of ferritin II: immunological aspects. In: Albertini A, Arosio P, Chiancone E, Drysdale J (eds) Ferritins and isoferritins as biochemical markers. Elsevier, Amsterdam New York Oxford, 33–47

    Google Scholar 

  7. Ascherio A, Rimm EB, Giovanucci E, Willet WC, Stampfer MJ (2001) Blood donation and risk of coronary heart disease. CIRCULATION: 103: 52–57

    Article  PubMed  CAS  Google Scholar 

  8. Ascherio A, Willett WC, Rimm EB, Giovanucci E, Stampfer MJ (1994) Diatory iron intake and risk of coronary disease among men. CIRCULATION: 89: 969–974

    Article  PubMed  CAS  Google Scholar 

  9. Baker EN, Lindley PF (1992) New perspectives on the structure and function of transferrin. J Inorg Biochem 47: 147–160

    Article  PubMed  CAS  Google Scholar 

  10. Baynes RD (1994) Iron Deficiency in Iron Metabolism in Health and Disease (eds. Brock JH, Halliday JW, Pippard MJ, Powell LW) W.B. Saunders Co., 189–198

    Google Scholar 

  11. Baynes RD, Skikne BS, Cook JD (1994) Circulating transferrin receptors and assessment of iron status. J Nutr Biochem 5: 322–330.

    Article  CAS  Google Scholar 

  12. Baynes RD (1996) Assessment of iron status. Clin Biochem 29: 209 — 215

    Google Scholar 

  13. Begemann H, Rastetter J (1993) Klinische Hämatologie, 4. Aufl. Thieme, Stuttgart New York

    Google Scholar 

  14. Beguin Y (1998) Prediction of response to treatment with recombinant human erythropoietin in anemia associated with cancer. Med Oncol 15 (Suppl. 1): 38–46.

    Google Scholar 

  15. Beguin Y (1992) The soluble transferrin receptor: biological aspects and clinical usefulness as quantitative measure of erythropoiesis. Haematologica 77: 1–10

    PubMed  CAS  Google Scholar 

  16. Beguin Y et al (1993) Quantitative asessment of erythropoiesis and functional classification of anemia based on measurement of serum transferrin receptor and Erythropoietin. Blood 81: 1067

    PubMed  CAS  Google Scholar 

  17. Beguin Y (1992) The soluble transferrin receptor: biological aspects and clinical usefulness as quantitative measure of erythropoiesis. Hematologica 77: 1–10

    CAS  Google Scholar 

  18. Besarab A, et al. (1998) The effect of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and Erythropoietin. N Engl J Med 339: 584–590

    Article  PubMed  CAS  Google Scholar 

  19. Beutler E (1997) Genetic irony beyond haemochromatosis: clinical effects of HLA-H mutations. Lancet 349: 296–297

    Article  PubMed  CAS  Google Scholar 

  20. Bobbio-Pallavicini F, et al. (1989) Body iron status in critically ill patients: significance of serum ferritin. Int Care Med 15: 171–178

    Article  CAS  Google Scholar 

  21. Boelaert JR, Weinberg GA, Weinberg ED (1996) Altered iron metabolism in HIV infection: Mechanisms, possible consequences and proposals for management. Inf Dis Agents 5: 36–46

    Google Scholar 

  22. Bothwell TH, et al. (1989) Nutritional iron requirements and food iron absorption. J Intern Med 226: 357–365

    Article  PubMed  CAS  Google Scholar 

  23. Brock JH (1994) Iron in infection, immunity, inflamation and neoplasia in Iron Metabolism in Health and Disease; ed Brock JH, Halliday JW, Pippard MJ, Powell LW London, W.B. Saunders, pp 353–389

    Google Scholar 

  24. Brouwer DAJ, Welten HTME, et al. (1998) Plasma folic acid cutoff value, derived from its relationship with homocyst(e)ine. Clin Chem 44 /7: 1545–1550

    PubMed  CAS  Google Scholar 

  25. Brugnara C (2000) Reticulocyte Cellular Indices: A New Approach in the Diagnosis of Anemias and Monitoring of Erythropoietic Function. Critical Reviews in Clin Lab Sciences; 37 (2): 93–130

    Article  CAS  Google Scholar 

  26. Bunn HF (1991) Anemia associated with chronic disorders. In: Harrison’s principles of internal medicine, 12th ed., McGraw-Hill, New York, 1529–1531

    Google Scholar 

  27. Burns DL, Pomposelli JJ (1999) Toxicity of parenteral iron dextran therapy. Kid Int 55 (SuppI 69): 119–124

    Article  Google Scholar 

  28. Carr H, Rodak BF (1999) Clinical hematology atlas. W. B. Saunders, Philadelphia

    Google Scholar 

  29. Carmel R (1997) Cobalamin, the stomach and aging. Am J Clin Nutr 66: 750–9

    PubMed  CAS  Google Scholar 

  30. Cazzola M, Mercuriali F, Brugnara C, et al. (1997) Use of recombinant human Erythropoietin outside the setting of uraemia. Blood. 89: 4248–4267

    PubMed  CAS  Google Scholar 

  31. Cazzola M, (1996) Defective iron supply for erythropoiesis and adequate endogenous Erythropoietin production in anemia associated with systemic onset invenile chronic arthritis. Blood 87: 4824 — 4830

    Google Scholar 

  32. Cazzola M, Ponchio L, Pedrotti C, et al. (1996) Prediction to response of recombinant human Erythropoietin (rh-EPO) in anaemia of malignancy. Haematologica. 81: 434–441

    PubMed  CAS  Google Scholar 

  33. Cheung W, Minton N, Gunawardena K, et al. (2000) The pharmacokinetics and pharmadynamics of Epoietin Alfa once weekly versus Epoietin Alfa 3 times weekly. Am Soc Haematol; posterpresentation Dec. 4th.

