Abstract
Hepatocellular carcinoma (HCC) is still seen as a neoplasm with a very grim prognosis. This concept was established decades ago, when the diagnosis was almost always achieved at an advanced stage or even after death. However, the availability of ultrasound (US) and its wide use in the conventional clinical setting for the evaluation of patients with suspicion of liver disease has prompted a radical change in the timing of diagnosis. Patients with HCC may be now diagnosed at an early asymptomatic stage (Okuda 1986) when potentially effective therapies can be indicated and this has raised a marked interest in defining the criteria and staging systems that should be used to properly manage HCC patients.
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Bruix, J., Bru, C. (1999). Rationale for Non-surgical Interventional Treatment of Hepatocellular Carcinoma. In: Bartolozzi, C., Lencioni, R. (eds) Liver Malignancies. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58641-5_16
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DOI: https://doi.org/10.1007/978-3-642-58641-5_16
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