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Immunogenetics of Aging

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Immunology of Aging

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Abstract

The importance of environment, genetics, and stochasticity factors are changed with longevity. It is well documented that the quality and the size of the humoral immune response decline with age. The individuals, genetically enriched for longevity, possess different immune signatures comparing to the general population. Human leukocyte antigen and cytokine gene polymorphisms are two examples with some associations with ageing. The genetic factors coding the immune system in association with ageing have been described in this chapter.

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  1. Molecular Immunology Research Center and Departement of Immunology, Tehran University of Medical Sciences, Tehran, Iran

    Ali Akbar Amirzargar PhD

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  1. Ali Akbar Amirzargar PhD
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Correspondence to Ali Akbar Amirzargar PhD .

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  1. Department of Immunology, Tehran University of Medical Sciences School of Medicine, Tehran, Iran

    Ahmad Massoud

  2. Children's Medical Center Hospital, Tehran University of Medical Sciences Research Center for Immunodeficiencies, Tehran, Iran

    Nima Rezaei

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Amirzargar, A.A. (2014). Immunogenetics of Aging. In: Massoud, A., Rezaei, N. (eds) Immunology of Aging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-39495-9_16

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