    Google Scholar 

  34. Chiancone E, Stefanini F (1984) Heterogeneity of ferritin I structural and functional aspects. In: Albertini A, Arosio P, Chiancone E, Drysdale J (eds) Ferritins and isoferritins as biochemical markers. Elsevier, Amsterdam New York Oxford, pp 23–31

    Google Scholar 

  35. Cook JD, et al. (1993) Serum transferrin receptor. Ann Rev Med 44: 63

    Article  PubMed  CAS  Google Scholar 

  36. Cook JD, Skikne BS, Baynes RD (1986) Serum transferrin receptor. Blood 687: 726–731

    Google Scholar 

  37. Cook JD, Skikne BS (1989) Iron deficiency: Definition and diagnosis. J Intern Med 226: 349–355.

    Google Scholar 

  38. Cook JD (1982) Clinical evaluation of iron deficiency. Semin Hematol 19: 6–18.

    PubMed  CAS  Google Scholar 

  39. Corti MC, Gaziano M, Hennekeus CH (1997) Iron status and risk of cardiovascular disease. Ann Epidemiol 7: 62–68

    Article  PubMed  CAS  Google Scholar 

  40. Covell AM, Worwood M (1984) Isoferritins in plasma. In: Albertini A, Arosio P, Chiancone E, Drysdale J (eds) Ferritins and isoferritins as biochemical markers. Elsevier, Amsterdam New York Oxford, pp 49–65

    Google Scholar 

  41. Danielson BG, Salmonson T, Derendorf H, Geisser P (1996) Pharmacokinetics of iron(III)-hydroxide sucrose complex after a single intravenous dose in healthy volunteers. Arzneimittelforschung/Drug Res 46 (I) 6

    Google Scholar 

  42. De Jong G, von Dijk IP, van Eijk HG (1990) The biology of transfer-rin. Clin Chim Acta 190: 1–46

    Article  PubMed  Google Scholar 

  43. De Sousa M, Reimao R, Porto G, et al. (1992) Iron and Lymphocytes: Reciprocal regulatory interactions.

    Google Scholar 

  44. Curr Stud Hematol Blood Transf 58: 171–177

    Google Scholar 

  45. Deinhard AS, List A, Lindgren B, Hunt JV, Chang PN (1986) Cognitive deficits in iron-deficient and iron-deficient anaemic children. J Paediatr 108: 681–689

    Article  Google Scholar 

  46. Deutsch E, Geyer G, Wenger R (1992) Folsäure-Resorptionstest. In: Laboratoriumsdiagnostik. Wissenschaftliche Buchreihe, Schering, 91–93

    Google Scholar 

  47. Dietzfelbinger H (1993) Korpuskuläre hämolytische Anämien. In: Begemann H, Rastetter J (Hrsg) Klinische Hämatologie, 4. Aufl. Thieme, Stuttgart New York, 248–252

    Google Scholar 

  48. Dinant JC, de Kock CA, van Wersch JWJ (1995) Diagnostic value of C-reactive protein measurement does not justify replacement of the erythrocyte sedimentation rate in daily general practice. Eur J Clin Invest 25; 353–9

    Article  PubMed  CAS  Google Scholar 

  49. Doss M (1998) Porphyrie. In: Thomas L (Hrsg) Labor and Diagnose. TH-Books, Frankfurt/Main 458–470

    Google Scholar 

  50. Drysdale JW (1977) Ferritin phenotypes: structure and metabolism. In: Jacobs A (ed) Iron metabolism. Ciba Foundation Symposium 51 (excerpta medica). Elsevier, Amsterdam, pp 41–57

    Google Scholar 

  51. Elliot MJ, Maini RN (1994) Repeated therapy with monoclonal antibody to tumor necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 344: 1125–1127

    Article  Google Scholar 

  52. Egrie JC, Dwyer E, Lykos M, et al. (1997) Novel erythropoiesis stimulting protein (NESP) has a longer serum half-life and greater in viro biological activity compared to recombinant human erythropoietin (rHU EPO). Blood 90: 56 A (abstr.)

    Google Scholar 

  53. Egrie JC, Grant JR, Gillias DK, Aoki KH, et al. (1993) The Role of Carbohydrate on the Biological Activity of Erythropoietin. Glycoconjugate Journal; 10: S 7. 7 (abstr.)

    Google Scholar 

  54. Eschbach JW, Haley NR, Adamson JW (1990) The anemia of chronic renal failure: pathophysiology and effects of recombinant Erythropoietin. Contrib Nephrol 78: 24–37

    PubMed  CAS  Google Scholar 

  55. Feelders RA, Kuiper-Kramer EPA, van Eijk HG (1999) Structure, function and clinical significance of transferrin receptors. Clin Chem Lab Med 37: 1–10

    Article  PubMed  CAS  Google Scholar 

  56. Ferguson BJ, Skikne BS, Simpson KM, Baynes RD, Cook JD (1992) Serum transferrin receptor distinguishes the anemia of chronic disease from iron deficiency anemia. J Lab Clin Med 19: 385–390

    Google Scholar 

  57. Finlayson NDC (1990) Hereditary (primary) hemochromatosis. BMJ 301: 350–351

    Article  PubMed  CAS  Google Scholar 

  58. Flowers CH, Skikne BS, Covell AM, Cook JD (1989) The clinical measurement of serum transferrin receptor. J Lab Clin Med 114: 368–377.

