Abstract
The interruption of the continuity of axons, such as may occur with spinal or cranial nerve injury or as a result of compression or inflammation, leads to characteristic retrograde changes in the cell bodies of the affected neurons. These changes are part of a regenerative process which involves not only the lesioned neurons but also their microenvironment. Although regeneration may result in the anatomical restitution of a lesioned nerve, i.e., by neurite outgrowth and reinnervation of the musculature, functional recovery does not always take place.
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© 1990 Springer-Verlag Berlin Heidelberg
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Kreutzberg, G.W., Graeber, M.B. (1990). Cellular Biology of the Experimental Peripheral Nerve Lesion. In: Samii, M. (eds) Peripheral Nerve Lesions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75611-5_1
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DOI: https://doi.org/10.1007/978-3-642-75611-5_1
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