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Surgical Management of Hepatocellular Carcinoma

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Hepato-Pancreato-Biliary Malignancies

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Abstract

It is crucial to tailor the surgical management of hepatocellular carcinoma (HCC) to clinical pictures of end-stage liver disease to avoid dramatic neoplastic progression and negative outcomes.

The timing of HCC recognition, its extent, the patient’s condition, and the availability of a referral hepatobiliary center influence the complexity of the treatment and clinical outcomes.

It is known, for example, that the best results in terms of prognostic and efficacious treatment are obtained when the HCC lesion is detected early.

When HCCs are unfit for liver resection and/or associated with end-stage liver disease (ESLD), a complex clinical condition may require liver transplantation (LT) or possibly even interventional radiological procedures as a neoadjuvant bridging option.

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Authors and Affiliations

  1. Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, IRCCS ISMETT (Istituto di Ricovero e Cura a Carattere Scientifico – Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), UPMC (University of Pittsburgh Medical Center) Italy, Palermo, Italy

    Duilio Pagano, Sergio Calamia & Salvatore Gruttadauria

  2. Department of Diagnostic and Therapeutic Services, IRCCS ISMETT (Istituto di Ricovero e Cura a Carattere Scientifico – Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), UPMC (University of Pittsburgh Medical Center) Italy, Palermo, Italy

    Giuseppe Mamone

  3. Department of Surgery and Surgical and Medical Specialties, University of Catania, Catania, Italy

    Salvatore Gruttadauria

Authors
  1. Duilio Pagano
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  2. Giuseppe Mamone
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  3. Sergio Calamia
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  4. Salvatore Gruttadauria
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Corresponding author

Correspondence to Salvatore Gruttadauria .

Editor information

Editors and Affiliations

  1. Medical Director, Capital Health Medical Center Hopewell, Pennington, NJ, USA

    Cataldo Doria

  2. Capital Health Center for Digestive Health, Pennington, NJ, USA

    Jason N. Rogart

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Pagano, D., Mamone, G., Calamia, S., Gruttadauria, S. (2021). Surgical Management of Hepatocellular Carcinoma. In: Doria, C., Rogart, J.N. (eds) Hepato-Pancreato-Biliary Malignancies. Springer, Cham. https://doi.org/10.1007/978-3-030-37482-2_7-1

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  • DOI: https://doi.org/10.1007/978-3-030-37482-2_7-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-37482-2

  • Online ISBN: 978-3-030-37482-2

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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