    PubMed  CAS  Google Scholar 

  59. Folkman J (1997) Addressing tumor blood vessels. Nat Biotechnol; 15: 110–115.

    Article  Google Scholar 

  60. Franco RS (1987) Ferritin. In: Pesce AJ, Kaplan LA (eds) Methods in clinical chemistry. CV Mosby Company, St. Louis Washington Toronto, pp 1240–1242

    Google Scholar 

  61. Frishman WH (1998) Biologic Markers as Predictors of Cardiovascular Disease. Am J Med; 104: 18s - 27s

    Article  PubMed  CAS  Google Scholar 

  62. Gabrilove JL, et al. (1999) Once weekly dosing of Epoietin Alfa is similar to three times weekly dosing in increasing Hemoglobin and quality of life. Proc ASCO; Vol. 18: 2216 (abstr)

    Google Scholar 

  63. Gargano G, Polignano G, De Lena M, et al. (1999) The utility of a growth factor: rHU-EPO as a treatment for pre-operative autologous blood donation in gynaecological tumor surgery. Int J Oncol; Vol. 4 (1): 157–160.

    Google Scholar 

  64. Garry PJ (1984) Ferritin. In: Hicks JM, Parker KM (eds) Selected analytes in clinical chemistry. American Association for Clincal Chemistry Press, Washington, pp 149–153

    Google Scholar 

  65. Goldberg MA, Dunning SP, Bunn HF (1988) Regulation of the Erythropoietin gene: evidence, that the oxygen sensor is a hemo protein. Science 24w: 1412–1415

    Article  Google Scholar 

  66. Graf H, Lacombe JL, Braun J, et al. (2000) Novel Erythropoiesis stimulating Protein (NESP) for maintains Hemoglobin (Hgb) at a reduced dose frequency compared to recombinant human erythropoietin (EPO) in ESRD patients. Abstr. EDTA 2000

    Google Scholar 

  67. Graf H, Lacombe JL, Braun J, Gomes da Costa AA and the European/Australian NESP 980140/194 Study Group (2000) Am Soc Nephr; 33rd Annual Meeting, Toronto (abstr.)

    Google Scholar 

  68. Graziadei I, Gaggl S, Kaserbacher R, Braunsteiner H, Vogl W (1994) The acute phase protein alpha-1 antitrypsin inhibits growth and proliferation on human early erythroid progenitor cells and of human erythroleucemic cells by interfering with transferrin iron uptake. Blood 83: 260–268

    PubMed  CAS  Google Scholar 

  69. Greendyke RM, Sharma K, Gifford FR (1994) Serum levels of erythropoietin and selected cytokines in patients with anemia of chronic disease. Am Clin Path 101: 338–341

    CAS  Google Scholar 

  70. Grützmacher P, Ehmer B, Messinger D, et al. (1991) Therapy with recombinant human Erythropoietin (rEPO) in hemodialysis patients with transfusion dependent anemia. Report of a European multicenter trial. Nephrologia 11: 58–65

    Google Scholar 

  71. Gunshin H, Mackenzie B, Berger UV, et al. (1997) Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388: 482 488

    Google Scholar 

  72. Hastka J, Lasserre JJ, et al. (1992) Washing erythrocyte to remove interferents in measurements of zinc protoporphyrin by front-face hematofluorometry. Clin Chem 11: 2184–2189

    Google Scholar 

  73. Haupt H, Baudner S (1990) Chemie und klinische Bedeutung der Human Plasma Proteine. Behring Institut Mitteilungen 86: 1–66

    CAS  Google Scholar 

  74. Haverkate F, Thompson SG, et al. (1997) Production of C-reactive protein and risk of coronary events in stable and unstable angina. Lancet 349: 462–466

    Article  PubMed  CAS  Google Scholar 

  75. Heidelberger M, Kendall FE (1935) The precipitin reaction between type III pneumococcus polysaccharide and homologous antibody III. A quantitative study and theory of the reaction mechanism. J Exp Med 61: 563–591

    Google Scholar 

  76. Heil W, Koberstein R, Zawta B (2000) Referenzbereiche für Kinder und Erwachsene, Präanalytik. Roche Diagnostics GmbH, Mannheim

    Google Scholar 

  77. Heinrich HC (1986) Bioverfügbarkeit und therapeutische Wirksamkeit oraler Eisen (3)- und (3) Präparate. Schweiz. Apotheker-Zeitung 22: 1231–1256

    Google Scholar 

  78. Heinrich HC (1980) Diagnostischer Wert des Serumferritins für die Beurteilung der Gesamtkörper-Eisenreserven. In: Kaltwasser JP, Werner E (Hrsg) Serumferritin. Springer, Berlin Heidelberg New York, S 58–95

    Google Scholar 

  79. Henke M, Guttenberger R, Barke A, et al. (1999) Erythropoietin for patients undergoing radiotherapy: a pilot study. Radiother Oncol; Vol 50 (2): 185–190

    Article  PubMed  CAS  Google Scholar 

  80. Henry DH, Abels RI (1994) Recombinant human Erythropoietin in the treatment of cancer and chemotherapy-induced anemia: results of double-blind and open label follow-up studies. Semin Oncol 21 [2 Suppl 31: 21–28

    Google Scholar 

  81. Herrmann W, Schorr H, Purschwitz K, Rassoul F, Richter V (2001) Total Homocysteine, Vitamin B12, and Total Antioxidant Status in Vegetarians. Clin Chem 47: 6 1094–1101

    PubMed  CAS  Google Scholar 

  82. Hermann W, et al. (1997) The Importance of Hyperhomocysteinemia in High Age People. Clin Lab; 43: 1005–1009

    Google Scholar 

  83. Hershko CH, Konijin AM (1981) Serum ferritin in hematologic disorders. In: Albertini A, Arosio P, Chiancone E, Drysdale J (eds) Ferritins and isoferritins as biochemical markers. Elsevier, Amsterdam New York Oxford, pp 143–158

    Google Scholar 

  84. Haman RS, Finch CA (1985) Red Cell Manual. 5th Ed., Davis, Philadelphia

    Google Scholar 

  85. Hörl WH, Cavill I, et al. (1995) How to get the best out of r-HuEPO? Nephrol Dial Transplant 10 (Suppl 2): 92–95

    Article  PubMed  Google Scholar 

  86. Hörl WH, Cavill I, Macdougall IC, Schaefer RM, Sunder-Plassmann G (1996) How to diagnose and correct iron deficiency during rhEPO therapy, a consensus report. Nephrol Dial Transplant 11: 246–250

