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Myometrial Electrophysiology

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Basic Mechanisms Controlling Term and Preterm Birth

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 7))

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Abstract

Ion channels involve in the generation of electrical events can be separated in at least three different groups. Voltage-gated ion channels mediate rapid, voltage-dependent changes in membrane conductance during action potentials. Calcium, sodium and potassium channels belong to this group. Ligand-gated ion channels are opened in response to activation of an associated receptor. Typical channels of this type include the nonspecific channels that are opened by activation of muscarinic receptors (Benham et al. 1985) or ATP-receptors (Benham et al. 1987; Friel 1988; Honoré et al. 1989a). Activation of ligand-gated ion channels mediates local increases in membrane conductance, producing depolarization and hyperpolarization of the membrane. Calcium-gated channels are only opened by an increase in cytoplasmic calcium and modulate the membrane potential. Potassium and chloride channels of this type have been identified in smooth muscle (Coleman and Parkington 1987; Pacaud et al. 1989).

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Authors
  1. Jean Mironneau
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K. Chwalisz R. E. Garfield

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© 1994 Springer-Verlag Berlin Heidelberg

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Mironneau, J. (1994). Myometrial Electrophysiology. In: Chwalisz, K., Garfield, R.E. (eds) Basic Mechanisms Controlling Term and Preterm Birth. Ernst Schering Research Foundation Workshop, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-21660-6_3

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  • DOI: https://doi.org/10.1007/978-3-662-21660-6_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-21662-0

  • Online ISBN: 978-3-662-21660-6

  • eBook Packages: Springer Book Archive

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