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Pharmacological Basis for the Therapy of Osteoarthritis

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Osteoarthritis

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Abstract

For a targeted pharmacologically oriented basic therapy for osteoarthritis, it is important that the drugs should act against the underlying process of cartilage destruction. A deep insight and exact knowledge of the pathogenetic reactions that occur during the course of degenerative joint disease are necessary for the development of such agents. Fortunately, from the field of experimental osteoarthritis research, a large number of new and interesting findings have come to light over the last 5–10 years concerning the pathogenesis of osteoarthritic joint dysfunction. In order to illustrate the present possible starting points for a pharmacological intervention, some aspects of the pathogenesis of osteoarthritis is first briefly described as it is currently understood.

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Authors
  1. J. Steinmeyer
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Editors and Affiliations

  1. Department of Orthopaedics, St. Josef-Hospital, Ruhr-University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany

    Joachim Grifka MD (Professor of Orthopaedic Surgery) (Professor of Orthopaedic Surgery)

  2. Edith Cavell Wing 1-032, University of Toronto and the Toronto Hospital, 399 Bathurst Street, M5T 2S8, Toronto, Canada

    Darrell J. Ogilvie-Harris MD (Professor of Orthopaedic Surgery) (Professor of Orthopaedic Surgery)

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© 2000 Springer-Verlag Berlin · Heidelberg

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Steinmeyer, J. (2000). Pharmacological Basis for the Therapy of Osteoarthritis. In: Grifka, J., Ogilvie-Harris, D.J. (eds) Osteoarthritis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87752-0_5

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  • DOI: https://doi.org/10.1007/978-3-642-87752-0_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-87754-4

  • Online ISBN: 978-3-642-87752-0

  • eBook Packages: Springer Book Archive

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