    Article  PubMed  Google Scholar 

  87. Hörl WH (2001), Persönliche Mitteilung

    Google Scholar 

  88. Huebers HA, Beguin Y, Pootrakne P, Einspahr D, Finch CA (1990) Intact transferrin receptors in human plasma and their relation to erythropoiesis. Blood 75: 102–107

    PubMed  CAS  Google Scholar 

  89. International Committee for Standardisation in Haematology (1988) Recommendations for measurement of serum iron in blood. Int J Hematol 6: 107–111

    Google Scholar 

  90. Jacobs A, Hodgetts J, Hoy TG (1984) Functional aspects of isoferritins. In: Albertini A, Arosio P, Chiancone E, Drysdale J (eds) Ferritins and isoferritins as biochemical markers. Elsevier, Amsterdam New York Oxford, pp 113–127

    Google Scholar 

  91. Jacobs A, Worwood M (1975) Ferritin in serum. N Engl J Med 292: 951–956

    Article  PubMed  CAS  Google Scholar 

  92. Jazwinska EC, et al. (1996) Haemochromatosis and HLAH. Nature Genet 14: 249–251

    Article  PubMed  CAS  Google Scholar 

  93. Johannsen H, Gross AJ, Jelkmann W (1989) Erythropoietin production in malignancy. In: Jelkmann W, Gross AJ (eds) Erythropoietin. Springer, Berlin Heidelberg New York Tokyo, pp 80–91

    Google Scholar 

  94. Johnson AM (1996) Ceruloplasmin. In: Ritchie RF, Navolotskaia O. Serum proteins in clinical medicine. Scarborough: Foundation for Blood Research, 13.01–1–8

    Google Scholar 

  95. Jouanolle AM, et al. (1996) Haemochromatosis and HLA-H. Nature Genet 14: 251–252

    Article  PubMed  CAS  Google Scholar 

  96. Kaltwasser IP, Werner E (Hrsg) (1980) Serumferritin: Methodische und klinische Aspekte. Springer, Berlin Heidelberg New York

    Google Scholar 

  97. Kaltwasser JP, Hörl WH, Cavill J, Thomas L (1999) Anaemia, novel concepts in renal and rheumatoid disease, IFCC-Worldlab-Abstracts, Florence

    Google Scholar 

  98. Kaltwasser JP,Werner E (1980) Serumferritin als Kontrollparameter bei der Therapie des Eisenmangels. In: Kaltwasser JP, Werner E (Hrsg) Serumferritin: Methodische und klinische Aspekte. Springer, Berlin Heidelberg New York, S 137–151

    Chapter  Google Scholar 

  99. Kaltwasser JP, Kessler U, Gottschalk R, Stucki G, Möller B (2001) Effect of rHU-Erythropoietin and i.v. Iron on Anaemia and Disease Activity in Rheumatoid Arthritis. J Rheumatol 28: 2430–2437

    Google Scholar 

  100. Kessler U, Gottschalk R, Stucki G, Kaltwasser JP (1998) Benefit in clinical outcome and disease activity of treatment of anaemia of chronic diseases in rheumatoid arthritis with recombinant human Erythropoietin. J Rheumatol 41: 210

    Google Scholar 

  101. Kiechl S, Willeit J, et al. (1997) Body iron stores and the risk of carotid atherosclerosis: Prospective results from the Bruneck Study. Circulation 96: 3300–3307

    Google Scholar 

  102. Knekt P, Revanen A, et al. (1994) Body iron stores and the risk of cancer. Int J Cancer 56: 379–382

    Article  PubMed  CAS  Google Scholar 

  103. Köhler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256: 495

    Article  PubMed  Google Scholar 

  104. Kolbe-Busch S, Lotz J, Hafner G, Blanckaert J, Claeys G, Togni G, Carlsen J, Röddiger R, Thomas L (2002) Multicenter Evaluation of a Fully Mechanized Soluble Transferrin Receptor Assay on the Hitachi and LOBAS INTEGRA Analyzers and Determination of Reference Ranges. Clin. Chem. Lab. Med. (acceptet 2002 )

    Google Scholar 

  105. Krainer M, Fritz E, Kotzmann H, (1990) Erythropoietin modulates lipid metabolism. Blut 61: Abstr No 81

    Google Scholar 

  106. Kubota K, Tamura J, et al. (1993) Evaluation of increased serum ferritin levels in patients with hyperthyroidism. Clin.Invest 72: 26–29

    Article  Google Scholar 

  107. Leedma PJ, Stein AR, et al. (1996) Thyroid hormone modulates the interaction between iron regulatory proteins and the ferritin mRNA iron responsive element. J Biol. Chem. 271: 12017–12023

    Google Scholar 

  108. Lejeune FJ, Ruegg C, Lienard D (1998) Clinical applications on TNF-alpha in cancer. Curr Opin Immunol 10: 573–580

    Article  PubMed  CAS  Google Scholar 

  109. Leon P, Jimence M, Barona P, Sierrasesumaga L (1998) Recombinant human erythropoietin for the treatment of anemia in children with solid malignant tumors. Med Pediatr Oncol; Vol. 30 (2): 110–116

    Article  PubMed  CAS  Google Scholar 

  110. Liebelt EI (1998) in: Clinical Management of Poisoning and Drug Overdose. WB Saunders 757–766

    Google Scholar 

  111. Lindenbaum J (1988) Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 318: 1720–1728

    Article  PubMed  CAS  Google Scholar 

  112. Linke R, Köppers R (1989) Nicht-isotopische Immunoassays–Ein Überblick. In: Borsdorf R, Fresenius W, Günzler H, et al. (Hrsg) Analytiker-Taschenbuch, Bd 8. Springer, Berlin Heidelberg New York Tokyo, S 127–177

