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Bisphosphonates: Mechanisms of Action and Clinical Use

  • Chapter
Physiology and Pharmacology of Bone

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 107))

Abstract

The bisphosphonates are a new class of drugs which have been developed in the past 2 decades for use in various diseases of bone, tooth, and calcium metabolism. This chapter will cover the chemistry, the mechanisms of action, and the clinical applications of these compounds. Since a review was published on the same topic in this handbook in 1988 (Fleisch 1988), some parts which were extensively discussed there will be kept short. Emphasis will be on newer developments and on clinical aspects. For complete information the reader should consult both articles.

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  1. H. Fleisch
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© 1993 Springer-Verlag Berlin Heidelberg

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Fleisch, H. (1993). Bisphosphonates: Mechanisms of Action and Clinical Use. In: Physiology and Pharmacology of Bone. Handbook of Experimental Pharmacology, vol 107. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77991-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-77991-6_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77993-0

  • Online ISBN: 978-3-642-77991-6

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