Abstract
Brain edema is frequently a major determinant of the clinical course and outcome in acute insults of the brain. Based on pathophysiological investigations, Klatzo [9] introduced more than 20 years ago the now classical distinction of brain edema into its vasogenic and cytotoxic manifestations. Although the vasogenic edema type seems to predominate, both types of brain edema occur simultaneously under clinical conditions. The availability of computer tomography and, more recently, of magnetic resonance imaging (MRI) for the first time provides a direct diagnosis of brain edema in patients [11]. Such diagnosis was formerly based on indirect measures, such as increased intracranial pressure. However, even with these new imaging techniques a differential diagnosis between vasogenic and cytotoxic edema is not yet possible.
Supported by Deutsche Forschungsgemeinschaft: BA 452 and Un 56/1–1.
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Unterberg, A., Baethmann, A., Wahl, M., Schürer, L., Marmarou, A. (1987). New Aspects in the Formation of Vasogenic Brain Edema. In: Baethmann, A., Messmer, K. (eds) Surgical Research: Recent Concepts and Results. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73097-9_1
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