    Chapter  Google Scholar 

  113. Linkesch W (1986) Ferritin bei malignen Erkrankungen. Springer, Wien New York

    Book  Google Scholar 

  114. Linker CH (2000) Blood in Current Diagnosis and Treatment. 39th Ed.: 505–507

    Google Scholar 

  115. Lipschitz DA, Cook JD, Finch CA (1974) A clinical evaluation of serum ferritin as an index of iron stores. N Engl J Med 290: 12131218

    Google Scholar 

  116. Littlewood TJ, Bajetta E, Nortier JW, Vercammen E, Rapoport B (2001) Epoetin Alfa Study Group: Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial. J Clin Oncol; 19 (11): 2865–2874

    PubMed  CAS  Google Scholar 

  117. Liuzzo G, Biasucci LM, Gallimore JR, et al. (1994) The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. N Engl J Med, 331: 417–424

    Article  PubMed  CAS  Google Scholar 

  118. Ludwig H, Chott A, Fritz E (1995) Increase of bone-marrow cellurarity during Erythropoietin treatment in myeloma. Stem Cells (Dayton) 13: [Supp12] 77–87

    CAS  Google Scholar 

  119. Ludwig H, Fritz E, Leitgeb C, Pecherstorfer M, et al. (1994) Prediction of response to Erythropoietin treatment in chronic anemia of cancer. Blood 84: 1056–1063

    PubMed  CAS  Google Scholar 

  120. Ludwig H, Leitgeb C, Pecherstorfer M, (1994) Recombinant human Erythropoietin for the correction of anemia in various cancers. Br J Haematol 87 [Suppl 11: 158 Abstr No 615

    Google Scholar 

  121. MacDougall IC, Gray SJ, Elston O, et al. (1999) Pharmacokinetics of novel erythropoiesis stimulating protein compared with erythropoietin alfa in dialysis patients. I Am Soc Nephrol 10: 2392–2395

    CAS  Google Scholar 

  122. Mac Dougall IC, Roberts DE, Neubert P, et al. (1989) Pharmacokinetics of intravenous, intraperitoneal and subcutanous recombinant erythropoietin in patients on CAPD-A rationale for treatment. Contrib Nephrol 76: 112–121

    Google Scholar 

  123. Maini RN, Breedveld FC, Kalden JR, et al. (1998) Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 41: 1552–1563

    Article  PubMed  CAS  Google Scholar 

  124. Mangold C (1998) The causes and prognostic significance of low hemoglobin levels in tumor patients. Strahlenther Onkol; Vol 174 (Suppl. 4): 17–19

    Google Scholar 

  125. Mantovani G, Ghiani M, Curreli L, et al. (1999) Assessment of the efficacy of two dosages and schedules of human recombinant erythropoietin in prevention and correction of cis-platin induced anemia in cancer patients. Oncol Rep Vol. 6 (2): 421–426

    PubMed  CAS  Google Scholar 

  126. Massey AC (1992) Microcytic anemia. Differential diagnosis and management of iron deficient anemia. Med Clin North Am 76: 549 — 566

    Google Scholar 

  127. Mast AE, Blinder MA, et al. (1998) Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations. Clin Chem 44: 45–51

    PubMed  CAS  Google Scholar 

  128. Means Jr RT, Krantz SB (1992) Progress in understanding the pathogenesis of anemia of chronic disease. Blood 80: 1639–1647

    PubMed  Google Scholar 

  129. Means RT (1995) Pathogenesis of the anemia of chronic disease: A cytokine mediated anemia. Stem. cells (Dayt) 13: 32–37

    Article  Google Scholar 

  130. Means RT, Krantz SB (1992) Progression in understanding the pathogenesis of the anemia of chronic disease. Blood 7: 1639–1647

    Google Scholar 

  131. Menacci A, Cenci E, et al. (1997) Iron overload alters T helper cell responses to Candida albicans in mice. J Infect Dis 175: 1467–1476

    Article  Google Scholar 

  132. Mercuriali F, Gualtieri G, et al. (1994) Use of recombinant human Erythropoietin to assist autologous blood donation by anemic rheumatiod arthritis patients undergoing major orthopedic surgery. Transfusion 34: 501–506

    Article  PubMed  CAS  Google Scholar 

  133. Moldawer LL, Copeland EM (1997) Proinflammatory cytokines, nutritional support, and the cachexia syndrome: interactions and therapeutic options. Cancer 79: 1828–1839

    Article  PubMed  CAS  Google Scholar 

  134. Mutane J, Piug-Parellada P, Mitjavila MT (1995) Iron metabolism and oxidative stress during acute and chronic phases of experimental inflammation. Effect of iron dextran and desferoxamine. J Lab Clin Med 126: 435–443

    Google Scholar 

  135. Nowrousian MR, et al. (1996) Pathophysiology of cancer-related anemia; in Smyth JF, Boogaerts MA, Ehmer BRM (eds): rhErythropoietin in Cancer Supportive Treatment. New York, Dekker, 1996, pp 13–34

    Google Scholar 

  136. Nyman M (1959) Serum haptoglobin methodological and clinical studies. Scand J Clin Lab Invest 11 [Supp139]

    Google Scholar 

  137. O’Neil-Cutting MA, Crosby WH (1986) The effect of antacids on the absorption of simultaneously ingested iron. JAMA 255: 14681470

    Google Scholar 

  138. Park JE, Lentner MC, Zimmermann RN, (1999) Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J Biol Chem 274: 3650536512

    Google Scholar 

  139. Paruta S, Hörl WH (1999) Iron and infection. Kidney International 55 (69), 125–130

    Article  Google Scholar 

  140. Peeters HRM, et al. (1996) Effect of recombinant human Erythropoietin on anaemia and disease activity in patients with rheumatoid arthritis and anaemia of chronic disease: a randomised placebo controlled double blind 52 weeks’ clinical trial. Am Rheum Dis 55: 739–744

    Article  CAS  Google Scholar 

  141. Peeters HRM, Jongen-Lavrencic M, Bakker CH (1999) Recombinant human Erythropoetin improves health-related quality of life in patients with rheumatoid arthritis and anaemia of chronic disease; utility measures correlate strongly with disease activity measures. Rheumatol Int 18: 201–206

    Article  PubMed  CAS  Google Scholar 

  142. Pepys MB (1996) The acute phase response and C-reactive protein. In: Weatherall DJ, Kuller LH, Tracy RP, Shaten J, Meilahn EN. Relation of C-reactive protein and coronary heart disease in the MRFIT nested case control study. Am J Epidemiol, 144: 537–547

    Google Scholar 

  143. Pincus T, et al. (1990) Multicenter study of recombinant human Erythropoietin in correction of anemia in rheumatoid arthritis. Am J Med 89: 161–168

    Article  PubMed  CAS  Google Scholar 

  144. Pinggera W (1999) Personal communication

    Google Scholar 

  145. Ponka P (1997) Tissue-specific regulation of iron metabolism and

    Google Scholar 

  146. heme synthesis: Distinct control mechanisms in erythroid cells. Blood 89: 1–25

    Google Scholar 

  147. Ponka P (1999) Cellular iron metabolism. Kidney International, Vol. 55, Suppl. 69, S2 - S11

    CAS  Google Scholar 

  148. Ponka P, Beaumont C, Richardson R (1998) Function and regulation of transferrin and ferritin. Semin Hematol 35: 35–54.

    PubMed  CAS  Google Scholar 

  149. Punnonen K, et al. (1997) Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 89 /3: 1052–1057

    PubMed  CAS  Google Scholar 

  150. Punnonen K, Irjala K, Rajamäki A (1994) Iron deficiency anemia is associated with high concentrations of transferrin receptor in serum. Clin Chem 40: 774–776

    PubMed  CAS  Google Scholar 

  151. Qvist N, Boesby S, Wolff B, Hansen CP (1999) Recombinant human erythropoietin and hemoglobin concentrations at operation and during the postoperative period. World J Surg; Vol. 23 (1): 30–35

    Article  PubMed  CAS  Google Scholar 

  152. Rauramaa R, Vaisanen S, Mercuri M, et al. (1994) Association of risk factors and body iron status to carotid atherosclerosis in middle aged eastern Finnish men. Eur Heart J 15: 1020–1027

    PubMed  CAS  Google Scholar 

  153. Refsum AB, Schreiner BBI (1984) Regulation of iron balance by absorption and excretion. Scand J Gastroenterol 19: 867–874

    PubMed  CAS  Google Scholar 

  154. Richardson DR, Ponka P (1997) The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochem Biophys Acta 1331: 1–40

    Article  PubMed  CAS  Google Scholar 

  155. Rippmann J, Pfizenmaier K, Mattes R, et al. (2000) Fusion of the tissue factor extracellular domain to a tumour stroma specific single-chain fragment variable antibody results in an antigen-specific coagulation-promoting molecule. Biochem J 349: 1–8

    Article  Google Scholar 

  156. Ritchey AK (1987) Iron deficiency in children. Update of an old problem. Postgrad Med 82: 59–63

    PubMed  CAS  Google Scholar 

  157. Roberts AG, et al. (1997) Increased frequency of the haemochromatosis Cys 282 Tyr mutation in sporadic prophyria cutanea tarda. Lancet 349: 321–323

    Article  PubMed  CAS  Google Scholar 

  158. Robinson SH (1990) Degradation of hemoglobin. In: Williams WJ, Beutler W, Erslev AJ, Lichtman MA (eds) Hematology, 4th edn, McGraw-Hill, New York

    Google Scholar 

  159. Rosenberg IH, Alpers DH (1983) Nutrional deficiencies in gastrointestinal disease. In: Sleisenger MH, Fordtran JS (eds) Gastrointestinal disease, 3`d edn, Saunders, New York, pp 1810–1819

    Google Scholar 

  160. Roth D, Smith RD, Schulman G, et al. (1994) Effects of recombinant human Erythropoietin on renal function in chronic renal failure predialysis patients. Am J Kidney Dis 24: 777–784

    PubMed  CAS  Google Scholar 

  161. Rowland TW, Kelleher JF (1989) . Insights from high school swimmers. Am J Dis Child 143: 197–200

    Google Scholar 

  162. Ruggeri G, Jacobello C, Albertini A, et al. (1984) Studies of human isoferritins in tissues and body fluids. In: Albertini A, Arosio P, Chiancone E, Drysdale J (eds) Ferritins and isoferritins as biochemical markers. Elsevier, Amsterdam New York Oxford, pp 67–78

    Google Scholar 

  163. Sandborn WJ, Hanauer SB (1999) Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results and safety. Inflammatory Bowel Diseases 5 (2), 119–133

    Article  PubMed  CAS  Google Scholar 

  164. Sassa S (1990) Synthesis of heme. In: Williams WJ, Beutler E, Erslev AJ, Lichtman MA (eds) Hematology, 4`h edn, McGraw-Hill, New York, 332–335

    Google Scholar 

  165. Schilling RE, Williams WJ (1995) Vitamin B12-Deficiency: under-diagnosed, overtreated? Hosp Pract 30: 47

    CAS  Google Scholar 

  166. Schultz BM, Freedman ML (1987) Iron deficiency in the elderly. Baillieres Clin Haematol 1: 291–313

    Article  PubMed  CAS  Google Scholar 

  167. Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME (1998) Apoptosis signaling by death receptors. Eur J Biochem 254: 439–459

    Article  PubMed  CAS  Google Scholar 

  168. Schurek HJ (1992) Oxygen shunt diffusion in renal cortex and its physiological link to Erythropoietin production. In: Pagel H, Weiss C, Jelkmann W (eds) Pathophysiology and pharmacology of Erythropoietin. Springer, Berlin Heidelberg New York Tokyo, pp 53–55

    Chapter  Google Scholar 

  169. Scigalla P, Ehmer B, Woll EM, et al. (1990) Zur individuellen Ansprechbarkeit terminal niereninsuffizienter Patienten auf die RhEPO-Therapie. Nieren-Hochdruckerkrankungen 19: 178–183

    Google Scholar 

  170. Scott JM, Weir DG (1980) Drug induced megaloblastic change. Clin Haematol 9: 587–606

    PubMed  CAS  Google Scholar 

  171. Sears D (1992) Anemia of chronic disease. Med Clin North Am 76: 567 — 579

    Google Scholar 

  172. Sempos CT, Looker AC, Gillum RF, McGee DL, Vuong CV, Johnson CL (2000) Serum ferritin and death from all causes and cardiovascular disease: The NHANES II mortality study. AEP 10: 441–448

    Google Scholar 

  173. Shapiro HM (1995) Practical flow cytometry 3`a ed. New York, Wiley-Liss

    Google Scholar 

  174. Shinozuka N, Koyama J, Anzai H, et al. (2000) Autologous blood transfusion in patients with hepatocellular carcinoma undergoing hepatectomy. Am J Surg; Vol. 179 (1): 42–45

    Article  PubMed  CAS  Google Scholar 

  175. Steinberg D, Parthasarathy S, Carew TE, et al. (1989) Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med. 320: 915–924

    Article  PubMed  CAS  Google Scholar 

  176. Sullivan JL (1996) Perspectives on the iron and heart disease debate. J Clin Epidermial 49: 1345–1352

    Article  CAS  Google Scholar 

  177. Sunder-Plassmann G, Hörl WH (1996) Eisen und Erythropoietin. Clin Lab 42: 269–277

    CAS  Google Scholar 

  178. Sunder-Plassmann G, Hörl WH, (1999) Erythropoietin and iron. Clin. Nephrol 47: 141–157

    Google Scholar 

  179. Suominen P, et al. (1997) Evaluation of new immunoenzymometric assay for measuring soluble transferrin receptor to detect iron deficiency in anaemic patients. Clin Chem 43 /9: 1641–1646

    PubMed  CAS  Google Scholar 

  180. Suominen P, Punnonen K, Rajamäki A, Irjala K (1998) Serum transferrin receptor and transferrin receptor-ferritin index identity healthy subjects with subclinical iron deficits. Blood 92: 2934–2939

    PubMed  CAS  Google Scholar 

  181. Sweeney PJ, Nicolae D, Ignacio L, et al. (1988) Effect of subcutaneous recombinant human Erythropoietin in cancer patients receiving radiotherapy: final report of randomized open labeled, phase II trial. Brit J Cancer 77 (11): 1996–2002

    Article  Google Scholar 

  182. Thomas AJ, Bunker VW, et al. (1989) Iron status of hospitalized and housebound elderly people. Q J Med 70: 175–184

    PubMed  CAS  Google Scholar 

  183. Thomas L (Hrsg.) (1998) Labor und Diagnose, 5. Auflage, TH Books Verlagsgesellschaft, Frankfurt

    Google Scholar 

  184. Thomas L, Nowrousian MR, Hörl WH, Möller B, Wick M, et al. (2000) Expert Meeting: Clinical assessment of soluble Transferrin Receptor. Frankfurt

    Google Scholar 

  185. Thomas L, Heimpel H, Hörl WH, Kirschbaum A, Maier RF, Pinggera W, Schäfer RM, Weisbach V, Weiss G, Wick M, et al. (2001) Expert Meeting: Stufendiagnostik bei Eisenstoffwechselstörungen. Frankfurt

    Google Scholar 

  186. Thomas L, Kaltwasser JP, Kuse R, Pinggera W, Scheuermann EH, Wick M (1997) Konsensus Konferenz: Eisensubstitution bei Dialysepatienten unter Erythropoetintherapie. Frankfurt (unpublished )

    Google Scholar 

  187. Thorpe SJ, Walker D, Arosio P, Heath A, Cook JD, Worwood M (19971 International collaborative study to evaluate a recombinant

    Google Scholar 

  188. ferritin preparation as an International Standard. Clin Chem 43: 1582–1587

    Google Scholar 

  189. Thorstensen K, Romslo I (1993) The transferrin receptor: its diagnostic value and its potential as therapeutic target. Scand J Clin Lab Invest 53 [Suppl 2151: 113–120

    Article  Google Scholar 

  190. van Leeuwen MA, van Rijswijk MH, Sluiter WJ, et al. (1997) Individual relationship between progression of radiological damage and the acute phase response in early rheumatoid arthritis. Towards development of a decision support system. J Rheumatol 24: 20–27

    Google Scholar 

  191. Vawenterghem P, Barany P, Mann J, European/Australian NESP 970290 Study Group. Novel Erythropoiesis stimulating Protein (NESP) (1999) Maintains Hemoglobin (Hgb) in ESRD patients when administered once weekly or once every other week. Amer Soc Nephr; 32nd Ann. Meeting A1365

    Google Scholar 

  192. Waheed A, Parkkila S, Saarnio J, Fleening RE, et al. (1999) Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum. Proc. Nat. Acad. Sci. USA 96: 1579–1584

    Google Scholar 

  193. Wajant H, Pfizenmaier K (2001) Vom Tumornekrosefaktor zum TRAIL-AMAIZe: Antitumoral wirksame Zytokine der zweiten Generation. Onkologie 24 (suppl. 1): 6–10

    Article  PubMed  Google Scholar 

  194. Walczak H, Miller RE, Ariail K, et al. (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-indusing ligand in vivo. Nat Med 5: 157–163

    Article  PubMed  CAS  Google Scholar 

  195. Ware CF, Santee S, Glass E (1998) Tumor necrosis factor-related ligands and receptors. In: Thomson AW (ed): Cytokine Handbook. San Diego, Academic Press, pp. 549–593

    Google Scholar 

  196. Weiss G (1999) Iron and anemia of chronic disease. Kidney international 55 (69) 12–17

    Article  Google Scholar 

  197. Weiss G, Fuchs D, Hausen A, Reibnegger G, Werner ER, WernerFelmayer G, Wachter H (1992) Iron modulates interferon gamma effects in the human myelomonocytic cell line THP-1. Exp Hematol 20: 605–610

    PubMed  CAS  Google Scholar 

  198. Weiss G, Houston T, Kastner S, Johrer K, Grunewald K, Brock JH (1997) Regulation of cellular iron metabolism by Erythropoietin: Activation of iron-regulatory protein and upregulation of transferrin receptor expression in erythroid cells. Blood 89: 680

    Google Scholar 

  199. Weiss G, Wachter H, Fuchs D (1995) Linkage of cell-mediated immunity to iron metabolism. Immunol Today 16: 495–500

    Article  PubMed  CAS  Google Scholar 

  200. References

    Google Scholar 

  201. Weiss G, Werner-Felmayer G, Werner ER, Grunewald K, Wachter H, Hentze MW (1994) Iron regulates nitric oxide synthase activity by controlling nuclear transcription. J Exp Med 180: 969

    Article  PubMed  CAS  Google Scholar 

  202. Weiss TL, Kavinsky CJ, Goldwasser E (1982) Characterization of a monoclonal antibody to human Erythropoietin. Proc Natl Acad Sci USA 79: 5465–5469

    Article  PubMed  CAS  Google Scholar 

  203. Wick M, Pinggera W (1994) (personal communication)

    Google Scholar 

  204. Williams WJ, Beutler E, Ersler AJ, Lichtman MA (eds) (1990) Hematology, 4th edn. McGraw-Hill, New York

    Google Scholar 

  205. Worwood M (1980) Serum ferritin. In: Cook JD (ed) Methods in hematology. Churchill Livingstone, New York, pp 55–89

    Google Scholar 

  206. Yanagawa S, Hirade K, Ohnota H (1984) Isolation of human Erythropoietin with monoclonal antibodies. J Biol Chem 259: 27072710

    Google Scholar 

  207. Yap GS, Stevenson MM (1994) Inhibition of in vitro erythropoiesis by soluble mediators of Plasmodium chalandi AS malaria: lack of a major role of interleukin 1, TNF alpha and gamma-Interferon. Infect Immun 62: 357–362

    Google Scholar 

Recommended Reading

  • Andrews NC (1999) Disorders of iron metabolism. N Engl J Med 341: 1986–1995.

    Article  PubMed  CAS  Google Scholar 

  • Begemann H, Rastetter J (1993) Klinische Hämatologie, 4. Aufl. Thieme, Stuttgart New York

    Google Scholar 

  • Beutler E, Lichtman MA, Coller BS, Kipps TH (1995) William’s Hematology. 5’h ed. McGraw-Hill, New York

    Google Scholar 

  • Brostoff J (1997) Taschenatlas der Immunologie: Grundlagen, Labor, Klinik. Thieme, Stuttgart, New York

    Google Scholar 

  • Burmester G (1998) Taschenatlas der Immunologie: Grundlagen, Labor, Klinik. Thieme, Stuttgart, New York

    Google Scholar 

  • Greiling H, Gressner AM (eds) (1995) Lehrbuch der klinischen Chemie und Pathobiochemie, 3. Aufl. Schattauer, Stuttgart New York

    Google Scholar 

  • Heil W, Koberstein R, Zawta B (2002) Referenzbereiche für Kinder und Erwachsene, Pre-Analytical Considerations. Roche Diagnostics GmbH, Mannheim

    Google Scholar 

  • Kaltwasser IP, Werner E (Hrsg) (1980) Serumferritin: Methodische und klinische Aspekte. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Klein J, Horejsi N (1999) Immunology, 2°a edn. Blackwell Science, Oxford Malden Carlton

    Google Scholar 

  • Porstmann B (1993) Retikulozyten — Reifung, Analytik, Klinische Bedeutung. Wachholz, Nürnberg

    Google Scholar 

  • Sunder-Plassmann G, Hoerl WH, Guest Editors (1999) Kidney International, Vol 55, Suppl 69

    Google Scholar 

  • Themel H, Schick HD (1998) Praktische Differentialdiagnostik in Hämatologie und Onkologie. Thieme, Stuttgart, New York

    Google Scholar 

  • Thomas L (Hrsg) (1998) Labor und Diagnose, 5. Aufl. TH Books Verlagsgesellschaft, Frankfurt

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Clinical Chemistry, Klinikum Grosshadern, University of Munich, Germany

    Dr. Manfred Wick

  2. Roche Diagnostics GmbH, Mannheim, Germany

    Dr. Paul Lehmann

  3. Medical Department, General Hospital, Amstetten, Austria

    Prim. Univ.-Prof. Dr. Wulf Pinggera

Authors
  1. Dr. Manfred Wick
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dr. Paul Lehmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Prim. Univ.-Prof. Dr. Wulf Pinggera
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Wien

About this paper

Cite this paper

Wick, M., Lehmann, P., Pinggera, W. (2003). References. In: Clinical Aspects and Laboratory Iron Metabolism, Anemias. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3719-2_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-3719-2_12

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-00695-5

  • Online ISBN: 978-3-7091-3719-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation